SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w5v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3w5v FERREDOXIN
(Zea
mays) 		4 / 8 GLY A 171
THR A 170
ALA A 169
VAL A 229
 None
 0.86A 2a1hA-3w5vA:
undetectable
2a1hB-3w5vA:
undetectable		 2a1hA-3w5vA:
23.66
2a1hB-3w5vA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 12 LEU A 200
GLY A 173
CYH A 114
ALA A 175
ALA A  98
 None
None
None
FAD  A 401 ( 4.0A)
None
 1.18A 2bm9D-3w5vA:
3.6		 2bm9D-3w5vA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 12 LEU A 200
GLY A 173
CYH A 114
ALA A 175
ALA A  98
 None
None
None
FAD  A 401 ( 4.0A)
None
 1.04A 2br4A-3w5vA:
3.4		 2br4A-3w5vA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 12 LEU A 200
GLY A 173
CYH A 114
ALA A 175
ALA A  98
 None
None
None
FAD  A 401 ( 4.0A)
None
 1.11A 2br4C-3w5vA:
3.3		 2br4C-3w5vA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 12 LEU A 200
GLY A 173
CYH A 114
ALA A 175
ALA A  98
 None
None
None
FAD  A 401 ( 4.0A)
None
 1.13A 2br4D-3w5vA:
3.3		 2br4D-3w5vA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 12 ILE A 174
LEU A 200
GLY A 203
SER A 234
GLN A 237
 None
 1.17A 2e7fB-3w5vA:
undetectable		 2e7fB-3w5vA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 12 ILE A 174
LEU A 200
GLY A 203
SER A 234
GLN A 237
 None
 1.15A 2ogyB-3w5vA:
undetectable		 2ogyB-3w5vA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 9 LEU A 211
ILE A 174
GLY A 173
GLY A 273
SER A 209
 None
 1.15A 2qmmA-3w5vA:
undetectable		 2qmmA-3w5vA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 12 ILE A 174
LEU A 200
GLY A 203
SER A 234
GLN A 237
 None
 1.14A 2ycjA-3w5vA:
undetectable		 2ycjA-3w5vA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 3w5v FERREDOXIN
(Zea
mays) 		4 / 5 TYR A 254
ALA A 240
ALA A 232
TYR A 246
 None
 1.23A 3d91A-3w5vA:
undetectable		 3d91A-3w5vA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 3w5v FERREDOXIN
(Zea
mays) 		4 / 7 ASP A 307
GLN A 308
GLN A  23
GLU A  24
 None
 1.10A 3l2vA-3w5vA:
undetectable		 3l2vA-3w5vA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 9 VAL A  78
VAL A  92
VAL A  39
ILE A 147
GLY A 149
 None
 1.22A 4fwdA-3w5vA:
undetectable		 4fwdA-3w5vA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3w5v FERREDOXIN
(Zea
mays) 		4 / 6 ARG A 178
ARG A 222
GLY A 217
GLU A 221
 None
 1.03A 5cdqA-3w5vA:
undetectable
5cdqC-3w5vA:
undetectable
5cdqD-3w5vA:
undetectable		 5cdqA-3w5vA:
22.43
5cdqC-3w5vA:
22.43
5cdqD-3w5vA:
19.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3w5v FERREDOXIN
(Zea
mays) 		8 / 9 SER A  96
THR A 172
GLY A 173
ALA A 175
CYH A 272
GLY A 273
LEU A 274
GLU A 312
 FAD  A 401 (-3.0A)
FAD  A 401 (-2.9A)
None
FAD  A 401 ( 4.0A)
None
None
None
FAD  A 401 ( 3.9A)
 0.84A 5vw4A-3w5vA:
40.5		 5vw4A-3w5vA:
48.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 8 SER A  96
CYH A 272
GLY A 273
LEU A 274
GLU A 312
 FAD  A 401 (-3.0A)
None
None
None
FAD  A 401 ( 3.9A)
 0.71A 5vw5A-3w5vA:
40.4		 5vw5A-3w5vA:
48.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3w5v FERREDOXIN
(Zea
mays) 		6 / 8 SER A  96
THR A 172
GLY A 173
CYH A 272
GLY A 273
LEU A 274
 FAD  A 401 (-3.0A)
FAD  A 401 (-2.9A)
None
None
None
None
 0.66A 5vw5A-3w5vA:
40.4		 5vw5A-3w5vA:
48.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 3w5v FERREDOXIN
(Zea
mays) 		4 / 6 ILE A  97
TYR A  70
ARG A 178
SER A 179
 None
 1.20A 6f6jA-3w5vA:
undetectable		 6f6jA-3w5vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 12 HIS A 189
ILE A 102
SER A 108
ALA A 101
ASP A 191
 None
 1.15A 6n91A-3w5vA:
undetectable		 6n91A-3w5vA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3w5v FERREDOXIN
(Zea
mays) 		5 / 12 HIS A 189
ILE A 102
SER A 108
ALA A 101
ASP A 191
 None
 1.15A 6n91B-3w5vA:
undetectable		 6n91B-3w5vA:
13.38