SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 GLU A 447
ILE A 444
ARG A 429
 None
 0.75A 1cd2A-3w6qA:
undetectable		 1cd2A-3w6qA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 7 TYR A 236
GLN A 485
SER A 509
TRP A 351
 None
 1.32A 1eiiA-3w6qA:
undetectable		 1eiiA-3w6qA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 6 PRO A 343
ASP A 497
ASP A 494
TYR A 614
 None
 1.29A 1hpkA-3w6qA:
undetectable		 1hpkA-3w6qA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 ALA A 326
VAL A 331
TRP A 334
 None
 0.88A 1jo3A-3w6qA:
undetectable		 1jo3A-3w6qA:
3.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 ALA A 326
VAL A 331
TRP A 334
 None
 0.88A 1jo3B-3w6qA:
undetectable		 1jo3B-3w6qA:
3.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 10 HIS A 371
HIS A 372
HIS A 332
VAL A 331
LEU A 279
 None
 1.30A 1rj6B-3w6qA:
undetectable		 1rj6B-3w6qA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 372
HIS A 328
HIS A 103
 None
 0.70A 1rjoA-3w6qA:
undetectable		 1rjoA-3w6qA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 6 VAL A 107
THR A 108
LEU A 143
ARG A 142
 None
 1.06A 1s8fB-3w6qA:
undetectable		 1s8fB-3w6qA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 372
HIS A 328
HIS A 103
 None
 0.73A 1w2zA-3w6qA:
undetectable		 1w2zA-3w6qA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 372
HIS A 328
HIS A 103
 None
 0.73A 1w2zC-3w6qA:
undetectable		 1w2zC-3w6qA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 8 TYR A 145
ARG A 153
ALA A 149
LEU A 378
 None
 1.10A 1x8vA-3w6qA:
undetectable		 1x8vA-3w6qA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 8 TYR A  97
PHE A  99
GLU A 296
GLY A 295
 None
 1.01A 1ykiA-3w6qA:
undetectable
1ykiB-3w6qA:
undetectable		 1ykiA-3w6qA:
16.40
1ykiB-3w6qA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 8 TYR A  97
PHE A  99
GLU A 296
GLY A 295
 None
 1.01A 1ykiA-3w6qA:
undetectable
1ykiB-3w6qA:
undetectable		 1ykiA-3w6qA:
16.40
1ykiB-3w6qA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 8 TYR A  97
PHE A  99
GLU A 296
GLY A 295
 None
 1.00A 1ykiC-3w6qA:
undetectable
1ykiD-3w6qA:
undetectable		 1ykiC-3w6qA:
16.40
1ykiD-3w6qA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 8 TYR A  97
PHE A  99
GLU A 296
GLY A 295
 None
 0.96A 1ykiC-3w6qA:
undetectable
1ykiD-3w6qA:
undetectable		 1ykiC-3w6qA:
16.40
1ykiD-3w6qA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 7 TYR A 106
HIS A  67
HIS A 332
TRP A 102
 None
 1.45A 1yvmA-3w6qA:
undetectable		 1yvmA-3w6qA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 372
HIS A 328
HIS A 103
 None
 0.73A 2oqeB-3w6qA:
undetectable		 2oqeB-3w6qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 372
HIS A 328
HIS A 103
 None
 0.72A 2oqeC-3w6qA:
undetectable		 2oqeC-3w6qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 372
HIS A 328
HIS A 103
 None
 0.72A 2oqeF-3w6qA:
undetectable		 2oqeF-3w6qA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 6 VAL A 170
PHE A  42
PRO A 144
TRP A 146
 None
 1.42A 2q6oB-3w6qA:
undetectable		 2q6oB-3w6qA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 7 ILE A 367
GLN A  50
LEU A  46
LEU A 169
 None
 1.03A 2qqcB-3w6qA:
undetectable
2qqcC-3w6qA:
undetectable		 2qqcB-3w6qA:
11.30
2qqcC-3w6qA:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 7 LEU A  46
LEU A 169
ILE A 367
GLN A  50
 None
 1.02A 2qqcA-3w6qA:
undetectable
2qqcF-3w6qA:
undetectable		 2qqcA-3w6qA:
8.94
2qqcF-3w6qA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 7 LEU A  46
LEU A 169
ILE A 367
GLN A  50
 None
 0.99A 2qqcI-3w6qA:
undetectable
