SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vyg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vyg THIOCYANATE
HYDROLASE SUBUNIT
ALPHA
(Thiobacillus
thioparus) 		3 / 3 GLU A 115
THR A 116
LEU A 101
 None
 0.72A 1v8bC-3vygA:
undetectable		 1v8bC-3vygA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 3vyg THIOCYANATE
HYDROLASE SUBUNIT
ALPHA
(Thiobacillus
thioparus) 		4 / 7 ILE A  94
LEU A 114
TYR A  59
ILE A 118
 None
 0.78A 4y03A-3vygA:
undetectable		 4y03A-3vygA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 3vyg THIOCYANATE
HYDROLASE SUBUNIT
ALPHA
THIOCYANATE
HYDROLASE SUBUNIT
BETA
(Thiobacillus
thioparus;
Thiobacillus
thioparus) 		4 / 8 THR B  86
HIS A  14
PHE A  28
PRO A  75
 None
 1.20A 5v4vA-3vygB:
undetectable		 5v4vA-3vygB:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 3vyg THIOCYANATE
HYDROLASE SUBUNIT
ALPHA
THIOCYANATE
HYDROLASE SUBUNIT
BETA
(Thiobacillus
thioparus;
Thiobacillus
thioparus) 		4 / 8 THR B  86
HIS A  14
PHE A  28
PRO A  75
 None
 1.19A 5v4vB-3vygB:
undetectable		 5v4vB-3vygB:
16.75