SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 5 GLU A 184
THR A 186
HIS A 213
LEU A 367
 None
 1.24A 1d4fC-3w4rA:
undetectable		 1d4fC-3w4rA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		7 / 9 TYR A  30
PHE A  61
GLY A 106
ASP A 146
MET A 215
ASP A 218
TRP A 372
 None
 1.03A 1e9lA-3w4rA:
53.8		 1e9lA-3w4rA:
28.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		7 / 9 TYR A  30
PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
 None
 0.84A 1e9lA-3w4rA:
53.8		 1e9lA-3w4rA:
28.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 1jffB-3w4rA:
undetectable		 1jffB-3w4rA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A  85
LEU A 143
GLY A 142
PHE A 140
ALA A 187
 None
 1.17A 1ju6A-3w4rA:
undetectable		 1ju6A-3w4rA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		10 / 11 TYR A  30
PHE A  61
GLY A 106
ASP A 146
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 None
 0.62A 2a3aA-3w4rA:
11.1		 2a3aA-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		9 / 11 TYR A  30
PHE A  61
GLY A 106
TRP A 107
ASP A 146
GLU A 148
MET A 215
TYR A 217
TRP A 372
 None
 0.70A 2a3aA-3w4rA:
11.1		 2a3aA-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		3 / 3 TRP A 107
GLU A 148
TYR A 149
 None
 0.47A 2a3aA-3w4rA:
11.1		 2a3aA-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		8 / 9 PHE A  61
GLY A 106
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 None
 0.50A 2a3aB-3w4rA:
10.4		 2a3aB-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1433_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 5 TRP A 107
TYR A 149
MET A 215
ASP A 218
 None
 0.70A 2a3bA-3w4rA:
44.0		 2a3bA-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		8 / 11 PHE A  61
GLY A 106
TRP A 107
ASP A 146
GLU A 148
MET A 215
TYR A 217
TRP A 372
 None
 0.81A 2a3bA-3w4rA:
44.0		 2a3bA-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		9 / 11 PHE A  61
GLY A 106
TRP A 107
ASP A 146
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 None
 0.65A 2a3bA-3w4rA:
44.0		 2a3bA-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		8 / 11 TYR A  30
PHE A  61
GLY A 106
ASP A 146
GLU A 148
MET A 215
TYR A 217
TRP A 372
 None
 0.77A 2a3bA-3w4rA:
44.0		 2a3bA-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		9 / 11 TYR A  30
PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 None
 0.65A 2a3bA-3w4rA:
44.0		 2a3bA-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		8 / 10 PHE A  61
GLY A 106
ASP A 146
GLU A 148
MET A 215
TYR A 217
ASP A 218
TRP A 372
 None
 0.70A 2a3bB-3w4rA:
11.0		 2a3bB-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		8 / 10 PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 None
 0.49A 2a3bB-3w4rA:
11.0		 2a3bB-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		9 / 12 TYR A  30
TRP A  34
PHE A  61
GLY A 106
ASP A 146
GLU A 148
MET A 215
TYR A 217
TRP A 372
 None
 0.85A 2a3cA-3w4rA:
11.2		 2a3cA-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		10 / 12 TYR A  30
TRP A  34
PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 None
 0.68A 2a3cA-3w4rA:
11.2		 2a3cA-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		9 / 12 TRP A  34
PHE A  61
GLY A 106
ASP A 146
GLU A 148
MET A 215
TYR A 217
ASP A 218
TRP A 372
 None
 0.72A 2a3cB-3w4rA:
10.8		 2a3cB-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		9 / 12 TRP A  34
PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 None
 0.50A 2a3cB-3w4rA:
10.8		 2a3cB-3w4rA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 2hxfB-3w4rA:
2.6		 2hxfB-3w4rA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 2hxhB-3w4rA:
