SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 8 LEU A 989
VAL A1007
TYR A 926
GLY A1006
 None
 0.88A 1jlfA-3w9hA:
5.4
1jlfB-3w9hA:
2.6		 1jlfA-3w9hA:
20.17
1jlfB-3w9hA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 989
VAL A1007
TYR A 926
GLY A1006
 None
 0.88A 1lweA-3w9hA:
undetectable		 1lweA-3w9hA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M9J_B_CLWB907_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 5 PRO A 190
VAL A 265
TYR A 779
GLU A 776
 None
 1.21A 1m9jB-3w9hA:
undetectable		 1m9jB-3w9hA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 288
VAL A 612
ALA A 159
LEU A 310
PHE A 628
 None
 1.13A 1nw3A-3w9hA:
undetectable		 1nw3A-3w9hA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 8 PHE A 927
THR A 917
LEU A 555
THR A1013
 None
 1.08A 1o76B-3w9hA:
undetectable		 1o76B-3w9hA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 449
ILE A 445
ALA A 939
ILE A 975
 None
 0.96A 1oniB-3w9hA:
undetectable
1oniC-3w9hA:
undetectable		 1oniB-3w9hA:
10.13
1oniC-3w9hA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 10 GLY A 930
PHE A 927
GLY A1004
THR A 934
VAL A 929
 None
 1.15A 1pwyE-3w9hA:
undetectable		 1pwyE-3w9hA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 THR A 595
ILE A 278
ALA A 627
GLU A 152
PRO A 285
 None
 1.37A 1vq1A-3w9hA:
undetectable		 1vq1A-3w9hA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 SER A 656
VAL A 606
TYR A 598
TYR A 597
VAL A 629
 None
 1.40A 1x70A-3w9hA:
undetectable		 1x70A-3w9hA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 SER A 656
VAL A 606
TYR A 598
TYR A 597
VAL A 629
 None
 1.39A 1x70B-3w9hA:
undetectable		 1x70B-3w9hA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 4 LEU A 376
LEU A 480
SER A 476
LEU A 383
 None
 1.01A 1ya3A-3w9hA:
undetectable		 1ya3A-3w9hA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 5 LEU A 913
PRO A 906
VAL A 909
ILE A 910
 None
 0.96A 2aoiB-3w9hA:
undetectable		 2aoiB-3w9hA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 985
ILE A 349
PRO A 373
VAL A 372
ILE A 402
 None
 0.80A 2avvB-3w9hA:
undetectable		 2avvB-3w9hA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 5 LEU A 289
LEU A 310
ILE A 306
ALA A 165
 None
 0.66A 2i2zA-3w9hA:
undetectable		 2i2zA-3w9hA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 5 LEU A 449
ILE A 445
ILE A 943
ALA A 942
 None
 0.77A 2i2zA-3w9hA:
undetectable		 2i2zA-3w9hA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 8 THR A 330
VAL A 333
VAL A  32
ASN A 391
 None
 1.17A 2ij7C-3w9hA:
undetectable		 2ij7C-3w9hA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 VAL A 986
ALA A 347
PHE A 982
SER A 979
LEU A 937
 None
 1.12A 2oipA-3w9hA:
undetectable		 2oipA-3w9hA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 VAL A 986
ALA A 347
PHE A 982
SER A 979
LEU A 937
 None
 1.08A 2oipC-3w9hA:
undetectable		 2oipC-3w9hA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 6 TYR A 926
TYR A 467
GLN A 469
ILE A 466
 None
 1.11A 2pgzD-3w9hA:
undetectable
2pgzE-3w9hA:
undetectable		 2pgzD-3w9hA:
12.52
2pgzE-3w9hA:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.85A 2pxcA-3w9hA:
undetectable		 2pxcA-3w9hA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 11 GLY A 985
ILE A 349
PRO A 373
VAL A 372
ILE A 402
 None
 0.84A 2r5qB-3w9hA:
undetectable		 2r5qB-3w9hA:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 VAL A 799
GLN A 733
ILE A 746
ASP A 745
PHE A 804
 None
 1.34A 2v95A-3w9hA:
undetectable		 2v95A-3w9hA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 GLY A 930
GLY A 911
GLY A1010
THR A1013
LEU A1017
ILE A 910
 None
 1.48A 2wa2B-3w9hA:
undetectable		 2wa2B-3w9hA:
14.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 ALA A 618
PHE A 666
ARG A 717
ASN A 719
GLY A 720
 None
 1.44A 3aobC-3w9hA:
58.5		 3aobC-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 ALA A 618
PHE A 666
ARG A 717
ASN A 719
LEU A 828
 None
 1.11A 3aobC-3w9hA:
58.5		 3aobC-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 THR A 624
PHE A 666
ARG A 717
ASN A 719
LEU A 828
 None
 0.75A 3aobC-3w9hA:
58.5		 3aobC-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 SER A  79
