SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w6j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 3w6j SCPA
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A  21
LEU A  24
ILE A  72
HIS A  49
ILE A  48
 None
 1.13A 1tw4B-3w6jA:
undetectable		 1tw4B-3w6jA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 3w6j SCPB
(Geobacillus
stearothermophil
us) 		4 / 5 LEU B 137
ILE B 122
ILE B 110
ALA B 109
 None
 0.77A 2i2zA-3w6jB:
undetectable		 2i2zA-3w6jB:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 3w6j SCPB
(Geobacillus
stearothermophil
us) 		4 / 4 LEU B 137
ILE B 122
ILE B 110
ALA B 109
 None
 0.75A 2i30A-3w6jB:
undetectable		 2i30A-3w6jB:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3w6j SCPB
(Geobacillus
stearothermophil
us) 		5 / 12 LEU B 134
LEU B 137
LEU B 142
ILE B 122
LEU B 170
 None
 1.05A 2pnjA-3w6jB:
undetectable		 2pnjA-3w6jB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3w6j SCPB
(Geobacillus
stearothermophil
us) 		3 / 3 LEU B 134
PRO B 133
LEU B 137
 None
 0.52A 2po7B-3w6jB:
undetectable		 2po7B-3w6jB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3w6j SCPB
(Geobacillus
stearothermophil
us) 		3 / 3 GLY B  96
PRO B  99
LEU B  91
 None
 0.53A 3hcpB-3w6jB:
undetectable		 3hcpB-3w6jB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3w6j SCPB
(Geobacillus
stearothermophil
us) 		3 / 3 LEU B 134
PRO B 133
LEU B 137
 None
 0.53A 3hcrA-3w6jB:
undetectable		 3hcrA-3w6jB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3w6j SCPB
(Geobacillus
stearothermophil
us) 		4 / 4 LEU B  56
LEU B  24
GLN B  68
GLU B  71
 None
 0.68A 4i41A-3w6jB:
undetectable		 4i41A-3w6jB:
20.96