SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vwv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HZQ_A_STRA300_1 (APOLIPOPROTEIN D)	3vwv	PEROXIREDOXIN-4 (Mus musculus)	4 / 7	THR A 146 ALA A 88 TYR A 191 LEU A 106	None	1.09A	2hzqA-3vwvA: undetectable	2hzqA-3vwvA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_B_KLNB1499_1 (CYTOCHROME P450 3A4)	3vwv	PEROXIREDOXIN-4 (Mus musculus)	4 / 7	PHE A 117 THR A 218 ILE A 175 GLY A 225	None	0.77A	2v0mB-3vwvA: undetectable	2v0mB-3vwvA: 18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_D_SAMD301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	3vwv	PEROXIREDOXIN-4 (Mus musculus)	5 / 12	GLY A 204 SER A 188 ILE A 217 ASP A 221 LEU A 219	None	1.31A	3iv6D-3vwvA: undetectable	3iv6D-3vwvA: 24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7U_D_YTZD802_1 (SEPIAPTERIN REDUCTASE)	3vwv	PEROXIREDOXIN-4 (Mus musculus)	4 / 8	LEU A 180 PHE A 116 TYR A 119 PRO A 178	None	1.02A	4j7uD-3vwvA: undetectable	4j7uD-3vwvA: 23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6IEY_A_CLMA401_0 (ESTERASE)	3vwv	PEROXIREDOXIN-4 (Mus musculus)	5 / 11	ILE A 175 HIS A 159 ASP A 122 SER A 152 ALA A 150	None	1.33A	6ieyA-3vwvA: undetectable 6ieyB-3vwvA: undetectable	6ieyA-3vwvA: 21.07 6ieyB-3vwvA: 21.07

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HZQ_A_STRA300_1","APOLIPOPROTEIN D","3vwv","PEROXIREDOXIN-4","Mus musculus",4,"THR A 146;ALA A  88;TYR A 191;LEU A 106","None","1.09A","2hzqA-3vwvA:undetectable","2hzqA-3vwvA:21.10"],["2V0M_B_KLNB1499_1","CYTOCHROME P450 3A4","3vwv","PEROXIREDOXIN-4","Mus musculus",4,"PHE A 117;THR A 218;ILE A 175;GLY A 225","None","0.77A","2v0mB-3vwvA:undetectable","2v0mB-3vwvA:18.68"],["3IV6_D_SAMD301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","3vwv","PEROXIREDOXIN-4","Mus musculus",5,"GLY A 204;SER A 188;ILE A 217;ASP A 221;LEU A 219","None","1.31A","3iv6D-3vwvA:undetectable","3iv6D-3vwvA:24.73"],["4J7U_D_YTZD802_1","SEPIAPTERIN REDUCTASE","3vwv","PEROXIREDOXIN-4","Mus musculus",4,"LEU A 180;PHE A 116;TYR A 119;PRO A 178","None","1.02A","4j7uD-3vwvA:undetectable","4j7uD-3vwvA:23.19"],["6IEY_A_CLMA401_0","ESTERASE","3vwv","PEROXIREDOXIN-4","Mus musculus",5,"ILE A 175;HIS A 159;ASP A 122;SER A 152;ALA A 150","None","1.33A","6ieyA-3vwvA:undetectable;6ieyB-3vwvA:undetectable","6ieyA-3vwvA:21.07;6ieyB-3vwvA:21.07"]]