2qqcL-3w6qA:
undetectable		 2qqcI-3w6qA:
8.94
2qqcL-3w6qA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 372
HIS A 328
HIS A 103
 None
 0.68A 2w0qA-3w6qA:
undetectable		 2w0qA-3w6qA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 372
HIS A 328
HIS A 103
 None
 0.70A 2w0qB-3w6qA:
undetectable		 2w0qB-3w6qA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 LEU A  27
TYR A  26
GLN A  29
 None
 0.70A 2wekA-3w6qA:
undetectable		 2wekA-3w6qA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A 103
HIS A 328
HIS A 372
HIS A  94
 None
 1.05A 2wkoA-3w6qA:
undetectable		 2wkoA-3w6qA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 5 HIS A 103
HIS A 328
HIS A 372
HIS A  94
 None
 1.04A 2wkoF-3w6qA:
undetectable		 2wkoF-3w6qA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 11 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
 None
 0.70A 2zweA-3w6qA:
18.7
2zweB-3w6qA:
undetectable		 2zweA-3w6qA:
19.06
2zweB-3w6qA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 11 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
 None
 0.73A 2zwfA-3w6qA:
18.7
2zwfB-3w6qA:
undetectable		 2zwfA-3w6qA:
19.06
2zwfB-3w6qA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 11 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
 None
 0.70A 2zwgA-3w6qA:
18.7
2zwgB-3w6qA:
undetectable		 2zwgA-3w6qA:
19.06
2zwgB-3w6qA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A  67
HIS A 372
HIS A 103
 None
 0.70A 3ag4A-3w6qA:
undetectable		 3ag4A-3w6qA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A  67
HIS A 372
HIS A 103
 None
 0.73A 3ag4N-3w6qA:
undetectable		 3ag4N-3w6qA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 LEU A 143
TRP A 428
TYR A 145
 None
 1.00A 3aicH-3w6qA:
undetectable		 3aicH-3w6qA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 SER A 566
GLU A 240
ASP A 224
 None
 0.86A 3bwyA-3w6qA:
undetectable		 3bwyA-3w6qA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 372
HIS A 328
HIS A 103
 None
 0.73A 3hiiA-3w6qA:
undetectable		 3hiiA-3w6qA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 PRO A 265
PHE A 490
ALA A 541
 None
 0.69A 3itaD-3w6qA:
undetectable		 3itaD-3w6qA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A  94
HIS A 103
HIS A  67
 None
 0.47A 3qpkA-3w6qA:
undetectable		 3qpkA-3w6qA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A  94
HIS A 103
HIS A  67
 None
 0.48A 3qpkB-3w6qA:
undetectable		 3qpkB-3w6qA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 10 VAL A 578
ALA A 541
VAL A 507
TYR A 561
ILE A 472
 None
 1.36A 3retA-3w6qA:
undetectable
3retB-3w6qA:
undetectable		 3retA-3w6qA:
8.87
3retB-3w6qA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 6 LEU A 324
PHE A 148
ALA A 149
LEU A 287
 None
 0.96A 3t3zA-3w6qA:
undetectable		 3t3zA-3w6qA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 6 LEU A 324
PHE A 148
ALA A 149
LEU A 287
 None
 0.96A 3t3zB-3w6qA:
undetectable		 3t3zB-3w6qA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 6 LEU A 324
PHE A 148
ALA A 149
LEU A 287
 None
 0.98A 3t3zD-3w6qA:
undetectable		 3t3zD-3w6qA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 5 PRO A 100
ILE A 437
TRP A 428
PHE A 297
 None
 1.19A 3topB-3w6qA:
undetectable		 3topB-3w6qA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 PHE A 227
CYH A 230
HIS A 355
 None
 1.31A 3u9fF-3w6qA:
undetectable		 3u9fF-3w6qA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 6 ARG A 104
HIS A 103
LEU A 324
ASP A 376
 None
 1.23A 4cevA-3w6qA:
undetectable
4cevB-3w6qA:
undetectable		 4cevA-3w6qA:
18.87