MET A 575
PHE A 615
ASP A 681
GLU A 683
GLU A 826
 None
 1.17A 3aocC-3w9hA:
57.1		 3aocC-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 SER A  79
SER A 133
ASP A 681
GLU A 683
GLU A 826
 None
 1.02A 3aocC-3w9hA:
57.1		 3aocC-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		9 / 12 SER A  79
SER A 135
MET A 573
PHE A 615
ILE A 626
PHE A 666
ASP A 681
GLU A 683
GLU A 826
 None
 0.48A 3aocC-3w9hA:
57.1		 3aocC-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLN A 577
PHE A 664
ARG A 717
ASN A 719
LEU A 828
 None
 1.13A 3aodC-3w9hA:
56.3		 3aodC-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLN A 577
PHE A 666
ARG A 717
ASN A 719
LEU A 828
 None
 0.85A 3aodC-3w9hA:
56.3		 3aodC-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 MET A 662
ALA A 618
ASN A 719
GLY A 720
LEU A 828
 None
 1.42A 3aodC-3w9hA:
56.3		 3aodC-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 THR A 624
PHE A 664
ARG A 717
ASN A 719
LEU A 828
 None
 1.22A 3aodC-3w9hA:
56.3		 3aodC-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 THR A 624
PHE A 666
ARG A 717
ASN A 719
GLY A 720
LEU A 828
 None
 1.03A 3aodC-3w9hA:
56.3		 3aodC-3w9hA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 GLY A 930
GLY A 911
GLY A1010
THR A1013
LEU A1017
ILE A 910
 None
 1.48A 3elwA-3w9hA:
undetectable		 3elwA-3w9hA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 7 ILE A 277
GLY A 616
VAL A 139
LEU A 591
 None
 0.72A 3elzA-3w9hA:
undetectable		 3elzA-3w9hA:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.93A 3gczA-3w9hA:
undetectable		 3gczA-3w9hA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 VAL A 986
ALA A 347
PHE A 982
SER A 979
LEU A 937
 None
 1.01A 3hj3D-3w9hA:
undetectable		 3hj3D-3w9hA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 ARG A 815
LEU A 721
VAL A 612
ALA A 618
GLY A 619
 None
 0.97A 3ku1A-3w9hA:
undetectable		 3ku1A-3w9hA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 ARG A 815
LEU A 721
VAL A 612
ALA A 618
GLY A 619
 None
 0.93A 3ku1C-3w9hA:
undetectable		 3ku1C-3w9hA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		3 / 3 LEU A 631
TRP A 634
GLY A 996
 None
 0.79A 3l35A-3w9hA:
undetectable
3l35H-3w9hA:
undetectable		 3l35A-3w9hA:
4.44
3l35H-3w9hA:
1.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		3 / 3 LEU A 631
TRP A 634
GLY A 996
 None
 0.80A 3l35B-3w9hA:
1.9
3l35K-3w9hA:
undetectable		 3l35B-3w9hA:
4.44
3l35K-3w9hA:
1.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 9 LEU A 631
VAL A 609
SER A 608
ALA A 651
THR A 648
 None
 1.21A 3mdtA-3w9hA:
undetectable		 3mdtA-3w9hA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A 937
ALA A 981
GLY A 985
GLY A 403
ASP A 407
 None
 1.23A 3ou7D-3w9hA:
undetectable		 3ou7D-3w9hA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.85A 3p97A-3w9hA:
undetectable		 3p97A-3w9hA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.87A 3p97C-3w9hA:
undetectable		 3p97C-3w9hA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 5 LEU A 960
GLY A 959
PHE A1026
ARG A1030
 None
 0.87A 3smtA-3w9hA:
undetectable		 3smtA-3w9hA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 9 ASP A   7
ILE A   6
VAL A 412
THR A 431
GLN A 439
 None
 1.32A 4acaB-3w9hA:
undetectable
4acaC-3w9hA:
undetectable		 4acaB-3w9hA:
19.88
4acaC-3w9hA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.81A 4ctjA-3w9hA:
undetectable		 4ctjA-3w9hA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.83A 4ctkA-3w9hA:
undetectable		 4ctkA-3w9hA:
14.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 GLN A 151
ASP A 276
ILE A 277
ALA A 279
VAL A 612
PHE A 615
 None
 0.82A 4dx5B-3w9hA:
60.6		 4dx5B-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DX7_A_DM2A1105_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 11 GLY A 679
ARG A 717
ASN A 719
GLN A 830
MET A 862
 None
 0.96A 4dx7A-3w9hA:
61.2		 4dx7A-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DX7_A_DM2A1105_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		7 / 11 MET A 575
GLY A 679
ASP A 681
ARG A 717
ASN A 719
GLU A 826
MET A 862
 None
 0.71A 4dx7A-3w9hA:
