SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vza'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GC9_A_ACTA402_0 (DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL)	3vza	SPC24 PROTEIN (Gallus gallus)	3 / 3	LYS D 143 TYR D 142 ARG D 146	None	1.30A	4gc9A-3vzaD: undetectable	4gc9A-3vzaD: 12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTA_G_MFXG101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	3vza	UNCHARACTERIZED PROTEIN (Gallus gallus)	4 / 7	SER B 229 ASP B 174 GLY B 150 GLU B 147	None	0.90A	5btaA-3vzaB: undetectable 5btaC-3vzaB: undetectable 5btaD-3vzaB: undetectable	5btaA-3vzaB: 11.13 5btaC-3vzaB: 11.13 5btaD-3vzaB: 17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTF_F_GFNF101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	3vza	UNCHARACTERIZED PROTEIN (Gallus gallus)	4 / 7	SER B 229 ASP B 174 GLY B 150 GLU B 147	None	0.82A	5btfA-3vzaB: undetectable 5btfB-3vzaB: undetectable 5btfC-3vzaB: undetectable	5btfA-3vzaB: 11.13 5btfB-3vzaB: 17.23 5btfC-3vzaB: 11.13

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4GC9_A_ACTA402_0","DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL","3vza","SPC24 PROTEIN","Gallus gallus",3,"LYS D 143;TYR D 142;ARG D 146","None","1.30A","4gc9A-3vzaD:undetectable","4gc9A-3vzaD:12.71"],["5BTA_G_MFXG101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","3vza","UNCHARACTERIZED PROTEIN","Gallus gallus",4,"SER B 229;ASP B 174;GLY B 150;GLU B 147","None","0.90A","5btaA-3vzaB:undetectable;5btaC-3vzaB:undetectable;5btaD-3vzaB:undetectable","5btaA-3vzaB:11.13;5btaC-3vzaB:11.13;5btaD-3vzaB:17.23"],["5BTF_F_GFNF101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA GYRASE SUBUNIT A;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","3vza","UNCHARACTERIZED PROTEIN","Gallus gallus",4,"SER B 229;ASP B 174;GLY B 150;GLU B 147","None","0.82A","5btfA-3vzaB:undetectable;5btfB-3vzaB:undetectable;5btfC-3vzaB:undetectable","5btfA-3vzaB:11.13;5btfB-3vzaB:17.23;5btfC-3vzaB:11.13"]]