4cevB-3w6qA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 6 ASP A 376
ARG A 104
HIS A 103
LEU A 324
 None
 1.21A 4cevA-3w6qA:
undetectable
4cevC-3w6qA:
undetectable		 4cevA-3w6qA:
18.87
4cevC-3w6qA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 6 ARG A 104
HIS A 103
LEU A 324
ASP A 376
 None
 1.21A 4cevD-3w6qA:
undetectable
4cevE-3w6qA:
undetectable		 4cevD-3w6qA:
18.87
4cevE-3w6qA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 6 ARG A 104
HIS A 103
LEU A 324
ASP A 376
 None
 1.22A 4cevE-3w6qA:
undetectable
4cevF-3w6qA:
undetectable		 4cevE-3w6qA:
18.87
4cevF-3w6qA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 8 GLN A 538
ASN A 320
TRP A 321
THR A 300
 None
 1.39A 4d1yA-3w6qA:
undetectable
4d1yB-3w6qA:
undetectable		 4d1yA-3w6qA:
15.09
4d1yB-3w6qA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 6 THR A 233
LEU A  46
ASN A 191
LEU A 169
 None
 1.24A 4nc3A-3w6qA:
undetectable		 4nc3A-3w6qA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		7 / 7 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
VAL A 359
ALA A 362
 None
 0.52A 4p6sA-3w6qA:
19.0		 4p6sA-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 7 HIS A 332
HIS A 372
HIS A  67
ALA A 362
 None
 0.74A 4p6sA-3w6qA:
19.0		 4p6sA-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 7 HIS A  67
HIS A  94
HIS A 328
HIS A 332
VAL A 359
 None
 0.57A 4p6sB-3w6qA:
18.8		 4p6sB-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 7 HIS A  67
HIS A 328
ASN A 329
HIS A 332
VAL A 359
 None
 0.42A 4p6sB-3w6qA:
18.8		 4p6sB-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 PRO A 406
VAL A  93
HIS A  94
 None
 0.75A 4pevC-3w6qA:
undetectable		 4pevC-3w6qA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 7 GLU A  44
THR A  30
LEU A 169
ASN A 191
 None
 1.12A 4pfjA-3w6qA:
undetectable		 4pfjA-3w6qA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 ASP A 467
LYS A 319
LEU A 292
 None
 0.91A 4ptjA-3w6qA:
undetectable		 4ptjA-3w6qA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 MET A 198
GLN A 252
TYR A 194
 None
 1.01A 4udcA-3w6qA:
undetectable		 4udcA-3w6qA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 12 PHE A 148
LEU A 164
LEU A 286
ASP A 147
VAL A 331
 None
 1.20A 4wnwA-3w6qA:
undetectable		 4wnwA-3w6qA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 ASP A 497
LEU A 259
ARG A 256
 None
 0.78A 5e8qA-3w6qA:
undetectable		 5e8qA-3w6qA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		7 / 7 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
VAL A 359
ALA A 362
 None
 0.55A 5i3aA-3w6qA:
18.9		 5i3aA-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 7 HIS A 332
HIS A 372
HIS A  67
ALA A 362
 None
 0.79A 5i3aA-3w6qA:
18.9		 5i3aA-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		7 / 7 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
VAL A 359
ALA A 362
 None
 0.55A 5i3aB-3w6qA:
18.9		 5i3aB-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 7 HIS A 332
HIS A 372
HIS A  67
ALA A 362
 None
 0.81A 5i3aB-3w6qA:
18.9		 5i3aB-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		7 / 7 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
VAL A 359
ALA A 362
 None
 0.53A 5i3bA-3w6qA:
18.3		 5i3bA-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 7 HIS A 332
HIS A 328
HIS A  94
HIS A  67
ALA A 362
 None
 1.27A 5i3bA-3w6qA:
18.3		 5i3bA-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A  67
HIS A  94
HIS A 332
VAL A 359
ALA A 362
 None
 0.40A 5i3bB-3w6qA:
19.0		 5i3bB-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 5 HIS A  67
HIS A 103
HIS A 332
ALA A 362
 None
