SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w1e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		3 / 3 SER A  14
GLU A  15
GLU A  16
 None
 0.56A 1eqbD-3w1eA:
undetectable		 1eqbD-3w1eA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		3 / 3 SER A  14
GLU A  15
GLU A  16
 None
 0.57A 1eqbB-3w1eA:
undetectable		 1eqbB-3w1eA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		3 / 3 PHE A 141
ARG A 132
ASN A 131
 None
 0.90A 1xzxX-3w1eA:
undetectable		 1xzxX-3w1eA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		4 / 7 ILE A 266
LEU A 268
TYR A 170
THR A 208
 None
 1.04A 2zxwN-3w1eA:
undetectable
2zxwW-3w1eA:
undetectable		 2zxwN-3w1eA:
21.00
2zxwW-3w1eA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		5 / 11 ILE A 101
SER A 143
THR A 147
VAL A 144
GLY A 145
 None
 0.90A 3kw4A-3w1eA:
undetectable		 3kw4A-3w1eA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		4 / 6 PRO A 156
TYR A 170
VAL A 212
THR A 159
 None
 1.07A 3tneA-3w1eA:
undetectable		 3tneA-3w1eA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		4 / 6 ILE A 266
LEU A 268
TYR A 170
THR A 208
 None
 1.14A 3wg7A-3w1eA:
undetectable
3wg7J-3w1eA:
undetectable		 3wg7A-3w1eA:
21.00
3wg7J-3w1eA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		5 / 9 VAL A 175
LEU A 199
ALA A 198
PHE A 197
ILE A 106
 None
 1.17A 5om2A-3w1eA:
undetectable
5om2B-3w1eA:
undetectable		 5om2A-3w1eA:
10.83
5om2B-3w1eA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		5 / 12 GLY A 284
ILE A 266
ASP A 205
GLY A 206
ASP A 282
 None
 1.12A 5wwsB-3w1eA:
undetectable		 5wwsB-3w1eA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		3 / 3 ASN A 277
PRO A 338
GLN A 337
 None
 0.95A 6jnhA-3w1eA:
undetectable		 6jnhA-3w1eA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		3 / 3 ASN A 277
PRO A 338
GLN A 337
 None
 0.94A 6jogA-3w1eA:
undetectable		 6jogA-3w1eA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3w1e FLAGELLA BASAL-BODY
PROTEIN
(Vibrio
alginolyticus) 		4 / 6 ILE A 266
LEU A 268
TYR A 170
THR A 208
 None
 1.10A 6nmfN-3w1eA:
undetectable
6nmfW-3w1eA:
undetectable		 6nmfN-3w1eA:
21.00
6nmfW-3w1eA:
9.91