SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 3w79 FMN-DEPENDENT
NADH-AZOREDUCTASE
(Bacillus
sp.
B29) 		5 / 10 ILE A   7
PHE A  90
LEU A 166
VAL A 169
LEU A 170
 None
 1.34A 2w98A-3w79A:
undetectable		 2w98A-3w79A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3w79 FMN-DEPENDENT
NADH-AZOREDUCTASE
(Bacillus
sp.
B29) 		3 / 3 GLY A 134
GLY A 171
GLY A 174
 None
 0.39A 3bogC-3w79A:
undetectable		 3bogC-3w79A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3w79 FMN-DEPENDENT
NADH-AZOREDUCTASE
(Bacillus
sp.
B29) 		3 / 3 GLY A 134
GLY A 171
GLY A 174
 None
 0.36A 3bogD-3w79A:
undetectable		 3bogD-3w79A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_1
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 3w79 FMN-DEPENDENT
NADH-AZOREDUCTASE
(Bacillus
sp.
B29) 		5 / 11 VAL A 175
LEU A 170
THR A 168
GLU A 179
ALA A 141
 None
 1.24A 4e0fA-3w79A:
undetectable		 4e0fA-3w79A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_C_EF2C151_1
(CEREBLON ISOFORM 4)		 3w79 FMN-DEPENDENT
NADH-AZOREDUCTASE
(Bacillus
sp.
B29) 		4 / 7 ASN A  12
PRO A  11
PHE A  45
PHE A   6
 None
 1.29A 4v32C-3w79A:
undetectable		 4v32C-3w79A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 3w79 FMN-DEPENDENT
NADH-AZOREDUCTASE
(Bacillus
sp.
B29) 		4 / 8 LEU A 166
VAL A 111
TYR A 180
GLN A 145
 None
 0.99A 5nu7A-3w79A:
undetectable		 5nu7A-3w79A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3w79 FMN-DEPENDENT
NADH-AZOREDUCTASE
(Bacillus
sp.
B29) 		3 / 3 GLU A 179
TYR A 180
ARG A 163
 None
 0.60A 5uunA-3w79A:
undetectable		 5uunA-3w79A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3w79 FMN-DEPENDENT
NADH-AZOREDUCTASE
(Bacillus
sp.
B29) 		3 / 3 GLU A 179
TYR A 180
ARG A 163
 None
 0.66A 5uunB-3w79A:
undetectable		 5uunB-3w79A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3w79 FMN-DEPENDENT
NADH-AZOREDUCTASE
(Bacillus
sp.
B29) 		4 / 6 TYR A 180
ILE A 181
ALA A 146
MET A 102
 None
None
FMN  A 301 (-3.3A)
FMN  A 301 (-3.2A)
 1.04A 6hu9m-3w79A:
undetectable
6hu9q-3w79A:
undetectable		 6hu9m-3w79A:
16.82
6hu9q-3w79A:
18.14