SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w25'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		6 / 12 GLY A  84
LEU A 125
VAL A 124
LEU A  56
ALA A  68
PHE A 128
 None
 1.37A 1gseB-3w25A:
undetectable		 1gseB-3w25A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		4 / 5 ILE A 186
ILE A 286
ILE A 191
MET A 201
 None
 0.76A 1zgyA-3w25A:
undetectable		 1zgyA-3w25A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 LEU A   9
ILE A  19
PHE A  13
ASP A 277
PHE A 291
 None
 1.20A 1zz1B-3w25A:
undetectable
1zz1C-3w25A:
undetectable		 1zz1B-3w25A:
21.05
1zz1C-3w25A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 LEU A  56
ILE A  71
ALA A  68
THR A 130
VAL A 124
 None
 1.07A 2g78A-3w25A:
undetectable		 2g78A-3w25A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		4 / 8 LEU A 154
LEU A 160
LEU A  88
ALA A 171
 None
 0.85A 2vcvP-3w25A:
undetectable		 2vcvP-3w25A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 VAL A 298
TRP A 300
TRP A 292
 None
XYP  A 402 (-4.1A)
XYP  A 401 (-4.2A)
 1.13A 2xdcA-3w25A:
undetectable
2xdcB-3w25A:
undetectable		 2xdcA-3w25A:
3.79
2xdcB-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 TRP A 292
VAL A 298
TRP A 300
 XYP  A 401 (-4.2A)
None
XYP  A 402 (-4.1A)
 1.14A 2xdcA-3w25A:
undetectable
2xdcB-3w25A:
undetectable		 2xdcA-3w25A:
3.79
2xdcB-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 TRP A 300
VAL A 298
TRP A 292
 XYP  A 402 (-4.1A)
None
XYP  A 401 (-4.2A)
 1.16A 2xdcA-3w25A:
undetectable
2xdcB-3w25A:
undetectable		 2xdcA-3w25A:
3.79
2xdcB-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 VAL A 298
TRP A 292
TRP A 300
 None
XYP  A 401 (-4.2A)
XYP  A 402 (-4.1A)
 1.01A 2xdcC-3w25A:
undetectable
2xdcD-3w25A:
undetectable		 2xdcC-3w25A:
3.79
2xdcD-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 TRP A 300
VAL A 298
TRP A 292
 XYP  A 402 (-4.1A)
None
XYP  A 401 (-4.2A)
 1.32A 2xdcC-3w25A:
undetectable
2xdcD-3w25A:
undetectable		 2xdcC-3w25A:
3.79
2xdcD-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 TRP A 300
VAL A 298
TRP A 292
 XYP  A 402 (-4.1A)
None
XYP  A 401 (-4.2A)
 1.33A 2xdcE-3w25A:
undetectable
2xdcF-3w25A:
undetectable		 2xdcE-3w25A:
3.79
2xdcF-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 VAL A 298
TRP A 292
TRP A 300
 None
XYP  A 401 (-4.2A)
XYP  A 402 (-4.1A)
 1.16A 2y5mA-3w25A:
undetectable
2y5mB-3w25A:
undetectable		 2y5mA-3w25A:
3.79
2y5mB-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 VAL A 298
TRP A 300
TRP A 292
 None
XYP  A 402 (-4.1A)
XYP  A 401 (-4.2A)
 1.14A 2y5mA-3w25A:
undetectable
2y5mB-3w25A:
undetectable		 2y5mA-3w25A:
3.79
2y5mB-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		4 / 4 VAL A  23
TRP A 300
VAL A 298
TRP A 292
 None
XYP  A 402 (-4.1A)
None
XYP  A 401 (-4.2A)
 1.36A 2y5mA-3w25A:
undetectable
2y5mB-3w25A:
undetectable		 2y5mA-3w25A:
3.79
2y5mB-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 TRP A 300
VAL A 298
TRP A 292
 XYP  A 402 (-4.1A)
None
XYP  A 401 (-4.2A)
 1.30A 2y5mE-3w25A:
undetectable
2y5mF-3w25A:
undetectable		 2y5mE-3w25A:
3.79
2y5mF-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 VAL A 298
TRP A 292
TRP A 300
 None
XYP  A 401 (-4.2A)
XYP  A 402 (-4.1A)
 1.17A 2y6nA-3w25A:
undetectable
2y6nB-3w25A:
undetectable		 2y6nA-3w25A:
3.79
2y6nB-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 VAL A 298
TRP A 300
TRP A 292
 None
XYP  A 402 (-4.1A)
XYP  A 401 (-4.2A)
 1.13A 2y6nA-3w25A:
undetectable
2y6nB-3w25A:
undetectable		 2y6nA-3w25A:
3.79
2y6nB-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 TRP A 292
VAL A 298
TRP A 300
 XYP  A 401 (-4.2A)
None
XYP  A 402 (-4.1A)
 1.12A 2y6nA-3w25A:
undetectable
2y6nB-3w25A:
undetectable		 2y6nA-3w25A:
3.79
2y6nB-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 TRP A 300
VAL A 298
TRP A 292
 XYP  A 402 (-4.1A)
None
XYP  A 401 (-4.2A)
 1.30A 2y6nC-3w25A:
undetectable
2y6nD-3w25A:
undetectable		 2y6nC-3w25A:
