SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w5k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3w5k ZINC FINGER PROTEIN
SNAI1
(Homo
sapiens) 		4 / 5 LEU B 250
CYH B 238
ALA B 240
CYH B 241
 None
ZN  B 504 (-2.3A)
ZN  B 504 ( 4.3A)
ZN  B 504 (-2.2A)
 0.92A 1mz9D-3w5kB:
undetectable		 1mz9D-3w5kB:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 3w5k ZINC FINGER PROTEIN
SNAI1
(Homo
sapiens) 		4 / 5 HIS B 212
CYH B 210
HIS B 230
LEU B 227
 None
ZN  B 503 (-2.4A)
ZN  B 503 (-3.2A)
None
 1.25A 3qpkA-3w5kB:
undetectable		 3qpkA-3w5kB:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3w5k ZINC FINGER PROTEIN
SNAI1
(Homo
sapiens) 		3 / 3 TYR B 236
ARG B 247
SER B 246
 None
 1.12A 4dr2I-3w5kB:
undetectable
4dr2J-3w5kB:
undetectable		 4dr2I-3w5kB:
17.95
4dr2J-3w5kB:
16.67