SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w64'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 3w64 MAGNETOSOME PROTEIN
MAMM
(Magnetospirillum
gryphiswaldense) 		4 / 6 LEU A 284
VAL A 274
VAL A 217
GLN A 218
 None
 0.95A 1e7aB-3w64A:
undetectable		 1e7aB-3w64A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 3w64 MAGNETOSOME PROTEIN
MAMM
(Magnetospirillum
gryphiswaldense) 		5 / 9 ALA A 248
VAL A 274
ILE A 251
VAL A 222
ILE A 221
 None
 0.94A 1hpvB-3w64A:
undetectable		 1hpvB-3w64A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3w64 MAGNETOSOME PROTEIN
MAMM
(Magnetospirillum
gryphiswaldense) 		4 / 5 ALA A 216
ALA A 239
ALA A 248
VAL A 274
 None
 0.90A 2nyrB-3w64A:
undetectable		 2nyrB-3w64A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 3w64 MAGNETOSOME PROTEIN
MAMM
(Magnetospirillum
gryphiswaldense) 		4 / 8 HIS A 285
SER A 283
ASP A 249
ARG A 240
 None
 1.41A 2rk8A-3w64A:
undetectable		 2rk8A-3w64A:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_B_PPFB3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 3w64 MAGNETOSOME PROTEIN
MAMM
(Magnetospirillum
gryphiswaldense) 		4 / 7 HIS A 285
SER A 283
ASP A 249
ARG A 240
 None
 1.28A 2rk8B-3w64A:
undetectable		 2rk8B-3w64A:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 3w64 MAGNETOSOME PROTEIN
MAMM
(Magnetospirillum
gryphiswaldense) 		5 / 9 ALA A 248
VAL A 274
ILE A 251
VAL A 222
ILE A 221
 None
 1.04A 3ekvB-3w64A:
undetectable		 3ekvB-3w64A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 3w64 MAGNETOSOME PROTEIN
MAMM
(Magnetospirillum
gryphiswaldense) 		5 / 10 ALA A 248
VAL A 274
ILE A 251
VAL A 222
ILE A 221
 None
 1.01A 3nujA-3w64A:
undetectable		 3nujA-3w64A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 3w64 MAGNETOSOME PROTEIN
MAMM
(Magnetospirillum
gryphiswaldense) 		4 / 5 ILE A 221
ALA A 225
HIS A 236
MET A 250
 None
 1.35A 4ac9B-3w64A:
undetectable
4ac9C-3w64A:
undetectable		 4ac9B-3w64A:
12.40
4ac9C-3w64A:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 3w64 MAGNETOSOME PROTEIN
MAMM
(Magnetospirillum
gryphiswaldense) 		5 / 10 ALA A 248
VAL A 274
ILE A 251
VAL A 222
ILE A 221
 None
 0.98A 4dqcA-3w64A:
undetectable		 4dqcA-3w64A:
20.79