SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w40'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 3w40 PHOSPHOSERINE
PHOSPHATASE RSBX
(Bacillus
subtilis) 		5 / 11 GLY A  45
ALA A  88
GLY A 108
ALA A  41
ILE A  59
 None
 1.05A 2b60B-3w40A:
undetectable		 2b60B-3w40A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 3w40 PHOSPHOSERINE
PHOSPHATASE RSBX
(Bacillus
subtilis) 		5 / 12 VAL A  42
ALA A  41
GLY A 108
ASP A  27
THR A 155
 None
None
None
MG  A 201 ( 4.6A)
None
 1.21A 4mm8A-3w40A:
undetectable		 4mm8A-3w40A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 3w40 PHOSPHOSERINE
PHOSPHATASE RSBX
(Bacillus
subtilis) 		3 / 3 TYR A 123
PRO A 126
LEU A 125
 None
 0.91A 6beoA-3w40A:
undetectable		 6beoA-3w40A:
9.64