SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vzg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 3vzg ZYMOGEN GRANULE
MEMBRANE PROTEIN 16
(Homo
sapiens) 		3 / 3 LEU A 133
SER A  23
ASN A 136
 None
 0.58A 1bx4A-3vzgA:
undetectable		 1bx4A-3vzgA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3vzg ZYMOGEN GRANULE
MEMBRANE PROTEIN 16
(Homo
sapiens) 		5 / 10 PHE A 128
ALA A 130
LEU A  64
VAL A  54
ILE A 142
 None
 1.32A 1claA-3vzgA:
undetectable		 1claA-3vzgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 3vzg ZYMOGEN GRANULE
MEMBRANE PROTEIN 16
(Homo
sapiens) 		4 / 8 ILE A  61
LEU A 108
PHE A 120
ARG A  55
 None
 0.98A 2vdbA-3vzgA:
undetectable		 2vdbA-3vzgA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3vzg ZYMOGEN GRANULE
MEMBRANE PROTEIN 16
(Homo
sapiens) 		4 / 5 GLY A  34
ARG A 145
GLY A  31
GLU A  29
 MAN  A 202 ( 3.7A)
None
None
None
 1.26A 4z2eB-3vzgA:
undetectable
4z2eC-3vzgA:
undetectable		 4z2eB-3vzgA:
14.94
4z2eC-3vzgA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 3vzg ZYMOGEN GRANULE
MEMBRANE PROTEIN 16
(Homo
sapiens) 		5 / 7 VAL A  97
LEU A 139
ALA A 130
LEU A 108
LEU A 105
 None
 0.88A 5jq7A-3vzgA:
undetectable		 5jq7A-3vzgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 3vzg ZYMOGEN GRANULE
MEMBRANE PROTEIN 16
(Homo
sapiens) 		5 / 12 ILE A  49
VAL A  54
LEU A  88
SER A  73
LEU A 118
 None
 1.19A 6b52A-3vzgA:
undetectable		 6b52A-3vzgA:
20.87