 1.33A 5i3bB-3w6qA:
19.0		 5i3bB-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 5 HIS A 332
HIS A 328
HIS A  67
ALA A 362
 None
 1.12A 5i3bB-3w6qA:
19.0		 5i3bB-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 5 HIS A 332
HIS A 372
HIS A  67
ALA A 362
 None
 0.83A 5i3bB-3w6qA:
19.0		 5i3bB-3w6qA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 10 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
 None
 0.47A 5m8nA-3w6qA:
10.0		 5m8nA-3w6qA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 10 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
 None
 0.59A 5m8nB-3w6qA:
14.7		 5m8nB-3w6qA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 9 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
 None
 0.54A 5m8nC-3w6qA:
14.6		 5m8nC-3w6qA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 7 HIS A  94
HIS A 328
ASN A 329
HIS A 332
VAL A 359
 None
 0.55A 5m8rA-3w6qA:
14.3		 5m8rA-3w6qA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 8 HIS A  94
HIS A 328
ASN A 329
HIS A 332
VAL A 359
 None
 0.53A 5m8rB-3w6qA:
11.0		 5m8rB-3w6qA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 8 HIS A  94
HIS A 328
ASN A 329
HIS A 332
VAL A 359
 None
 0.56A 5m8rC-3w6qA:
14.5		 5m8rC-3w6qA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 8 HIS A  94
HIS A 328
ASN A 329
HIS A 332
VAL A 359
 None
 0.54A 5m8rD-3w6qA:
14.8		 5m8rD-3w6qA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A 372
HIS A 328
HIS A  67
HIS A 103
HIS A  94
 None
 1.34A 5mejA-3w6qA:
undetectable		 5mejA-3w6qA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A 372
HIS A 328
HIS A  67
HIS A 103
HIS A  94
 None
 1.34A 5mewA-3w6qA:
undetectable		 5mewA-3w6qA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A 372
HIS A 328
HIS A  67
HIS A 103
HIS A  94
 None
 1.34A 5mhuA-3w6qA:
undetectable		 5mhuA-3w6qA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A 372
HIS A 328
HIS A  67
HIS A 103
HIS A  94
 None
 1.34A 5mhvA-3w6qA:
undetectable		 5mhvA-3w6qA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
HIS A 372
HIS A 103
HIS A  67
 None
 0.97A 5mhwA-3w6qA:
undetectable		 5mhwA-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
HIS A 372
HIS A 103
HIS A  67
 None
 0.96A 5mhxA-3w6qA:
undetectable		 5mhxA-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
HIS A 372
HIS A 103
HIS A  67
 None
 0.96A 5mhyA-3w6qA:
undetectable		 5mhyA-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
HIS A 372
HIS A 103
HIS A  67
 None
 0.96A 5mhzA-3w6qA:
undetectable		 5mhzA-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
HIS A 372
HIS A 103
HIS A  67
 None
 0.96A 5mi1A-3w6qA:
undetectable		 5mi1A-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
HIS A 372
HIS A 103
HIS A  67
 None
 0.95A 5mi2A-3w6qA:
undetectable		 5mi2A-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
HIS A 372
HIS A 103
HIS A  67
 None
 0.96A 5miaA-3w6qA:
undetectable		 5miaA-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
HIS A 372
HIS A 103
HIS A  67
 None
 0.95A 5mibA-3w6qA:
undetectable		 5mibA-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
HIS A 372
HIS A 103
HIS A  67
 None
 0.95A 5micA-3w6qA:
undetectable		 5micA-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
HIS A 372
HIS A 103
HIS A  67
 None
 0.95A 5midA-3w6qA:
undetectable		 5midA-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
HIS A 372
HIS A 103
HIS A  67
 None
 0.95A 5mieA-3w6qA:
undetectable		 5mieA-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A  94
HIS A 103
HIS A  67
 None
 0.57A 5migA-3w6qA:
