SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vz0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 SER A 385
GLY A 391
ALA A 382
THR A 410
 None
 0.72A 1c9sI-3vz0A:
undetectable
1c9sJ-3vz0A:
undetectable		 1c9sI-3vz0A:
10.20
1c9sJ-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 7 GLY A 391
ALA A 382
THR A 410
SER A 385
 None
 0.69A 1c9sT-3vz0A:
undetectable
1c9sU-3vz0A:
undetectable		 1c9sT-3vz0A:
10.20
1c9sU-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 GLY A 391
ALA A 382
THR A 410
SER A 385
 None
 0.68A 1c9sU-3vz0A:
undetectable
1c9sV-3vz0A:
undetectable		 1c9sU-3vz0A:
10.20
1c9sV-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		3 / 3 TRP A  37
VAL A 153
TRP A  41
 None
 1.46A 1gmkC-3vz0A:
undetectable
1gmkD-3vz0A:
undetectable		 1gmkC-3vz0A:
7.86
1gmkD-3vz0A:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 7 GLY A 391
ALA A 382
THR A 410
SER A 385
 None
 0.68A 1gtfL-3vz0A:
undetectable
1gtfM-3vz0A:
undetectable		 1gtfL-3vz0A:
10.20
1gtfM-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 GLY A 391
ALA A 382
THR A 410
SER A 385
 None
 0.69A 1gtfN-3vz0A:
undetectable
1gtfO-3vz0A:
undetectable		 1gtfN-3vz0A:
10.20
1gtfO-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 7 GLY A 391
ALA A 382
THR A 410
SER A 385
 None
 0.81A 1gtnA-3vz0A:
undetectable
1gtnK-3vz0A:
undetectable		 1gtnA-3vz0A:
10.20
1gtnK-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 SER A 385
GLY A 391
ALA A 382
THR A 410
 None
 0.70A 1gtnE-3vz0A:
undetectable
1gtnF-3vz0A:
undetectable		 1gtnE-3vz0A:
10.20
1gtnF-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 SER A 385
GLY A 391
ALA A 382
THR A 410
 None
 0.72A 1gtnI-3vz0A:
undetectable
1gtnJ-3vz0A:
undetectable		 1gtnI-3vz0A:
10.20
1gtnJ-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 6 TYR A  96
VAL A 153
ILE A 126
LEU A 104
 None
 1.15A 1j96A-3vz0A:
undetectable		 1j96A-3vz0A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 9 PHE A 257
GLY A 332
ALA A 331
LEU A 281
LEU A 284
 None
 1.03A 1nr6A-3vz0A:
undetectable		 1nr6A-3vz0A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 GLY A 391
ALA A 382
THR A 410
SER A 385
 None
 0.68A 1utdI-3vz0A:
undetectable
1utdJ-3vz0A:
undetectable		 1utdI-3vz0A:
10.20
1utdJ-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 6 SER A 385
SER A 433
LEU A 389
GLY A 388
 None
 0.90A 2j2pA-3vz0A:
undetectable
2j2pC-3vz0A:
undetectable		 2j2pA-3vz0A:
19.34
2j2pC-3vz0A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 6 SER A 385
SER A 433
LEU A 389
GLY A 388
 None
 0.89A 2j2pD-3vz0A:
undetectable
2j2pF-3vz0A:
undetectable		 2j2pD-3vz0A:
19.34
2j2pF-3vz0A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_E_MTXE621_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 ALA A 143
LEU A  93
LEU A 171
LYS A 170
ILE A  86
 None
 0.90A 2oipE-3vz0A:
2.2		 2oipE-3vz0A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLP_A_TESA1921_1
(ANDROGEN RECEPTOR)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 11 GLN A 262
MET A 343
MET A 306
LEU A 316
THR A 319
 None
 1.36A 2ylpA-3vz0A:
undetectable		 2ylpA-3vz0A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 10 GLU A 344
GLY A 364
VAL A 263
ALA A 266
PHE A 257
 None
 1.29A 3a3yA-3vz0A:
undetectable		 3a3yA-3vz0A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 6 ILE A 201
LEU A  20
PHE A 186
MET A  26
 None
 1.14A 3adsA-3vz0A:
undetectable		 3adsA-3vz0A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		3 / 3 GLU A 313
LEU A 316
ASP A 317
 None
 0.43A 3ko0A-3vz0A:
undetectable		 3ko0A-3vz0A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		3 / 3 GLU A 313
LEU A 316
ASP A 317
 None
 0.41A 3ko0T-3vz0A:
undetectable		 3ko0T-3vz0A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 9 VAL A 369
PHE A 280
ALA A 287
THR A 289
VAL A 330
 None
 1.18A 3me6C-3vz0A:
undetectable		 3me6C-3vz0A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 9 VAL A 369
