SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w5f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 6 TYR A 310
GLY A 293
GLY A 254
SER A  45
 None
None
None
CL  A 807 (-3.0A)
 0.78A 1eswA-3w5fA:
8.1		 1eswA-3w5fA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 PHE A 126
TRP A  77
GLU A  81
 None
 1.15A 1mogA-3w5fA:
undetectable		 1mogA-3w5fA:
6.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 11 ALA A  63
GLY A 293
HIS A 292
GLY A  44
ILE A  71
 None
 1.03A 1pg2A-3w5fA:
undetectable		 1pg2A-3w5fA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 TRP A 129
VAL A 128
PRO A 127
 None
 1.00A 1rg1A-3w5fA:
undetectable		 1rg1A-3w5fA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 TRP A 129
VAL A 128
PRO A 127
 None
 1.00A 1rh0A-3w5fA:
undetectable		 1rh0A-3w5fA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 PHE A 232
TYR A 312
TYR A 256
 None
 1.01A 1x70B-3w5fA:
undetectable		 1x70B-3w5fA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 6 LEU A 316
LYS A  62
LEU A  59
PRO A 631
 None
 1.05A 2dqyC-3w5fA:
undetectable		 2dqyC-3w5fA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 12 SER A 540
ASN A 556
ALA A 496
VAL A 128
TYR A 132
 None
EPE  A 805 (-3.4A)
EPE  A 805 ( 4.4A)
None
None
 1.42A 2gl0D-3w5fA:
undetectable
2gl0E-3w5fA:
undetectable		 2gl0D-3w5fA:
13.01
2gl0E-3w5fA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 12 TRP A 255
PHE A 232
ILE A 271
TYR A 233
ASP A 311
 None
None
None
ARG  A 806 (-4.5A)
None
 1.33A 2iyfB-3w5fA:
undetectable		 2iyfB-3w5fA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 4 SER A 301
GLY A 298
HIS A 292
ASP A  58
 None
 1.25A 2oxtC-3w5fA:
undetectable		 2oxtC-3w5fA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 5 VAL A 157
VAL A 211
GLY A 210
TRP A 213
 None
None
CL  A 808 (-3.3A)
None
 0.97A 2p2fA-3w5fA:
1.2		 2p2fA-3w5fA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 11 ALA A  63
GLY A 293
HIS A 292
GLY A  44
ILE A  71
 None
 1.00A 2x1lA-3w5fA:
3.6		 2x1lA-3w5fA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 12 ALA A  63
GLY A 293
HIS A 292
GLY A  44
ILE A  71
 None
 1.03A 2x1lB-3w5fA:
undetectable		 2x1lB-3w5fA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 11 ALA A  63
GLY A 293
HIS A 292
GLY A  44
ILE A  71
 None
 1.02A 2x1lC-3w5fA:
undetectable		 2x1lC-3w5fA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 SER A 542
GLU A 456
ASP A 463
 None
 0.84A 2zthA-3w5fA:
2.6		 2zthA-3w5fA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 12 GLU A 250
PHE A 285
TYR A  74
ASN A 180
VAL A 117
 EPE  A 804 (-3.8A)
None
CL  A 807 (-4.2A)
None
None
 1.48A 3bjmB-3w5fA:
2.9		 3bjmB-3w5fA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 SER A 542
GLU A 456
ASP A 463
 None
 0.87A 3bwmA-3w5fA:
undetectable		 3bwmA-3w5fA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 SER A 542
GLU A 456
ASP A 463
 None
 0.81A 3bwyA-3w5fA:
undetectable		 3bwyA-3w5fA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 ARG A 653
VAL A 584
THR A 461
 None
 0.84A 3k4vA-3w5fA:
undetectable		 3k4vA-3w5fA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 12 LEU A 545
PHE A 123
GLY A 558
LEU A 560
GLU A 456
 None
 1.11A 3tbgA-3w5fA:
undetectable		 3tbgA-3w5fA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 12 LEU A 545
PHE A 123
GLY A 558
LEU A 560
GLU A 456
 None
 1.06A 3tbgB-3w5fA:
undetectable		 3tbgB-3w5fA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 12 LEU A 545
PHE A 123
GLY A 558
LEU A 560
GLU A 456
 None
 1.13A 3tbgC-3w5fA:
undetectable		 3tbgC-3w5fA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 12 LEU A 545
PHE A 123
GLY A 558
LEU A 560
GLU A 456
 None
 1.07A 3tbgD-3w5fA:
undetectable		 3tbgD-3w5fA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 5 ASP A 466
VAL A 543
GLY A 544
ASP A 463
 None
 1.35A 3w9tA-3w5fA:
undetectable		 3w9tA-3w5fA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 5 ASP A 466
VAL A 543
GLY A 544
ASP A 463
 None
 1.34A 3w9tB-3w5fA:
undetectable		 3w9tB-3w5fA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 5 ASP A 466
VAL A 543
GLY A 544
ASP A 463
 None
 1.35A 3w9tC-3w5fA:
undetectable		 3w9tC-3w5fA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 5 ASP A 466
