SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		6 / 8 HIS A 836
ASP A 973
SER A 974
SER A 979
GLY A1000
GLY A1010
 None
 0.50A 1aq7A-3w94A:
36.6		 1aq7A-3w94A:
35.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 12 HIS A 836
ASP A 973
SER A 979
GLY A1000
GLY A1010
 None
 0.54A 1etrH-3w94A:
36.1		 1etrH-3w94A:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 8 ASP A 973
SER A 974
SER A 979
GLY A1000
GLY A1010
 None
 0.34A 1f5lA-3w94A:
36.6		 1f5lA-3w94A:
33.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TNL_A_TPAA900_1
(TRYPSIN)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 6 ASP A 973
SER A 974
SER A 979
GLY A1000
GLY A1010
 None
 0.24A 1tnlA-3w94A:
36.9		 1tnlA-3w94A:
35.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		6 / 10 ALA A 834
THR A 833
ALA A 889
ALA A 835
GLY A 995
ALA A1013
 None
 1.31A 2f16K-3w94A:
undetectable
2f16L-3w94A:
undetectable		 2f16K-3w94A:
21.69
2f16L-3w94A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		6 / 10 ALA A 834
THR A 833
ALA A 889
ALA A 835
GLY A 995
ALA A1013
 None
 1.31A 2f16Y-3w94A:
undetectable
2f16Z-3w94A:
undetectable		 2f16Y-3w94A:
21.69
2f16Z-3w94A:
17.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 6 ASP A 973
SER A 974
SER A 979
GLY A1000
GLY A1010
 None
 0.22A 2otvA-3w94A:
37.0		 2otvA-3w94A:
35.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 12 ASP A 973
SER A 979
GLY A1000
GLY A1010
TYR A1012
 None
 0.25A 2p16A-3w94A:
36.3		 2p16A-3w94A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		6 / 8 ASP A 973
SER A 974
GLN A 976
SER A 979
GLY A1000
GLY A1010
 None
 0.53A 2vinA-3w94A:
37.1		 2vinA-3w94A:
33.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		3 / 3 TRP A 902
GLN A 863
TRP A 926
 None
 1.31A 2vqyA-3w94A:
undetectable		 2vqyA-3w94A:
21.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		6 / 12 ASP A 973
SER A 979
GLY A1000
GLY A1002
GLY A1010
TYR A1012
 None
 0.37A 2w26A-3w94A:
36.5		 2w26A-3w94A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		6 / 11 HIS A 836
ASP A 973
SER A 974
SER A 979
GLY A1000
GLY A1010
 None
 0.29A 3gy3A-3w94A:
36.8		 3gy3A-3w94A:
35.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		6 / 12 ALA A 834
THR A 833
ALA A 889
ALA A 835
GLY A 995
ALA A1013
 None
 1.32A 3mg0Y-3w94A:
undetectable
3mg0Z-3w94A:
undetectable		 3mg0Y-3w94A:
21.69
3mg0Z-3w94A:
17.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		4 / 6 SER A 974
SER A 979
GLY A1000
GLY A1010
 None
 0.29A 3rxfA-3w94A:
15.2		 3rxfA-3w94A:
35.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		4 / 5 ASP A 973
SER A 974
SER A 979
GLY A1010
 None
 0.29A 3rxhA-3w94A:
37.2		 3rxhA-3w94A:
35.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 10 LEU A 831
HIS A 813
LEU A 812
ALA A 850
LEU A 852
 None
 1.27A 4p65A-3w94A:
undetectable
4p65B-3w94A:
undetectable
4p65F-3w94A:
undetectable
4p65H-3w94A:
undetectable		 4p65A-3w94A:
4.72
4p65B-3w94A:
9.01
4p65F-3w94A:
9.01
4p65H-3w94A:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 11 LEU A 831
HIS A 813
LEU A 812
ALA A 850
LEU A 852
 None
 1.09A 4p65E-3w94A:
undetectable
4p65F-3w94A:
undetectable
4p65J-3w94A:
undetectable
4p65L-3w94A:
undetectable		 4p65E-3w94A:
4.72
4p65F-3w94A:
9.01
4p65J-3w94A:
9.01
4p65L-3w94A:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 9 ALA A 834
