SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vzm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 8 ASP A 101
SER A 100
TYR A 105
HIS A 149
 None
 1.34A 2bteA-3vzmA:
undetectable		 2bteA-3vzmA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 8 ASP A 101
SER A 100
TYR A 105
HIS A 149
 None
 1.38A 2bteD-3vzmA:
undetectable		 2bteD-3vzmA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 5 ILE A 144
HIS A 149
TYR A  53
ARG A 132
 None
 1.25A 3b9mA-3vzmA:
undetectable		 3b9mA-3vzmA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		5 / 12 GLY A  70
VAL A  81
ALA A 165
LEU A 160
ILE A  77
 None
 1.04A 3ku1H-3vzmA:
undetectable		 3ku1H-3vzmA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		3 / 3 ASN A  52
TRP A 185
ASP A 101
 None
 0.88A 4a7tA-3vzmA:
undetectable
4a7tF-3vzmA:
undetectable		 4a7tA-3vzmA:
24.02
4a7tF-3vzmA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 4 ASN A  52
SER A  84
LEU A  66
THR A  50
 None
 1.40A 4an2A-3vzmA:
undetectable		 4an2A-3vzmA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 7 TYR A  65
TYR A  80
LEU A  68
PHE A 146
 None
 1.00A 4yv5A-3vzmA:
undetectable		 4yv5A-3vzmA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 7 TYR A  65
TYR A  80
LEU A  68
PHE A 146
 None
 1.06A 4yv5B-3vzmA:
undetectable		 4yv5B-3vzmA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		3 / 3 THR A 145
THR A  50
PHE A  48
 None
 0.86A 5cxvA-3vzmA:
undetectable		 5cxvA-3vzmA:
16.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 8 THR A  91
THR A 110
ARG A 112
GLN A 127
 None
None
DFX  A 201 (-3.9A)
DFX  A 201 (-4.3A)
 0.82A 5tzoA-3vzmA:
35.1		 5tzoA-3vzmA:
91.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		5 / 8 TYR A 108
THR A 110
ARG A 112
GLN A 127
TRP A 129
 None
None
DFX  A 201 (-3.9A)
DFX  A 201 (-4.3A)
None
 0.46A 5tzoA-3vzmA:
35.1		 5tzoA-3vzmA:
91.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		7 / 12 VAL A  37
TRP A  71
TYR A  80
PRO A 116
TRP A 129
TYR A 166
GLY A 173
 XYP  A 202 (-4.9A)
XYP  A 202 ( 4.9A)
None
DFX  A 201 (-3.9A)
None
XYP  A 202 (-4.7A)
None
 0.48A 5tzoA-3vzmA:
35.1		 5tzoA-3vzmA:
91.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		6 / 12 VAL A  37
TRP A  71
TYR A  80
TRP A 129
TYR A 166
GLY A 173
 XYP  A 202 (-4.9A)
XYP  A 202 ( 4.9A)
None
None
XYP  A 202 (-4.7A)
None
 0.58A 5tzoB-3vzmA:
35.0		 5tzoB-3vzmA:
91.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		3 / 3 ARG A 112
PRO A 116
TYR A 174
 DFX  A 201 (-3.9A)
DFX  A 201 (-3.9A)
None
 0.24A 5tzoB-3vzmA:
35.0		 5tzoB-3vzmA:
91.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		5 / 8 TYR A 108
THR A 110
ARG A 112
GLN A 127
TRP A 129
 None
None
DFX  A 201 (-3.9A)
DFX  A 201 (-4.3A)
None
 0.25A 5tzoB-3vzmA:
35.0		 5tzoB-3vzmA:
91.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		7 / 12 VAL A  37
TRP A  71
TYR A  80
PRO A 116
TRP A 129
TYR A 166
GLY A 173
 XYP  A 202 (-4.9A)
XYP  A 202 ( 4.9A)
None
DFX  A 201 (-3.9A)
None
XYP  A 202 (-4.7A)
None
 0.53A 5tzoC-3vzmA:
35.1		 5tzoC-3vzmA:
91.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 8 THR A  91
THR A 110
ARG A 112
GLN A 127
 None
None
DFX  A 201 (-3.9A)
DFX  A 201 (-4.3A)
 0.81A 5tzoC-3vzmA:
35.1		 5tzoC-3vzmA:
91.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		5 / 8 TYR A 108
THR A 110
ARG A 112
GLN A 127
TRP A 129
 None
None
DFX  A 201 (-3.9A)
DFX  A 201 (-4.3A)
None
 0.38A 5tzoC-3vzmA:
35.1		 5tzoC-3vzmA:
91.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 5 GLY A  86
THR A  87
SER A 177
SER A 176
 None
 0.93A 6jmjA-3vzmA:
undetectable		 6jmjA-3vzmA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 7 GLY A  86
THR A  87
SER A 177
SER A 176
 None
 0.89A 6jnhA-3vzmA:
undetectable		 6jnhA-3vzmA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3vzm ENDO-1,4-BETA-XYLANA
SE
(Bacillus
circulans) 		4 / 6 GLY A  86
THR A  87
SER A 177
SER A 176
 None
 0.90A 6jogA-3vzmA:
undetectable		 6jogA-3vzmA:
17.95