2.6		 2hxhB-3w4rA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 2p4nB-3w4rA:
2.8		 2p4nB-3w4rA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		6 / 9 TYR A  30
PHE A  61
GLY A 106
ASP A 146
TYR A 217
TRP A 372
 None
 0.91A 2uy4A-3w4rA:
19.6		 2uy4A-3w4rA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		6 / 9 TYR A  30
PHE A  61
GLY A 106
GLU A 148
TYR A 217
TRP A 372
 None
 0.45A 2uy4A-3w4rA:
19.6		 2uy4A-3w4rA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 2wbeB-3w4rA:
2.6		 2wbeB-3w4rA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A  28
THR A 262
ASN A 263
VAL A 402
ALA A  25
 None
 1.28A 2x2iC-3w4rA:
6.9		 2x2iC-3w4rA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		6 / 11 TYR A  30
PHE A  61
GLY A 106
ASP A 146
TYR A 217
TRP A 372
 None
 1.04A 2xtkA-3w4rA:
21.0		 2xtkA-3w4rA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		6 / 11 TYR A  30
PHE A  61
GLY A 106
GLU A 148
TYR A 217
TRP A 372
 None
 0.77A 2xtkA-3w4rA:
21.0		 2xtkA-3w4rA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		6 / 10 TYR A  30
PHE A  61
GLY A 106
ASP A 146
TYR A 217
TRP A 372
 None
 1.01A 2xtkB-3w4rA:
21.0		 2xtkB-3w4rA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		6 / 10 TYR A  30
PHE A  61
GLY A 106
GLU A 148
TYR A 217
TRP A 372
 None
 0.63A 2xtkB-3w4rA:
21.0		 2xtkB-3w4rA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 8 VAL A 229
ASP A 239
GLY A 334
HIS A 238
 None
 0.91A 3af0A-3w4rA:
undetectable		 3af0A-3w4rA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 6 TRP A 107
ASP A 218
TRP A 223
ARG A 274
 None
 0.70A 3arqA-3w4rA:
41.0		 3arqA-3w4rA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 7 TRP A 107
ASP A 218
TRP A 223
ARG A 274
 None
 0.74A 3arrA-3w4rA:
41.1		 3arrA-3w4rA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 3dcoB-3w4rA:
2.8		 3dcoB-3w4rA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.18A 3edlB-3w4rA:
2.9		 3edlB-3w4rA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		10 / 11 PHE A  61
GLY A 106
TRP A 107
ASP A 146
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 None
 0.59A 3g6mA-3w4rA:
10.2		 3g6mA-3w4rA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		10 / 11 TYR A  30
PHE A  61
GLY A 106
ASP A 146
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 None
 0.67A 3g6mA-3w4rA:
10.2		 3g6mA-3w4rA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 5 TRP A 107
TYR A 149
MET A 215
ASP A 218
TRP A 223
 None
 0.67A 3g6mA-3w4rA:
10.2		 3g6mA-3w4rA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 11 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
 0.99A 3g88A-3w4rA:
undetectable		 3g88A-3w4rA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 11 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
 0.98A 3g88B-3w4rA:
undetectable		 3g88B-3w4rA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
 0.99A 3g89A-3w4rA:
undetectable		 3g89A-3w4rA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 11 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
 0.99A 3g89B-3w4rA:
undetectable		 3g89B-3w4rA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
 0.99A 3g8bA-3w4rA:
undetectable		 3g8bA-3w4rA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
 0.98A 3g8bB-3w4rA:
undetectable		 3g8bB-3w4rA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.16A 3iz0B-3w4rA:
undetectable		 3iz0B-3w4rA:
19.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQV_A_GCSA501_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		6 / 11 PHE A  61
GLY A 106
ASP A 146
TYR A 217
TYR A 272
TRP A 372
 None