PHE A 280
ILE A 347
ALA A 287
THR A 289
 None
 1.21A 3me6C-3vz0A:
undetectable		 3me6C-3vz0A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 9 VAL A 369
PHE A 280
ALA A 287
THR A 289
VAL A 330
 None
 1.23A 3me6D-3vz0A:
undetectable		 3me6D-3vz0A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 9 VAL A 369
PHE A 280
ILE A 347
ALA A 287
THR A 289
 None
 1.21A 3me6D-3vz0A:
undetectable		 3me6D-3vz0A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 5 GLY A 233
ASP A 235
GLN A 262
MET A  75
 None
 1.38A 3qx3B-3vz0A:
undetectable		 3qx3B-3vz0A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_A_NIOA311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 9 ASP A 174
LEU A  60
HIS A  67
ALA A 175
PHE A 172
 None
 1.24A 3r2jA-3vz0A:
2.8		 3r2jA-3vz0A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_B_NIOB311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 11 ASP A 174
LEU A  60
HIS A  67
ALA A 175
PHE A 172
 None
 1.20A 3r2jB-3vz0A:
3.6		 3r2jB-3vz0A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_C_NIOC311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 ASP A 174
LEU A  60
HIS A  67
ALA A 175
PHE A 172
 None
 1.19A 3r2jC-3vz0A:
3.4		 3r2jC-3vz0A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_D_NIOD311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 11 ASP A 174
LEU A  60
HIS A  67
ALA A 175
PHE A 172
 None
 1.28A 3r2jD-3vz0A:
3.7		 3r2jD-3vz0A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_A_MTXA603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 ALA A 143
LEU A  93
LEU A 171
LYS A 170
ILE A  86
 None
 0.92A 4ky8A-3vz0A:
undetectable		 4ky8A-3vz0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_B_MTXB603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 ALA A 143
LEU A  93
LEU A 171
LYS A 170
ILE A  86
 None
 0.96A 4ky8B-3vz0A:
undetectable		 4ky8B-3vz0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_C_MTXC603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 ALA A 143
LEU A  93
LEU A 171
LYS A 170
ILE A  86
 None
 0.95A 4ky8C-3vz0A:
undetectable		 4ky8C-3vz0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 ALA A 143
LEU A  93
LEU A 171
LYS A 170
ILE A  86
 None
 0.95A 4ky8D-3vz0A:
undetectable		 4ky8D-3vz0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_E_MTXE603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 ALA A 143
LEU A  93
LEU A 171
LYS A 170
ILE A  86
 None
 0.93A 4ky8E-3vz0A:
undetectable		 4ky8E-3vz0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		3 / 3 GLY A 304
PRO A 305
GLN A 262
 None
 0.57A 4oltB-3vz0A:
undetectable		 4oltB-3vz0A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 6 ARG A  64
ALA A  68
ASP A  87
LEU A  79
 None
 0.94A 4ot2A-3vz0A:
undetectable		 4ot2A-3vz0A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_A_MTXA604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 ALA A 143
LEU A  93
LEU A 171
LYS A 170
ILE A  86
 None
 1.03A 4q0dA-3vz0A:
undetectable		 4q0dA-3vz0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_B_MTXB604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 ALA A 143
LEU A  93
LEU A 171
LYS A 170
ILE A  86
 None
 1.04A 4q0dB-3vz0A:
undetectable		 4q0dB-3vz0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_E_MTXE604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 ALA A 143
LEU A  93
LEU A 171
LYS A 170
ILE A  86
 None
 1.03A 4q0dE-3vz0A:
undetectable		 4q0dE-3vz0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		3 / 3 GLY A 304
PRO A 305
GLN A 262
 None
 0.56A 4qwpB-3vz0A:
undetectable		 4qwpB-3vz0A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 5 ARG A 338
GLY A 294
GLY A 304
PRO A 305
 None
 0.92A 4u9uB-3vz0A:
5.6		 4u9uB-3vz0A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 10 GLY A 213
ALA A 158
ILE A 129
PRO A 131
LEU A 206
 None
 1.02A 4xj7A-3vz0A:
2.2
4xj7B-3vz0A:
3.0		 4xj7A-3vz0A:
21.76
