SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w3e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 11 PHE A  35
ILE A 116
ALA A 153
LEU A 154
ALA A  38
 None
 1.06A 1jb0B-3w3eA:
undetectable		 1jb0B-3w3eA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		4 / 7 PHE A  61
ALA A 153
PHE A 150
SER A 149
 None
 1.29A 1lqtA-3w3eA:
undetectable		 1lqtA-3w3eA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		4 / 7 PHE A  61
ALA A 153
PHE A 150
SER A 149
 None
 1.30A 1lquA-3w3eA:
undetectable		 1lquA-3w3eA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		3 / 3 ALA A 153
THR A  65
PHE A  42
 None
 0.55A 2c6nB-3w3eA:
undetectable		 2c6nB-3w3eA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		3 / 3 TYR A 124
VAL A 142
THR A 119
 None
 0.56A 2ygnA-3w3eA:
undetectable		 2ygnA-3w3eA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		4 / 7 ALA A 127
ALA A 126
ALA A 130
GLN A 161
 None
 0.76A 3a2qA-3w3eA:
undetectable		 3a2qA-3w3eA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 12 VAL A  88
PHE A  61
LEU A  62
ALA A  34
SER A 149
 None
 1.34A 3apvA-3w3eA:
undetectable		 3apvA-3w3eA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 12 VAL A  88
PHE A  61
LEU A  62
ALA A  34
SER A 149
 None
 1.37A 3apvB-3w3eA:
undetectable		 3apvB-3w3eA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 12 PHE A  29
VAL A  88
PHE A  61
ALA A  34
SER A 149
 None
 1.49A 3apwA-3w3eA:
undetectable		 3apwA-3w3eA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		4 / 4 ILE A 197
PHE A 156
ILE A 196
THR A  65
 None
 1.13A 3ia4A-3w3eA:
undetectable		 3ia4A-3w3eA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		4 / 4 PRO A 115
THR A  65
GLY A  46
THR A  47
 None
 1.13A 3ib1A-3w3eA:
undetectable		 3ib1A-3w3eA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 11 PHE A  35
ILE A 116
ALA A 153
LEU A 154
ALA A  38
 None
 1.06A 3pcqB-3w3eA:
undetectable		 3pcqB-3w3eA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_M_CLMM221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 10 SER A  66
TYR A  85
VAL A   3
PHE A  45
PHE A  12
 None
 1.41A 3u9fM-3w3eA:
undetectable
3u9fN-3w3eA:
undetectable		 3u9fM-3w3eA:
22.47
3u9fN-3w3eA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_O_CLMO221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 11 PHE A  12
SER A  66
TYR A  85
VAL A   3
PHE A  45
 None
 1.46A 3u9fM-3w3eA:
undetectable
3u9fO-3w3eA:
undetectable		 3u9fM-3w3eA:
22.47
3u9fO-3w3eA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		3 / 3 TYR A 110
ARG A  96
SER A 109
 None
 1.05A 4dr2I-3w3eA:
undetectable
4dr2J-3w3eA:
0.4		 4dr2I-3w3eA:
20.18
4dr2J-3w3eA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		4 / 5 THR A 152
GLY A 114
VAL A  88
TYR A 124
 None
 1.16A 4grkA-3w3eA:
undetectable		 4grkA-3w3eA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		4 / 8 VAL A 192
ASN A 232
GLN A  64
ILE A 171
 None
 1.06A 4iilA-3w3eA:
undetectable		 4iilA-3w3eA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		3 / 3 TYR A 110
ARG A  96
SER A 109
 None
 0.84A 4khpI-3w3eA:
undetectable
4khpJ-3w3eA:
undetectable		 4khpI-3w3eA:
19.82
4khpJ-3w3eA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 12 PHE A  61
ALA A  59
PHE A  45
LEU A 154
GLY A   8
 None
 1.28A 4kykA-3w3eA:
undetectable
4kykB-3w3eA:
undetectable		 4kykA-3w3eA:
24.89
4kykB-3w3eA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		3 / 3 TYR A 110
ARG A  96
SER A 109
 None
 1.10A 4lf7I-3w3eA:
undetectable
4lf7J-3w3eA:
0.3		 4lf7I-3w3eA:
20.18
4lf7J-3w3eA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		3 / 3 TYR A 110
ARG A  96
SER A 109
 None
 1.10A 4lf8I-3w3eA:
undetectable
4lf8J-3w3eA:
0.3		 4lf8I-3w3eA:
20.18
4lf8J-3w3eA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_B_ERYB501_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 11 ASN A  52
VAL A 227
TYR A 218
ASN A 173
ALA A  60
 None
 1.45A 4m83B-3w3eA:
undetectable		 4m83B-3w3eA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 11 ASP A 213
TYR A 221
TYR A  81
GLY A  71
GLY A  79
 None
 1.26A 4mm9A-3w3eA:
undetectable		 4mm9A-3w3eA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 10 ASP A 213
TYR A 221
TYR A  81
GLY A  71
GLY A  79
 None
 1.28A 4mmcA-3w3eA:
undetectable		 4mmcA-3w3eA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		4 / 7 ILE A   7
GLY A   8
PHE A  29
ASP A  13
 None
 1.13A 5hieA-3w3eA:
undetectable		 5hieA-3w3eA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 12 PHE A  35
ILE A 116
ALA A 153
LEU A 154
ALA A  38
 None
 1.01A 5oy02-3w3eA:
undetectable		 5oy02-3w3eA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3w3e COTYLEDONEOUS
YIELDIN-LIKE PROTEIN
(Vigna
unguiculata) 		5 / 10 PHE A  35
ILE A 116
ALA A 153
LEU A 154
ALA A  38
 None
 1.03A 5oy0b-3w3eA:
undetectable		 5oy0b-3w3eA:
14.11