 0.78A 3wqvA-3w4rA:
69.8		 3wqvA-3w4rA:
72.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQV_A_GCSA501_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		10 / 11 PHE A  61
GLY A 106
TRP A 107
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
ARG A 274
TRP A 372
 None
 0.25A 3wqvA-3w4rA:
69.8		 3wqvA-3w4rA:
72.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQV_A_GCSA502_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 4 TRP A  34
GLY A 106
TRP A 107
ALA A 108
 None
 0.19A 3wqvA-3w4rA:
47.5		 3wqvA-3w4rA:
72.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQW_A_GCSA501_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A  61
ASP A 146
TYR A 217
TYR A 272
TRP A 372
 None
 0.82A 3wqwA-3w4rA:
70.2		 3wqwA-3w4rA:
72.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQW_A_GCSA501_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		10 / 11 PHE A  61
GLY A 106
TRP A 107
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
ARG A 274
TRP A 372
 None
 0.23A 3wqwA-3w4rA:
70.2		 3wqwA-3w4rA:
72.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQW_A_GCSA502_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 5 TRP A  34
GLY A 106
TRP A 107
ALA A 108
PHE A 309
 None
 0.21A 3wqwA-3w4rA:
70.2		 3wqwA-3w4rA:
72.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		3 / 3 TYR A 272
HIS A 230
ARG A 274
 None
 1.22A 4e7bC-3w4rA:
0.5		 4e7bC-3w4rA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		3 / 3 LYS A 164
TYR A 167
ARG A 124
 None
 1.00A 4gc9A-3w4rA:
undetectable		 4gc9A-3w4rA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		3 / 3 ASP A 375
TYR A  44
TRP A  34
 None
 1.30A 4p7nA-3w4rA:
18.8		 4p7nA-3w4rA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 8 HIS A 230
GLU A 349
ARG A 220
PRO A 337
 None
 1.19A 4uhxA-3w4rA:
undetectable		 4uhxA-3w4rA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 8 HIS A 230
GLU A 349
ARG A 220
PRO A 337
 None
 1.19A 4uhxA-3w4rA:
undetectable		 4uhxA-3w4rA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 5 LEU A 172
ALA A 187
VAL A 102
ILE A  58
 None
 0.95A 4xe3B-3w4rA:
undetectable		 4xe3B-3w4rA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 7 GLU A  66
GLY A 110
SER A 112
GLY A 156
 None
 0.92A 5e26A-3w4rA:
undetectable
5e26B-3w4rA:
1.3		 5e26A-3w4rA:
21.14
5e26B-3w4rA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 6 TRP A 310
GLY A 308
THR A 307
SER A 275
 None
 1.01A 5ewuA-3w4rA:
1.9		 5ewuA-3w4rA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		3 / 3 TRP A 107
GLU A 148
ASP A 218
 None
 0.41A 5gqbA-3w4rA:
43.0		 5gqbA-3w4rA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		8 / 8 PHE A  61
GLY A 106
TRP A 107
GLU A 148
TYR A 217
ASP A 218
ARG A 274
TRP A 372
 None
 0.54A 5gqbA-3w4rA:
43.0		 5gqbA-3w4rA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		4 / 5 GLU A  66
GLY A 110
SER A 112
GLY A 156
 None
 0.88A 5kprA-3w4rA:
1.0		 5kprA-3w4rA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		3 / 3 GLU A 244
TYR A 243
ARG A 220
 None
 0.76A 5uunB-3w4rA:
undetectable		 5uunB-3w4rA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 10 LEU A 145
VAL A 128
VAL A 118
TYR A 114
LEU A 143
 None
 1.44A 6bsgA-3w4rA:
undetectable		 6bsgA-3w4rA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 10 LEU A 145
VAL A 128
VAL A 118
TYR A 114
LEU A 143
 None
 1.47A 6bsiA-3w4rA:
undetectable		 6bsiA-3w4rA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3w4r CHITINASE
(Ostrinia
furnacalis) 		5 / 10 LEU A 145
VAL A 128
VAL A 118
TYR A 114
LEU A 143
 None
 1.43A 6bsjA-3w4rA:
undetectable		 6bsjA-3w4rA:
10.64