61.2		 4dx7A-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DX7_A_DM2A1105_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		7 / 11 MET A 575
GLY A 679
ASP A 681
ASN A 719
ARG A 815
GLU A 826
MET A 862
 None
 0.70A 4dx7A-3w9hA:
61.2		 4dx7A-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DX7_A_DM2A1105_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		7 / 11 MET A 575
THR A 676
ASP A 681
ASN A 719
ARG A 815
GLU A 826
MET A 862
 None
 0.95A 4dx7A-3w9hA:
61.2		 4dx7A-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 11 SER A 134
MET A 575
PHE A 666
ASN A 667
ARG A 717
 None
 0.98A 4dx7A-3w9hA:
61.2		 4dx7A-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 8 SER A  46
GLN A  89
GLU A 130
ILE A 277
VAL A 612
 None
 0.90A 4dx7B-3w9hA:
57.1		 4dx7B-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 8 SER A  46
GLN A  89
GLU A 130
PHE A 178
 None
 0.82A 4dx7B-3w9hA:
57.1		 4dx7B-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 8 SER A  46
GLN A  89
ILE A 277
VAL A 612
PHE A 615
 None
 0.94A 4dx7B-3w9hA:
57.1		 4dx7B-3w9hA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 7 PHE A 801
ASN A 194
THR A 749
ILE A 746
PHE A 804
 None
 1.47A 4ejjA-3w9hA:
undetectable		 4ejjA-3w9hA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 8 LEU A 944
ILE A 945
ARG A 971
ILE A 975
 None
 0.71A 4em2A-3w9hA:
1.4		 4em2A-3w9hA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 10 ILE A 370
ALA A 371
THR A 489
VAL A 412
MET A 977
 None
 1.48A 4kq8A-3w9hA:
undetectable		 4kq8A-3w9hA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 ALA A 916
GLY A1010
GLY A 911
GLY A 930
LEU A 400
 None
 1.21A 4n48B-3w9hA:
undetectable		 4n48B-3w9hA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A 376
PHE A 380
ILE A 402
GLY A 397
VAL A 340
 None
 1.10A 4nkvA-3w9hA:
undetectable		 4nkvA-3w9hA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A 376
PHE A 380
ILE A 402
GLY A 397
VAL A 340
 None
 1.06A 4nkvC-3w9hA:
undetectable		 4nkvC-3w9hA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A 376
PHE A 380
ILE A 402
GLY A 397
VAL A 340
 None
 1.07A 4nkvD-3w9hA:
undetectable		 4nkvD-3w9hA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A 376
PHE A 380
ILE A 402
GLY A 397
VAL A 340
 None
 1.04A 4nkxA-3w9hA:
2.2		 4nkxA-3w9hA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		3 / 3 PRO A 565
LEU A 564
GLN A  34
 None
 0.64A 4pevB-3w9hA:
undetectable		 4pevB-3w9hA:
20.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 ASN A 274
ASP A 276
ALA A 279
PHE A 610
VAL A 612
PHE A 615
 None
 0.89A 4u8vB-3w9hA:
40.6		 4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		7 / 12 GLN A 151
ASP A 276
ILE A 277
ALA A 279
PHE A 610
VAL A 612
PHE A 615
 None
 0.78A 4u8vB-3w9hA:
40.6		 4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLN A 151
SER A 180
ALA A 279
PHE A 610
VAL A 612
 None
 1.02A 4u8vB-3w9hA:
40.6		 4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 179
ALA A 279
PHE A 610
VAL A 612
PHE A 615
 None
 0.93A 4u8vB-3w9hA:
40.6		 4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 179
SER A 180
ALA A 279
PHE A 610
VAL A 612
 None
 0.97A 4u8vB-3w9hA:
40.6		 4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 SER A 180
ASN A 274
ALA A 279
PHE A 610
VAL A 612
 None
 1.04A 4u8vB-3w9hA:
40.6		 4u8vB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		7 / 12 GLU A 273
ASP A 276
ILE A 277
ALA A 279
PHE A 610
VAL A 612
PHE A 615
 None
 0.85A 4u8yB-3w9hA:
59.0		 4u8yB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 GLY A 179
GLU A 273
ALA A 279
PHE A 610
VAL A 612
PHE A 615
 None
 1.21A 4u8yB-3w9hA:
59.0		 4u8yB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 GLY A 179
SER A 180
GLU A 273
ALA A 279
PHE A 610
VAL A 612
 None
 1.18A 4u8yB-3w9hA:
59.0		 4u8yB-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 GLU A 273
ASP A 276
ILE A 277
ALA A 279
VAL A 612
ARG A 620
 None
 1.22A 4u95B-3w9hA:
60.4		 4u95B-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 GLU A 273
ASP A 276
ILE A 277
ALA A 279
VAL A 612
PHE A 615
 None
 0.78A 4u95B-3w9hA:
