SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vzh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		4 / 6 ILE A  63
ARG A  10
TYR A  95
PHE A  18
 None
 1.32A 1e73M-3vzhA:
undetectable		 1e73M-3vzhA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		5 / 7 PHE A 101
ASN A  55
PHE A  99
SER A 126
ARG A 132
 None
 1.14A 1rqpB-3vzhA:
undetectable		 1rqpB-3vzhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		5 / 8 PHE A 101
ASN A  55
PHE A  99
SER A 126
ARG A 132
 None
 1.16A 1rqpC-3vzhA:
undetectable		 1rqpC-3vzhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		5 / 8 PHE A 101
ASN A  55
PHE A  99
SER A 126
ARG A 132
 None
 1.15A 1rqpA-3vzhA:
undetectable		 1rqpA-3vzhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		5 / 8 PHE A 101
ASN A  55
PHE A  99
SER A 126
ARG A 132
 None
 1.14A 2v7uA-3vzhA:
undetectable		 2v7uA-3vzhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		5 / 7 PHE A 101
ASN A  55
PHE A  99
SER A 126
ARG A 132
 None
 1.13A 2v7uB-3vzhA:
undetectable		 2v7uB-3vzhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1300_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		5 / 9 PHE A 101
ASN A  55
PHE A  99
SER A 126
ARG A 132
 None
 1.14A 2v7uC-3vzhA:
0.0		 2v7uC-3vzhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		4 / 7 TYR A   2
ARG A   3
PHE A 101
PHE A   7
 None
 1.11A 2zseA-3vzhA:
undetectable		 2zseA-3vzhA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		4 / 6 TYR A   2
ARG A   3
PHE A 101
PHE A   7
 None
 1.18A 3af3A-3vzhA:
undetectable		 3af3A-3vzhA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		4 / 7 VAL A  94
ILE A  43
GLY A  42
ARG A  37
 None
 0.89A 3bjwB-3vzhA:
undetectable		 3bjwB-3vzhA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		4 / 7 VAL A  94
ILE A  43
GLY A  42
ARG A  37
 None
 0.80A 3bjwH-3vzhA:
undetectable		 3bjwH-3vzhA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		5 / 12 LEU A  40
GLY A 138
GLY A  13
ILE A  97
ILE A  43
 None
 0.81A 3s54A-3vzhA:
undetectable		 3s54A-3vzhA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		3 / 3 ARG A 132
ARG A 133
ILE A 122
 None
 0.81A 4b7qC-3vzhA:
undetectable		 4b7qC-3vzhA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		3 / 3 ASP A 113
ARG A 125
ARG A 132
 None
 0.88A 4x5iA-3vzhA:
undetectable		 4x5iA-3vzhA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		5 / 12 LEU A  40
GLY A 138
GLY A  13
ILE A  97
ILE A  43
 None
 0.84A 5e5jB-3vzhA:
undetectable		 5e5jB-3vzhA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 3vzh PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pyogenes) 		3 / 3 ASP A 113
ARG A 125
ARG A 132
 None
 0.99A 5eajB-3vzhA:
undetectable		 5eajB-3vzhA:
21.94