SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vyl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A  99
LEU A  50
VAL A  45
SER A  38
 None
 0.99A 1dfoA-3vylA:
undetectable		 1dfoA-3vylA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A 100
LEU A  50
VAL A  45
SER A  38
 None
 1.07A 1dfoA-3vylA:
undetectable		 1dfoA-3vylA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A  99
LEU A  50
VAL A  45
SER A  38
 None
 0.99A 1dfoB-3vylA:
undetectable		 1dfoB-3vylA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A 100
LEU A  50
VAL A  45
SER A  38
 None
 1.07A 1dfoB-3vylA:
undetectable		 1dfoB-3vylA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A  99
LEU A  50
VAL A  45
SER A  38
 None
 0.99A 1dfoC-3vylA:
undetectable		 1dfoC-3vylA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A 100
LEU A  50
VAL A  45
SER A  38
 None
 1.07A 1dfoC-3vylA:
undetectable		 1dfoC-3vylA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A  99
LEU A  50
VAL A  45
SER A  38
 None
 0.99A 1dfoD-3vylA:
undetectable		 1dfoD-3vylA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A 100
LEU A  50
VAL A  45
SER A  38
 None
 1.07A 1dfoD-3vylA:
undetectable		 1dfoD-3vylA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		4 / 6 TYR A 234
ASP A 237
VAL A 205
GLY A 203
 None
 1.05A 1ekjC-3vylA:
undetectable
1ekjD-3vylA:
undetectable		 1ekjC-3vylA:
23.61
1ekjD-3vylA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3007_0
(BETA-CARBONIC
ANHYDRASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		4 / 6 ASP A 237
VAL A 205
GLY A 203
TYR A 234
 None
 1.09A 1ekjC-3vylA:
undetectable
1ekjD-3vylA:
undetectable		 1ekjC-3vylA:
23.61
1ekjD-3vylA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A  99
LEU A  50
VAL A  45
SER A  38
 None
 0.97A 1eqbA-3vylA:
undetectable		 1eqbA-3vylA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A 100
LEU A  50
VAL A  45
SER A  38
 None
 1.04A 1eqbA-3vylA:
undetectable		 1eqbA-3vylA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A  99
LEU A  50
VAL A  45
SER A  38
 None
 0.97A 1eqbB-3vylA:
undetectable		 1eqbB-3vylA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A 100
LEU A  50
VAL A  45
SER A  38
 None
 1.04A 1eqbB-3vylA:
undetectable		 1eqbB-3vylA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A  99
LEU A  50
VAL A  45
SER A  38
 None
 0.97A 1eqbC-3vylA:
undetectable		 1eqbC-3vylA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A 100
LEU A  50
VAL A  45
SER A  38
 None
 1.03A 1eqbC-3vylA:
undetectable		 1eqbC-3vylA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A  99
LEU A  50
VAL A  45
SER A  38
 None
 0.97A 1eqbD-3vylA:
undetectable		 1eqbD-3vylA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A  98
GLY A 100
LEU A  50
VAL A  45
SER A  38
 None
 1.04A 1eqbD-3vylA:
undetectable		 1eqbD-3vylA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 11 ILE A  65
GLY A 105
GLU A 147
LEU A 252
GLU A  36
 None
None
MN  A1001 (-2.5A)
None
None
 1.41A 1i7qA-3vylA:
undetectable		 1i7qA-3vylA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 ILE A  35
ILE A  47
LEU A  98
VAL A  61
ILE A  63
 None
 0.88A 1oipA-3vylA:
undetectable		 1oipA-3vylA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_A_FCNA1199_1
(EPOXIDASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 9 LEU A  34
HIS A 206
GLU A  36