3.79
2y6nD-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 TRP A 300
VAL A 298
TRP A 292
 XYP  A 402 (-4.1A)
None
XYP  A 401 (-4.2A)
 1.31A 2y6nE-3w25A:
undetectable
2y6nF-3w25A:
undetectable		 2y6nE-3w25A:
3.79
2y6nF-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 ASP A 297
SER A 295
ARG A  27
 None
 0.99A 3loqA-3w25A:
undetectable		 3loqA-3w25A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 11 PRO A  33
LEU A  28
VAL A  23
ALA A  22
THR A  38
 None
 1.19A 3n23C-3w25A:
undetectable		 3n23C-3w25A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 VAL A 298
TRP A 292
TRP A 300
 None
XYP  A 401 (-4.2A)
XYP  A 402 (-4.1A)
 0.99A 3zq8A-3w25A:
undetectable
3zq8B-3w25A:
undetectable		 3zq8A-3w25A:
3.79
3zq8B-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 VAL A 298
TRP A 300
TRP A 292
 None
XYP  A 402 (-4.1A)
XYP  A 401 (-4.2A)
 1.30A 3zq8A-3w25A:
undetectable
3zq8B-3w25A:
undetectable		 3zq8A-3w25A:
3.79
3zq8B-3w25A:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1480_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		4 / 4 LYS A 239
GLU A 282
ILE A 237
SER A 236
 None
 1.49A 4acaC-3w25A:
3.1		 4acaC-3w25A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1480_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		4 / 4 LYS A 239
GLU A 282
ILE A 237
SER A 236
 None
 1.46A 4acbC-3w25A:
3.0		 4acbC-3w25A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 ILE A 186
PHE A 185
ILE A 218
VAL A 245
ILE A 247
 None
 0.95A 4ax8A-3w25A:
undetectable		 4ax8A-3w25A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 ILE A 186
PHE A 185
ILE A 218
VAL A 245
ILE A 247
 None
 0.93A 4azvA-3w25A:
undetectable		 4azvA-3w25A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 ASN A  29
ALA A  35
THR A  38
LEU A  45
 None
 1.01A 4ejgD-3w25A:
undetectable		 4ejgD-3w25A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 MET A 201
LEU A 204
ILE A 186
ILE A 215
LEU A 243
 None
 1.11A 4j24A-3w25A:
undetectable		 4j24A-3w25A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 MET A 201
LEU A 204
ILE A 186
ILE A 215
LEU A 243
 None
 1.10A 4j24B-3w25A:
undetectable		 4j24B-3w25A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 SER A 299
ASP A 296
GLN A 268
 None
 0.76A 4oltA-3w25A:
undetectable
4oltB-3w25A:
undetectable		 4oltA-3w25A:
23.45
4oltB-3w25A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 GLN A 268
SER A 299
ASP A 296
 None
 0.72A 4qwpA-3w25A:
undetectable
4qwpB-3w25A:
undetectable		 4qwpA-3w25A:
23.45
4qwpB-3w25A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		3 / 3 ILE A 218
ILE A 237
MET A 201
 None
 0.65A 5i9yA-3w25A:
undetectable		 5i9yA-3w25A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 MET A 201
ILE A 191
VAL A 205
VAL A 245
GLY A 140
 None
 1.08A 5igjA-3w25A:
undetectable		 5igjA-3w25A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W8A_A_SAMA300_0
(AUTOINDUCER SYNTHASE)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 12 LEU A 278
MET A 220
VAL A 249
SER A 236
ILE A 247
 None
 1.35A 5w8aA-3w25A:
undetectable		 5w8aA-3w25A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 7 PHE A  17
ILE A  19
PHE A 310
LEU A   9
ALA A 319
 None
 1.40A 6b5vA-3w25A:
undetectable
6b5vC-3w25A:
undetectable		 6b5vA-3w25A:
12.20
6b5vC-3w25A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 7 PHE A  17
ILE A  19
PHE A 310
LEU A   9
ALA A 319
 None
 1.39A 6b5vC-3w25A:
undetectable
6b5vD-3w25A:
undetectable		 6b5vC-3w25A:
12.20
6b5vD-3w25A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		5 / 7 ALA A 319
PHE A  17
ILE A  19
PHE A 310
LEU A   9
 None
 1.40A 6b5vB-3w25A:
undetectable
6b5vD-3w25A:
undetectable		 6b5vB-3w25A:
12.20
6b5vD-3w25A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 3w25 GLYCOSIDE HYDROLASE
FAMILY 10
(Thermoanaerobact
erium
saccharolyticum) 		4 / 6 GLU A 169
LYS A 170
PHE A 172
PRO A 214
 None
 1.39A 6fgdA-3w25A:
undetectable		 6fgdA-3w25A:
20.18