SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w1o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 3w1o DNA MIMIC PROTEIN
DMP12
(Neisseria
meningitidis) 		4 / 7 TYR A  47
THR A  40
VAL A  37
ILE A  39
 None
 0.97A 1p7rA-3w1oA:
undetectable		 1p7rA-3w1oA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3w1o DNA MIMIC PROTEIN
DMP12
(Neisseria
meningitidis) 		4 / 7 ILE A  39
TYR A  47
ILE A  44
GLN A  48
 None
 0.96A 3hgxA-3w1oA:
undetectable		 3hgxA-3w1oA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 3w1o DNA MIMIC PROTEIN
DMP12
(Neisseria
meningitidis) 		4 / 7 VAL A  56
PHE A 116
LEU A 104
ILE A 100
 None
 0.95A 3rfmA-3w1oA:
undetectable		 3rfmA-3w1oA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3w1o DNA MIMIC PROTEIN
DMP12
(Neisseria
meningitidis) 		4 / 6 TYR A  28
ASP A  71
HIS A 117
ILE A   8
 None
 1.18A 5ih0A-3w1oA:
undetectable		 5ih0A-3w1oA:
17.50