SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w95'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3w95 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 6 CYH A 116
VAL A 121
HIS A 118
CYH A  56
 ZN  A 201 (-2.3A)
None
ZN  A 201 (-3.3A)
ZN  A 201 (-2.2A)
 1.48A 1ekjG-3w95A:
undetectable
1ekjH-3w95A:
undetectable		 1ekjG-3w95A:
20.63
1ekjH-3w95A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3w95 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 6 GLN A  95
ASP A  39
VAL A 124
HIS A  21
 None
 1.35A 1ekjG-3w95A:
undetectable
1ekjH-3w95A:
undetectable		 1ekjG-3w95A:
20.63
1ekjH-3w95A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 3w95 GENOME POLYPROTEIN
(Enterovirus
A) 		3 / 4 VAL A  32
TRP A  28
TRP A  33
 None
 1.18A 1gmkA-3w95A:
undetectable
1gmkB-3w95A:
undetectable		 1gmkA-3w95A:
8.21
1gmkB-3w95A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P9G_A_ACTA42_0
(EAFP 2)		 3w95 GENOME POLYPROTEIN
(Enterovirus
A) 		3 / 3 CYH A  58
ARG A 138
CYH A 116
 ZN  A 201 (-2.3A)
None
ZN  A 201 (-2.3A)
 1.18A 1p9gA-3w95A:
undetectable		 1p9gA-3w95A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 3w95 GENOME POLYPROTEIN
(Enterovirus
A) 		5 / 12 GLY A 111
VAL A  84
GLN A  95
SER A  87
ASP A  39
 None
 1.34A 2vqyA-3w95A:
undetectable		 2vqyA-3w95A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 3w95 GENOME POLYPROTEIN
(Enterovirus
A) 		5 / 12 ARG A 115
GLY A   8
GLY A 112
GLN A   6
ALA A   9
 None
 1.32A 3t7sC-3w95A:
undetectable		 3t7sC-3w95A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 3w95 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 8 ILE A  53
GLN A   5
VAL A  17
ASP A 136
 None
 1.09A 5vlmF-3w95A:
undetectable		 5vlmF-3w95A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3w95 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 5 VAL A  84
ARG A  93
PRO A  91
TYR A  90
 None
 1.21A 5x80A-3w95A:
undetectable
5x80B-3w95A:
undetectable		 5x80A-3w95A:
27.42
5x80B-3w95A:
27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3w95 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 5 PRO A  91
TYR A  90
VAL A  84
ARG A  93
 None
 1.23A 5x80C-3w95A:
undetectable
5x80D-3w95A:
undetectable		 5x80C-3w95A:
27.42
5x80D-3w95A:
27.42