SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 3w11 INSULIN RECEPTOR
DOMAINS L1-CR
(Homo
sapiens) 		5 / 11 LEU E  36
ILE E  13
ARG E  19
VAL E  94
LEU E  93
 None
 1.39A 3a9eB-3w11E:
undetectable		 3a9eB-3w11E:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3w11 INSULIN RECEPTOR
DOMAINS L1-CR
(Homo
sapiens) 		4 / 7 ASN E 148
LYS E 121
TYR E  67
LEU E  69
 None
 0.93A 4yv5B-3w11E:
undetectable		 4yv5B-3w11E:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 3w11 INSULIN RECEPTOR
DOMAINS L1-CR
(Homo
sapiens) 		5 / 12 VAL E 117
ILE E 119
LEU E  72
LEU E  61
LEU E  63
 None
 1.26A 5tiwA-3w11E:
undetectable		 5tiwA-3w11E:
19.76