4xj7B-3vz0A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 11 PHE A 291
GLY A 261
GLY A 364
MET A 306
ILE A 362
 None
 1.49A 4zvmA-3vz0A:
3.2
4zvmB-3vz0A:
3.2		 4zvmA-3vz0A:
21.20
4zvmB-3vz0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 6 ALA A 392
ARG A 141
GLY A 428
THR A 207
GLU A 230
 None
 1.42A 5btgA-3vz0A:
undetectable
5btgB-3vz0A:
2.5
5btgC-3vz0A:
undetectable		 5btgA-3vz0A:
23.98
5btgB-3vz0A:
19.61
5btgC-3vz0A:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 SER A 385
GLY A 391
ALA A 382
THR A 410
 None
 0.69A 5eevL-3vz0A:
undetectable
5eevV-3vz0A:
undetectable		 5eevL-3vz0A:
10.20
5eevV-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 SER A 385
GLY A 391
ALA A 382
THR A 410
 None
 0.69A 5eewL-3vz0A:
undetectable
5eewV-3vz0A:
undetectable		 5eewL-3vz0A:
10.20
5eewV-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 SER A 385
GLY A 391
ALA A 382
THR A 410
 None
 0.69A 5eezL-3vz0A:
undetectable
5eezV-3vz0A:
undetectable		 5eezL-3vz0A:
10.20
5eezV-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 SER A 385
GLY A 391
ALA A 382
THR A 410
 None
 0.69A 5ef1L-3vz0A:
undetectable
5ef1V-3vz0A:
undetectable		 5ef1L-3vz0A:
10.20
5ef1V-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 SER A 385
GLY A 391
ALA A 382
THR A 410
 None
 0.69A 5ef2L-3vz0A:
undetectable
5ef2V-3vz0A:
undetectable		 5ef2L-3vz0A:
10.20
5ef2V-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 SER A 385
GLY A 391
ALA A 382
THR A 410
 None
 0.69A 5ef3L-3vz0A:
undetectable
5ef3V-3vz0A:
undetectable		 5ef3L-3vz0A:
10.20
5ef3V-3vz0A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 5 GLU A  74
GLU A  85
THR A  89
LEU A 171
 None
 1.18A 5hm8A-3vz0A:
2.8		 5hm8A-3vz0A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 5 GLU A  74
GLU A  85
THR A  89
LEU A 171
 None
 1.18A 5hm8B-3vz0A:
2.8		 5hm8B-3vz0A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 5 GLU A  74
GLU A  85
THR A  89
LEU A 171
 None
 1.18A 5hm8C-3vz0A:
2.8		 5hm8C-3vz0A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 5 GLU A  74
GLU A  85
THR A  89
LEU A 171
 None
 1.18A 5hm8D-3vz0A:
2.8		 5hm8D-3vz0A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 5 GLU A  74
GLU A  85
THR A  89
LEU A 171
 None
 1.18A 5hm8E-3vz0A:
3.9		 5hm8E-3vz0A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 5 GLU A  74
GLU A  85
THR A  89
LEU A 171
 None
 1.18A 5hm8F-3vz0A:
3.3		 5hm8F-3vz0A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 5 GLU A  74
GLU A  85
THR A  89
LEU A 171
 None
 1.13A 5hm8G-3vz0A:
3.9		 5hm8G-3vz0A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 5 GLU A  74
GLU A  85
THR A  89
LEU A 171
 None
 1.18A 5hm8H-3vz0A:
3.5		 5hm8H-3vz0A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 7 LEU A 389
SER A 385
ILE A 362
GLU A 361
 None
 0.93A 5n5dA-3vz0A:
6.0		 5n5dA-3vz0A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 6 ARG A 338
GLY A 304
PRO A 305
THR A 301
 None
 1.04A 5ny7A-3vz0A:
undetectable		 5ny7A-3vz0A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 SER A 385
ASN A 383
GLN A 407
SER A 433
GLY A 388
 None
 1.37A 5oj0A-3vz0A:
undetectable		 5oj0A-3vz0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		5 / 12 SER A 385
ASN A 383
SER A 433
GLY A 388
THR A 410
 None
 1.09A 5oj0A-3vz0A:
undetectable		 5oj0A-3vz0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 THR A  13
THR A   6
ARG A  16
GLN A 163
 None
 1.23A 5tzoA-3vz0A:
undetectable		 5tzoA-3vz0A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 THR A  13
THR A   6
ARG A  16
GLN A 163
 None
 1.25A 5tzoB-3vz0A:
undetectable		 5tzoB-3vz0A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 8 THR A  13
THR A   6
ARG A  16
GLN A 163
 None
 1.25A 5tzoC-3vz0A:
undetectable		 5tzoC-3vz0A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE
(Gluconobacter
oxydans) 		4 / 5 GLY A 233
ASP A 235
GLN A 262
MET A  75
 None
 1.44A 5zrfB-3vz0A:
undetectable		 5zrfB-3vz0A:
21.67