THR A 833
ALA A 835
GLY A 995
ALA A1013
 None
 1.22A 4qvnK-3w94A:
undetectable
4qvnL-3w94A:
undetectable		 4qvnK-3w94A:
21.69
4qvnL-3w94A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 9 ALA A 834
THR A 833
ALA A 835
GLY A 995
ALA A1013
 None
 1.22A 4qvnY-3w94A:
undetectable
4qvnZ-3w94A:
undetectable		 4qvnY-3w94A:
21.69
4qvnZ-3w94A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 11 ALA A1013
ALA A1011
GLY A 981
GLY A 980
ALA A 834
 None
 0.94A 5lf3K-3w94A:
undetectable
5lf3L-3w94A:
undetectable		 5lf3K-3w94A:
22.22
5lf3L-3w94A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 11 ALA A1013
ALA A1011
GLY A 981
GLY A 980
ALA A 834
 None
 0.93A 5lf3Y-3w94A:
undetectable
5lf3Z-3w94A:
undetectable		 5lf3Y-3w94A:
22.22
5lf3Z-3w94A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 12 HIS A 836
ASP A 887
GLY A 977
SER A 979
VAL A1001
 None
 0.88A 6c2mC-3w94A:
10.5		 6c2mC-3w94A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 10 LEU A 946
ASP A 973
LYS A 795
ILE A 994
GLY A 995
 None
 1.28A 6dlzA-3w94A:
undetectable
6dlzD-3w94A:
undetectable		 6dlzA-3w94A:
13.54
6dlzD-3w94A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 10 ILE A 994
GLY A 995
LEU A 946
ASP A 973
LYS A 795
 None
 1.28A 6dlzB-3w94A:
undetectable
6dlzC-3w94A:
undetectable		 6dlzB-3w94A:
13.54
6dlzC-3w94A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 10 LEU A 946
ASP A 973
LYS A 795
ILE A 994
GLY A 995
 None
 1.25A 6dm0B-3w94A:
undetectable
6dm0C-3w94A:
undetectable		 6dm0B-3w94A:
13.54
6dm0C-3w94A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 10 LEU A 946
ASP A 973
LYS A 795
ILE A 994
GLY A 995
 None
 1.28A 6dm1A-3w94A:
undetectable
6dm1D-3w94A:
undetectable		 6dm1A-3w94A:
13.54
6dm1D-3w94A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 10 ILE A 994
GLY A 995
LEU A 946
ASP A 973
LYS A 795
 None
 1.29A 6dm1B-3w94A:
undetectable
6dm1C-3w94A:
undetectable		 6dm1B-3w94A:
13.54
6dm1C-3w94A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		6 / 11 ALA A 834
THR A 833
ALA A 889
ALA A 835
GLY A 995
ALA A1013
 None
 1.31A 6hwdK-3w94A:
undetectable
6hwdL-3w94A:
undetectable		 6hwdK-3w94A:
17.86
6hwdL-3w94A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		6 / 11 ALA A 834
THR A 833
ALA A 889
ALA A 835
GLY A 995
ALA A1013
 None
 1.48A 6hwdK-3w94A:
undetectable
6hwdL-3w94A:
undetectable		 6hwdK-3w94A:
17.86
6hwdL-3w94A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 11 ALA A1013
ALA A1011
GLY A 981
GLY A 980
ALA A 834
 None
 0.90A 6hwdK-3w94A:
undetectable
6hwdL-3w94A:
undetectable		 6hwdK-3w94A:
17.86
6hwdL-3w94A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		6 / 11 ALA A 834
THR A 833
ALA A 889
ALA A 835
GLY A 995
ALA A1013
 None
 1.32A 6hwdY-3w94A:
undetectable
6hwdZ-3w94A:
undetectable		 6hwdY-3w94A:
17.86
6hwdZ-3w94A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		6 / 11 ALA A 834
THR A 833
ALA A 889
ALA A 835
GLY A 995
ALA A1013
 None
 1.48A 6hwdY-3w94A:
undetectable
6hwdZ-3w94A:
undetectable		 6hwdY-3w94A:
17.86
6hwdZ-3w94A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3w94 ENTEROPEPTIDASE-1
(Oryzias
latipes) 		5 / 11 ALA A1013
ALA A1011
GLY A 981
GLY A 980
ALA A 834
 None
 0.90A 6hwdY-3w94A:
undetectable
6hwdZ-3w94A:
undetectable		 6hwdY-3w94A:
17.86
6hwdZ-3w94A:
14.83