SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vxm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 3vxm C1-28 TCR BETA CHAIN
(Homo
sapiens) 		5 / 12 LEU E  78
SER E  65
PHE E  64
LEU E  21
PHE E  47
 None
 1.26A 3ko0A-3vxmE:
undetectable
3ko0B-3vxmE:
undetectable
3ko0C-3vxmE:
undetectable
3ko0D-3vxmE:
undetectable		 3ko0A-3vxmE:
21.30
3ko0B-3vxmE:
21.30
3ko0C-3vxmE:
21.30
3ko0D-3vxmE:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NHX_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 3vxm C1-28 TCR BETA CHAIN
(Homo
sapiens) 		5 / 12 LEU E  11
ASP E 220
PHE E 213
VAL E 119
ASN E  17
 None
 1.40A 3nhxA-3vxmE:
undetectable		 3nhxA-3vxmE:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3vxm C1-28 TCR BETA CHAIN
(Homo
sapiens) 		4 / 5 HIS E  29
SER E  94
THR E  96
GLU E 101
 None
 1.31A 3tm4A-3vxmE:
undetectable		 3tm4A-3vxmE:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3vxm C1-28 TCR BETA CHAIN
(Homo
sapiens) 		4 / 5 HIS E  29
SER E  94
THR E  96
GLU E 101
 None
 1.33A 3tm4B-3vxmE:
undetectable		 3tm4B-3vxmE:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8A_F_ACTF803_0
(UNCHARACTERIZED
PROTEIN)		 3vxm C1-28 TCR BETA CHAIN
(Homo
sapiens) 		4 / 4 MET E  46
TYR E  89
ARG E  63
LEU E  76
 None
 1.33A 6d8aF-3vxmE:
0.0		 6d8aF-3vxmE:
16.31