SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3vzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3vzu OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		3 / 3 ARG X  91
ASP X 104
ASN X 107
 None
ANP  X 401 (-4.0A)
None
 0.91A 1nbhA-3vzuX:
undetectable		 1nbhA-3vzuX:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3vzu OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		3 / 3 ARG X  91
ASP X 104
ASN X 107
 None
ANP  X 401 (-4.0A)
None
 0.88A 1nbhD-3vzuX:
undetectable		 1nbhD-3vzuX:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3vzu OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		4 / 6 LEU X 121
ALA X 236
ASP X 296
TYR X 295
 None
 1.27A 2dpzA-3vzuX:
undetectable		 2dpzA-3vzuX:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3vzu OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		3 / 3 ARG X 203
ASP X 101
GLN X  60
 None
 0.93A 3lcvB-3vzuX:
undetectable		 3lcvB-3vzuX:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WHY_A_SAMA504_0
(RADICAL SAM DOMAIN
PROTEIN)		 3vzu OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		5 / 11 TYR X 187
THR X  97
SER X 190
VAL X 222
VAL X 223
 None
 1.25A 5whyA-3vzuX:
0.0		 5whyA-3vzuX:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WHY_B_SAMB504_0
(RADICAL SAM DOMAIN
PROTEIN)		 3vzu OUTER MEMBRANE
PROTEIN
(Neisseria
meningitidis) 		5 / 10 TYR X 187
THR X  97
SER X 190
VAL X 222
VAL X 223
 None
 1.30A 5whyB-3vzuX:
undetectable		 5whyB-3vzuX:
21.69