SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vwx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W68_B_VIVB301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	3vwx	GLUTATHIONE S-TRANSFERASE 6B (Musca domestica)	5 / 12	ILE A 115 VAL A 213 VAL A 15 LEU A 36 VAL A 55	None None None GSH A 500 (-4.4A) GSH A 500 (-3.9A)	1.13A	3w68B-3vwxA: undetectable	3w68B-3vwxA: 22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JWA_H_ACTH612_0 (NADH DEHYDROGENASE, PUTATIVE)	3vwx	GLUTATHIONE S-TRANSFERASE 6B (Musca domestica)	3 / 3	ARG A 122 PRO A 118 ASN A 114	None	1.07A	5jwaA-3vwxA: undetectable 5jwaH-3vwxA: undetectable	5jwaA-3vwxA: 19.54 5jwaH-3vwxA: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_A_NOVA403_2 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	3vwx	GLUTATHIONE S-TRANSFERASE 6B (Musca domestica)	4 / 6	ARG A 113 LEU A 112 ALA A 173 GLN A 109	GSH A 500 (-2.9A) None None None	0.98A	6b89B-3vwxA: undetectable	6b89B-3vwxA: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EFN_A_SAMA501_0 (SPORULATION KILLING FACTOR MATURATION PROTEIN SKFB)	3vwx	GLUTATHIONE S-TRANSFERASE 6B (Musca domestica)	5 / 11	THR A 169 ALA A 17 THR A 158 LEU A 157 ALA A 153	None	1.44A	6efnA-3vwxA: undetectable	6efnA-3vwxA: 20.73

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3W68_B_VIVB301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","3vwx","GLUTATHIONE S-TRANSFERASE 6B","Musca domestica",5,"ILE A 115;VAL A 213;VAL A  15;LEU A  36;VAL A  55","None;None;None;GSH A 500 (-4.4A);GSH A 500 (-3.9A)","1.13A","3w68B-3vwxA:undetectable","3w68B-3vwxA:22.26"],["5JWA_H_ACTH612_0","NADH DEHYDROGENASE, PUTATIVE","3vwx","GLUTATHIONE S-TRANSFERASE 6B","Musca domestica",3,"ARG A 122;PRO A 118;ASN A 114","None","1.07A","5jwaA-3vwxA:undetectable;5jwaH-3vwxA:undetectable","5jwaA-3vwxA:19.54;5jwaH-3vwxA:19.54"],["6B89_A_NOVA403_2","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB;LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","3vwx","GLUTATHIONE S-TRANSFERASE 6B","Musca domestica",4,"ARG A 113;LEU A 112;ALA A 173;GLN A 109","GSH A 500 (-2.9A);None;None;None","0.98A","6b89B-3vwxA:undetectable","6b89B-3vwxA:20.31"],["6EFN_A_SAMA501_0","SPORULATION KILLING FACTOR MATURATION PROTEIN SKFB","3vwx","GLUTATHIONE S-TRANSFERASE 6B","Musca domestica",5,"THR A 169;ALA A  17;THR A 158;LEU A 157;ALA A 153","None","1.44A","6efnA-3vwxA:undetectable","6efnA-3vwxA:20.73"]]