undetectable		 5migA-3w6qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 12 GLN A  50
GLU A  44
LEU A  46
ILE A 114
TYR A   3
 None
 1.45A 5vlmA-3w6qA:
undetectable		 5vlmA-3w6qA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 11 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
 None
 0.75A 5z0hA-3w6qA:
18.5
5z0hB-3w6qA:
undetectable		 5z0hA-3w6qA:
7.46
5z0hB-3w6qA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 11 HIS A  67
HIS A  94
HIS A 328
ASN A 329
HIS A 332
 None
 0.77A 5z0mA-3w6qA:
18.5
5z0mB-3w6qA:
undetectable		 5z0mA-3w6qA:
7.29
5z0mB-3w6qA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  67
CYH A  92
HIS A  94
HIS A 103
 None
 0.85A 5zrdA-3w6qA:
24.1		 5zrdA-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A  94
CYH A  92
HIS A 103
HIS A  67
 None
 1.12A 5zrdA-3w6qA:
24.1		 5zrdA-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 328
HIS A 332
HIS A 372
 None
 0.26A 5zrdA-3w6qA:
24.1		 5zrdA-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A 328
HIS A 332
PHE A 368
HIS A 371
HIS A 372
 None
 0.28A 5zrdB-3w6qA:
24.3		 5zrdB-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A  67
CYH A  92
HIS A  94
HIS A 103
PHE A 368
 None
 0.76A 5zrdB-3w6qA:
24.2		 5zrdB-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A  94
CYH A  92
HIS A 103
HIS A  67
PHE A 513
 None
 1.18A 5zrdB-3w6qA:
24.2		 5zrdB-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 5 HIS A 103
CYH A  92
HIS A  67
HIS A  94
 None
 1.20A 5zrdB-3w6qA:
24.2		 5zrdB-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 5 HIS A 328
HIS A 332
HIS A 372
PHE A  99
 None
 1.04A 5zrdB-3w6qA:
24.2		 5zrdB-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A 328
HIS A 332
HIS A 371
HIS A 372
 None
 0.29A 5zrdC-3w6qA:
23.7		 5zrdC-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A  67
CYH A  92
HIS A  94
HIS A 103
PHE A 368
 None
 0.82A 5zrdC-3w6qA:
23.7		 5zrdC-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A  94
CYH A  92
HIS A 103
HIS A  67
PHE A 513
 None
 1.25A 5zrdC-3w6qA:
23.7		 5zrdC-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 5 HIS A 328
HIS A 332
HIS A 372
PHE A  99
 None
 1.07A 5zrdC-3w6qA:
23.7		 5zrdC-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A  67
CYH A  92
HIS A  94
HIS A 103
PHE A 368
 None
 0.79A 5zrdD-3w6qA:
7.6		 5zrdD-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 5 HIS A  94
CYH A  92
HIS A 103
HIS A  67
PHE A 513
 None
 1.28A 5zrdD-3w6qA:
7.6		 5zrdD-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 5 HIS A 103
CYH A  92
HIS A  67
HIS A  94
 None
 1.21A 5zrdD-3w6qA:
7.6		 5zrdD-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 5 HIS A 328
HIS A 332
HIS A 372
PHE A  99
 None
 1.04A 5zrdD-3w6qA:
7.6		 5zrdD-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 5 HIS A 332
HIS A 372
HIS A 328
PHE A 513
 None
 1.25A 5zrdD-3w6qA:
7.6		 5zrdD-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		4 / 4 HIS A 328
HIS A 332
HIS A 371
HIS A 372
 None
 0.29A 5zrdD-3w6qA:
7.6		 5zrdD-3w6qA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 328
HIS A 372
HIS A 371
 None
 0.70A 6hu9a-3w6qA:
undetectable		 6hu9a-3w6qA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		5 / 11 ASP A 497
SER A 503
GLY A 337
SER A 357
ASN A 487
 None
 1.31A 6hu9A-3w6qA:
undetectable
6hu9E-3w6qA:
undetectable
6hu9I-3w6qA:
undetectable		 6hu9A-3w6qA:
21.41
6hu9E-3w6qA:
14.89
6hu9I-3w6qA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3w6q TYROSINASE
(Aspergillus
oryzae) 		3 / 3 HIS A 328
HIS A 372
HIS A 371
 None
 0.76A 6hu9m-3w6qA:
0.0		 6hu9m-3w6qA:
20.96