VAL A 543
GLY A 544
ASP A 463
 None
 1.34A 3w9tD-3w5fA:
undetectable		 3w9tD-3w5fA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 5 ASP A 466
VAL A 543
GLY A 544
ASP A 463
 None
 1.35A 3w9tE-3w5fA:
undetectable		 3w9tE-3w5fA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 5 ASP A 466
VAL A 543
GLY A 544
ASP A 463
 None
 1.35A 3w9tF-3w5fA:
undetectable		 3w9tF-3w5fA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 5 ASP A 466
VAL A 543
GLY A 544
ASP A 463
 None
 1.34A 3w9tG-3w5fA:
undetectable		 3w9tG-3w5fA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 11 GLY A 303
PRO A 519
ALA A 496
GLY A 497
ASN A 556
 None
None
EPE  A 805 ( 4.4A)
None
EPE  A 805 (-3.4A)
 1.21A 4a6nA-3w5fA:
undetectable		 4a6nA-3w5fA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 6 ASN A 459
TYR A 470
TYR A 582
LEU A 468
 NAG  A 803 (-2.0A)
None
None
None
 1.25A 4f8yA-3w5fA:
undetectable
4f8yB-3w5fA:
undetectable		 4f8yA-3w5fA:
14.24
4f8yB-3w5fA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 ARG A  50
HIS A  47
TYR A 310
 None
CL  A 807 (-4.3A)
None
 1.30A 4fu8A-3w5fA:
undetectable		 4fu8A-3w5fA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 TYR A 289
GLN A 177
TRP A 248
 EPE  A 804 (-3.9A)
None
None
 1.15A 4kn2C-3w5fA:
undetectable		 4kn2C-3w5fA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 GLU A 250
TYR A 310
GLU A 120
 EPE  A 804 (-3.8A)
None
EPE  A 804 (-3.4A)
 0.75A 4ryaA-3w5fA:
undetectable		 4ryaA-3w5fA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 SER A 542
GLU A 456
ASP A 463
 None
 0.86A 4xudA-3w5fA:
undetectable		 4xudA-3w5fA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 ASP A 378
ARG A 380
TYR A 381
 None
 1.03A 5a7mA-3w5fA:
3.4		 5a7mA-3w5fA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 ASP A 378
ARG A 380
TYR A 381
 None
 1.03A 5a7mB-3w5fA:
2.8		 5a7mB-3w5fA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 7 TYR A 470
GLY A 558
SER A 540
LEU A 500
 None
 1.04A 5bphB-3w5fA:
undetectable		 5bphB-3w5fA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		3 / 3 GLU A  72
TRP A 252
ASN A 180
 CL  A 807 (-4.5A)
EPE  A 804 (-4.0A)
None
 1.04A 5dv4A-3w5fA:
undetectable		 5dv4A-3w5fA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_A_GCSA801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		6 / 12 TYR A  74
CYH A 118
GLU A 120
GLU A 181
GLU A 250
TYR A 289
 CL  A 807 (-4.2A)
EPE  A 804 ( 3.7A)
EPE  A 804 (-3.4A)
EPE  A 804 (-3.3A)
EPE  A 804 (-3.8A)
EPE  A 804 (-3.9A)
 0.61A 5gsmA-3w5fA:
30.4		 5gsmA-3w5fA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_B_GCSB801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		6 / 12 TYR A  74
CYH A 118
GLU A 120
GLU A 181
GLU A 250
TYR A 289
 CL  A 807 (-4.2A)
EPE  A 804 ( 3.7A)
EPE  A 804 (-3.4A)
EPE  A 804 (-3.3A)
EPE  A 804 (-3.8A)
EPE  A 804 (-3.9A)
 0.60A 5gsmB-3w5fA:
20.1		 5gsmB-3w5fA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		5 / 12 ASN A 376
GLN A 358
LEU A 374
LEU A 354
GLU A 359
 None
 1.21A 5nwwA-3w5fA:
undetectable		 5nwwA-3w5fA:
4.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ONL_A_010A302_0
(YNDL)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 5 GLU A 438
GLU A 709
GLU A 589
PHE A 707
 None
 1.30A 5onlA-3w5fA:
undetectable		 5onlA-3w5fA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_A_PA1A206_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 4 TYR A 467
GLY A 544
ASN A 122
ARG A 299
 None
 1.33A 5w7bA-3w5fA:
0.0
5w7bC-3w5fA:
undetectable		 5w7bA-3w5fA:
7.13
5w7bC-3w5fA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 8 TRP A 255
TRP A 252
PHE A 232
HIS A  47
 None
EPE  A 804 (-4.0A)
None
CL  A 807 (-4.3A)
 1.32A 5yj1G-3w5fA:
undetectable
5yj1Y-3w5fA:
undetectable		 5yj1G-3w5fA:
9.37
5yj1Y-3w5fA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 8 HIS A  47
TRP A 255
TRP A 252
PHE A 232
 CL  A 807 (-4.3A)
None
EPE  A 804 (-4.0A)
None
 1.25A 5yj1k-3w5fA:
undetectable
5yj1t-3w5fA:
undetectable		 5yj1k-3w5fA:
9.37
5yj1t-3w5fA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HRJ_A_010A302_0
(YNDL)		 3w5f BETA-GALACTOSIDASE
(Solanum
lycopersicum) 		4 / 5 GLU A 438
GLU A 709
GLU A 589
PHE A 707
 None
 1.30A 6hrjA-3w5fA:
undetectable		 6hrjA-3w5fA:
15.24