SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		5 / 11 VAL A  82
GLU A 231
ILE A 118
VAL A 238
PHE A  27
 None
 1.43A 1gx9A-3w9aA:
undetectable		 1gx9A-3w9aA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		4 / 8 PHE A 177
LEU A 190
TRP A 165
GLY A 156
 None
 0.99A 1rmtC-3w9aA:
undetectable		 1rmtC-3w9aA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		4 / 8 ALA A 125
PHE A 169
THR A 170
LYS A 119
 None
 1.10A 2kotB-3w9aA:
undetectable		 2kotB-3w9aA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		4 / 6 TYR A 179
LEU A 144
VAL A 202
VAL A 203
 None
 1.00A 2z97A-3w9aA:
undetectable		 2z97A-3w9aA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		3 / 3 PRO A 126
GLU A 131
TYR A 146
 None
GOL  A 503 ( 4.4A)
None
 0.69A 2zmbA-3w9aA:
undetectable		 2zmbA-3w9aA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		3 / 3 MET A  94
GLU A  98
ASP A 216
 GOL  A 503 ( 3.9A)
None
None
 1.09A 3a25A-3w9aA:
undetectable		 3a25A-3w9aA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		4 / 7 GLY A 110
PHE A 183
PHE A 217
PHE A 137
 None
 1.02A 3ko0D-3w9aA:
undetectable
3ko0E-3w9aA:
undetectable		 3ko0D-3w9aA:
17.95
3ko0E-3w9aA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		5 / 10 TYR A 179
LEU A 144
GLY A 156
VAL A 202
VAL A 203
 None
 1.12A 3lxiA-3w9aA:
undetectable		 3lxiA-3w9aA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		5 / 12 GLY A  79
LEU A  77
ASN A  28
VAL A 219
GLY A 237
 None
 0.92A 3sglA-3w9aA:
undetectable		 3sglA-3w9aA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		4 / 5 THR A 194
GLY A 196
PRO A 198
ASN A 197
 None
 1.21A 3u8qA-3w9aA:
undetectable		 3u8qA-3w9aA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		4 / 8 TYR A 179
VAL A 219
VAL A  82
ILE A 118
 None
 1.16A 4aftD-3w9aA:
undetectable
4aftE-3w9aA:
undetectable		 4aftD-3w9aA:
21.17
4aftE-3w9aA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		5 / 9 TYR A 179
LEU A 144
GLY A 156
VAL A 202
VAL A 203
 None
 1.09A 4c9kB-3w9aA:
undetectable		 4c9kB-3w9aA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		5 / 10 TYR A 179
LEU A 144
GLY A 156
VAL A 202
VAL A 203
 None
 1.09A 4c9nB-3w9aA:
undetectable		 4c9nB-3w9aA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		5 / 9 TYR A 179
LEU A 144
GLY A 156
VAL A 202
VAL A 203
 None
 1.10A 4c9pA-3w9aA:
undetectable		 4c9pA-3w9aA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		5 / 10 TYR A 179
LEU A 144
GLY A 156
VAL A 202
VAL A 203
 None
 1.08A 4c9pB-3w9aA:
undetectable		 4c9pB-3w9aA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_F_ACTF701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		4 / 4 PHE A 113
HIS A 115
GLY A 243
ILE A 245
 None
 1.02A 4k50E-3w9aA:
undetectable		 4k50E-3w9aA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		5 / 12 GLY A 243
PRO A 244
GLY A  19
ILE A 181
GLY A 110
 None
 1.15A 4n48A-3w9aA:
undetectable		 4n48A-3w9aA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		5 / 12 HIS A 115
ALA A 178
GLU A 241
GLY A 243
GLN A 248
 None
 1.13A 4uilH-3w9aA:
undetectable
4uilL-3w9aA:
undetectable		 4uilH-3w9aA:
19.44
4uilL-3w9aA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		4 / 5 ARG A  20
GLY A  19
GLU A 242
SER A  75
 None
 1.08A 4z3oA-3w9aA:
undetectable
4z3oB-3w9aA:
undetectable		 4z3oA-3w9aA:
17.12
4z3oB-3w9aA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		4 / 5 SER A  75
ARG A  20
GLY A  19
GLU A 242
 None
 1.09A 5cdqA-3w9aA:
undetectable
5cdqB-3w9aA:
undetectable
5cdqC-3w9aA:
undetectable		 5cdqA-3w9aA:
16.94
5cdqB-3w9aA:
22.05
5cdqC-3w9aA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3w9a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Coprinopsis
cinerea) 		4 / 5 SER A  75
ARG A  20
GLY A  19
GLU A 242
 None
 1.07A 5cdqR-3w9aA:
undetectable
5cdqS-3w9aA:
undetectable
5cdqT-3w9aA:
undetectable		 5cdqR-3w9aA:
16.94
5cdqS-3w9aA:
22.05
5cdqT-3w9aA:
16.94