SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w6d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 3w6d LYSOZYME-LIKE
CHITINOLYTIC ENZYME
(Ralstonia
sp.
A-471) 		4 / 6 THR A 102
ILE A 207
TYR A 245
THR A 104
 None
 0.94A 3q70A-3w6dA:
undetectable		 3q70A-3w6dA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3w6d LYSOZYME-LIKE
CHITINOLYTIC ENZYME
(Ralstonia
sp.
A-471) 		5 / 7 ILE A 196
GLY A 193
SER A 194
PHE A 130
LEU A 134
 NAG  A 302 ( 4.7A)
None
None
None
None
 1.42A 3v7pA-3w6dA:
undetectable		 3v7pA-3w6dA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 3w6d LYSOZYME-LIKE
CHITINOLYTIC ENZYME
(Ralstonia
sp.
A-471) 		4 / 5 HIS A 179
GLY A 178
TYR A 181
TYR A 177
 None
 1.37A 4ae1B-3w6dA:
undetectable		 4ae1B-3w6dA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FEP_A_SAMA407_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 3w6d LYSOZYME-LIKE
CHITINOLYTIC ENZYME
(Ralstonia
sp.
A-471) 		5 / 12 TYR A 228
GLN A 141
GLY A 157
LEU A 148
TYR A 214
 None
NAG  A 303 (-3.0A)
None
NAG  A 304 ( 4.6A)
NAG  A 302 (-3.7A)
 1.40A 5fepA-3w6dA:
undetectable		 5fepA-3w6dA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FES_A_SAMA408_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 3w6d LYSOZYME-LIKE
CHITINOLYTIC ENZYME
(Ralstonia
sp.
A-471) 		5 / 12 TYR A 228
GLN A 141
GLY A 157
LEU A 148
TYR A 214
 None
NAG  A 303 (-3.0A)
None
NAG  A 304 ( 4.6A)
NAG  A 302 (-3.7A)
 1.35A 5fesA-3w6dA:
undetectable		 5fesA-3w6dA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 3w6d LYSOZYME-LIKE
CHITINOLYTIC ENZYME
(Ralstonia
sp.
A-471) 		5 / 10 TYR A 124
VAL A 202
ILE A 201
LEU A 133
PHE A 130
 None
 0.96A 5hw8C-3w6dA:
undetectable
5hw8H-3w6dA:
undetectable		 5hw8C-3w6dA:
18.82
5hw8H-3w6dA:
18.82