SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w2w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3w2w CRISPR SYSTEM CMR
SUBUNIT CMR3
(Pyrococcus
furiosus) 		5 / 12 SER B 190
VAL B   4
ILE B 178
VAL B 206
LEU B 195
 None
 0.99A 1qhyA-3w2wB:
undetectable		 1qhyA-3w2wB:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 3w2w CRISPR SYSTEM CMR
SUBUNIT CMR3
(Pyrococcus
furiosus) 		4 / 7 VAL B   4
THR B   5
PHE B   6
THR B   7
 None
 1.24A 2kotA-3w2wB:
undetectable		 2kotA-3w2wB:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 3w2w CRISPR SYSTEM CMR
SUBUNIT CMR3
(Pyrococcus
furiosus) 		4 / 8 VAL B   4
THR B   5
PHE B   6
THR B   7
 None
 1.03A 2kotB-3w2wB:
undetectable		 2kotB-3w2wB:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 3w2w CRISPR SYSTEM CMR
SUBUNIT CMR3
(Pyrococcus
furiosus) 		5 / 12 ARG B  77
TYR B 175
ASP B  10
ARG B 146
PHE B 168
 None
 1.39A 3a27A-3w2wB:
undetectable		 3a27A-3w2wB:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3w2w CRISPR SYSTEM CMR
SUBUNIT CMR3
(Pyrococcus
furiosus) 		4 / 7 ILE B 320
LEU B 227
GLY B 318
GLY B 319
 None
 0.82A 5a06A-3w2wB:
undetectable		 5a06A-3w2wB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3w2w CRISPR SYSTEM CMR
SUBUNIT CMR3
(Pyrococcus
furiosus) 		4 / 7 ILE B 320
LEU B 227
GLY B 318
GLY B 319
 None
 0.80A 5a06B-3w2wB:
undetectable		 5a06B-3w2wB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3w2w CRISPR SYSTEM CMR
SUBUNIT CMR3
(Pyrococcus
furiosus) 		4 / 7 ILE B 320
LEU B 227
GLY B 318
GLY B 319
 None
 0.82A 5a06C-3w2wB:
undetectable		 5a06C-3w2wB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3w2w CRISPR SYSTEM CMR
SUBUNIT CMR3
(Pyrococcus
furiosus) 		4 / 7 ILE B 320
LEU B 227
GLY B 318
GLY B 319
 None
 0.82A 5a06E-3w2wB:
undetectable		 5a06E-3w2wB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3w2w CRISPR SYSTEM CMR
SUBUNIT CMR3
(Pyrococcus
furiosus) 		4 / 7 ILE B 320
LEU B 227
GLY B 318
GLY B 319
 None
 0.83A 5a06F-3w2wB:
undetectable		 5a06F-3w2wB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3w2w CRISPR SYSTEM CMR
SUBUNIT CMR3
(Pyrococcus
furiosus) 		4 / 6 PHE B 290
SER B 287
LEU B 258
LEU B 257
 None
 1.13A 5dzke-3w2wB:
undetectable
5dzks-3w2wB:
undetectable		 5dzke-3w2wB:
19.82
5dzks-3w2wB:
15.38