HIS A 178
ALA A  62
 None
MN  A1001 (-3.2A)
None
None
None
 1.18A 2bnnA-3vylA:
undetectable
2bnnB-3vylA:
undetectable		 2bnnA-3vylA:
23.51
2bnnB-3vylA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 8 LEU A  34
HIS A 206
GLU A  36
HIS A 178
ALA A  62
 None
MN  A1001 (-3.2A)
None
None
None
 1.25A 2bnnA-3vylA:
undetectable
2bnnB-3vylA:
undetectable		 2bnnA-3vylA:
23.51
2bnnB-3vylA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 11 LEU A  59
LEU A  57
ILE A   6
ASN A 266
LEU A  98
 None
 1.37A 2ft9A-3vylA:
undetectable		 2ft9A-3vylA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 ILE A 202
ALA A 134
HIS A 178
LEU A 146
LEU A 107
 None
 0.98A 2yqzA-3vylA:
undetectable		 2yqzA-3vylA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		4 / 8 THR A  23
LEU A  50
ASP A  44
GLU A  36
 None
 0.97A 2zw9A-3vylA:
undetectable		 2zw9A-3vylA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 LEU A 146
LEU A  88
ILE A 106
ALA A 109
SER A 126
 None
 0.99A 3n8zB-3vylA:
undetectable		 3n8zB-3vylA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1224_0
(THAUMATIN-LIKE
PROTEIN)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		4 / 5 SER A  64
GLU A 241
TYR A 204
ASP A 180
 None
MN  A1001 (-2.3A)
None
MN  A1001 (-3.1A)
 1.49A 3zs3A-3vylA:
undetectable		 3zs3A-3vylA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 8 ILE A 220
ASP A 221
ILE A 225
PHE A 226
VAL A 205
 None
 1.46A 4acaC-3vylA:
2.0		 4acaC-3vylA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 8 ILE A 220
ASP A 221
ILE A 225
PHE A 226
VAL A 205
 None
 1.43A 4acbC-3vylA:
2.2		 4acbC-3vylA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		3 / 3 HIS A   7
TRP A 263
SER A  64
 None
 1.22A 4lrhD-3vylA:
undetectable		 4lrhD-3vylA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		3 / 3 GLU A 147
THR A 256
HIS A 111
 MN  A1001 (-2.5A)
None
None
 0.86A 4q15A-3vylA:
undetectable		 4q15A-3vylA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		3 / 3 GLU A 147
THR A 256
HIS A 111
 MN  A1001 (-2.5A)
None
None
 0.83A 4q15B-3vylA:
undetectable		 4q15B-3vylA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 HIS A 178
GLU A 147
HIS A 206
GLU A  36
LEU A  24
 None
MN  A1001 (-2.5A)
MN  A1001 (-3.2A)
None
None
 1.43A 4r7lA-3vylA:
undetectable		 4r7lA-3vylA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 9 LEU A  59
GLY A  60
ILE A   6
SER A   8
THR A  27
 None
 1.45A 4x3mA-3vylA:
3.0		 4x3mA-3vylA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		3 / 3 GLU A 147
THR A 256
HIS A 111
 MN  A1001 (-2.5A)
None
None
 0.82A 4ydqB-3vylA:
undetectable		 4ydqB-3vylA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		5 / 12 ILE A  35
ILE A  47
LEU A  98
VAL A  61
ILE A  63
 None
 0.86A 5mueA-3vylA:
1.6		 5mueA-3vylA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		4 / 7 GLY A 105
HIS A 178
ASP A 180
HIS A   7
 None
None
MN  A1001 (-3.1A)
None
 0.88A 5nnwD-3vylA:
undetectable		 5nnwD-3vylA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		4 / 7 GLY A 105
HIS A 178
ASP A 180
HIS A   7
 None
None
MN  A1001 (-3.1A)
None
 0.89A 5no9D-3vylA:
undetectable		 5no9D-3vylA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 3vyl L-RIBULOSE
3-EPIMERASE
(Mesorhizobium
loti) 		4 / 7 GLY A   5
HIS A 272
GLU A 209
GLY A 208
 None
 0.81A 6n7fA-3vylA:
undetectable		 6n7fA-3vylA:
15.44