60.4		 4u95B-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 SER A  48
GLU A 273
ASP A 276
ILE A 277
VAL A 612
PHE A 615
 None
 0.92A 4u95B-3w9hA:
60.4		 4u95B-3w9hA:
99.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 SER A  48
PHE A 178
GLY A 179
SER A 180
GLU A 273
 None
 0.93A 4u95B-3w9hA:
60.4		 4u95B-3w9hA:
99.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 11 GLY A 290
LEU A 289
PHE A 610
ALA A 279
SER A 287
 None
 1.26A 4wnuC-3w9hA:
1.6		 4wnuC-3w9hA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A 405
ALA A 347
VAL A 351
ALA A 981
ILE A 348
 None
 1.17A 4x1kD-3w9hA:
undetectable		 4x1kD-3w9hA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		3 / 5 GLY A 957
GLY A 959
GLU A 962
 None
 0.45A 4z2eA-3w9hA:
2.5
4z2eD-3w9hA:
undetectable		 4z2eA-3w9hA:
20.42
4z2eD-3w9hA:
13.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 SER A  79
MET A 573
GLU A 673
GLU A 683
LEU A 828
THR A 860
 None
 1.10A 4zjlA-3w9hA:
59.1		 4zjlA-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		8 / 12 SER A  79
MET A 575
PHE A 615
GLU A 683
LEU A 828
THR A 860
GLY A 861
MET A 862
 None
 1.13A 4zjlA-3w9hA:
59.1		 4zjlA-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 SER A  79
SER A 133
GLU A 683
THR A 860
GLY A 861
MET A 862
 None
 1.03A 4zjlA-3w9hA:
59.1		 4zjlA-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		9 / 12 SER A  79
SER A 135
MET A 573
PHE A 615
GLU A 683
LEU A 828
THR A 860
GLY A 861
MET A 862
 None
 0.86A 4zjlA-3w9hA:
59.1		 4zjlA-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJL_A_ERYA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 5 ASN A  81
SER A 134
LYS A 292
ASP A 681
GLU A 826
 None
 0.79A 4zjlA-3w9hA:
59.1		 4zjlA-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJL_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 SER A  79
ASN A  81
PHE A 615
PHE A 617
GLU A 826
 None
 1.09A 4zjlD-3w9hA:
59.1		 4zjlD-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJL_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 SER A  79
ASN A  81
SER A 133
ASP A 681
GLU A 826
MET A 862
 None
 1.33A 4zjlD-3w9hA:
59.1		 4zjlD-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJL_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		8 / 12 SER A  79
ASN A  81
SER A 135
PHE A 615
ASN A 719
GLU A 817
GLU A 826
MET A 862
 None
 0.92A 4zjlD-3w9hA:
59.1		 4zjlD-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJL_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		8 / 12 SER A  79
ASN A  81
SER A 135
PHE A 615
ASP A 681
ASN A 719
GLU A 826
MET A 862
 None
 0.92A 4zjlD-3w9hA:
59.1		 4zjlD-3w9hA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJO_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 ALA A 618
ASP A 681
GLU A 826
LEU A 828
MET A 862
 None
 1.01A 4zjoA-3w9hA:
59.9		 4zjoA-3w9hA:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJO_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 SER A  79
ASN A  81
GLU A 683
GLU A 817
LEU A 828
THR A 860
 None
 0.87A 4zjoA-3w9hA:
59.9		 4zjoA-3w9hA:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJO_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		8 / 12 SER A  79
ASN A  81
SER A 133
ASP A 681
GLU A 683
GLU A 826
THR A 860
MET A 862
 None
 1.33A 4zjoA-3w9hA:
59.9		 4zjoA-3w9hA:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJO_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		9 / 12 SER A  79
ASN A  81
SER A 135
ASP A 681
GLU A 683
GLU A 826
LEU A 828
THR A 860
MET A 862
 None
 0.96A 4zjoA-3w9hA:
59.9		 4zjoA-3w9hA:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJO_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		9 / 12 SER A  79
ASN A  81
SER A 135
MET A 573
ASP A 681
GLU A 826
LEU A 828
THR A 860
MET A 862
 None
 0.95A 4zjoA-3w9hA:
59.9		 4zjoA-3w9hA:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 11 SER A 134
LYS A 292
ALA A 618
ASP A 681
GLU A 826
 None
 1.25A 4zjoD-3w9hA:
59.0		 4zjoD-3w9hA:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 11 THR A  93
SER A 134
ALA A 618
ASP A 681
GLU A 826
 None
 1.42A 4zjoD-3w9hA:
59.0		 4zjoD-3w9hA:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		8 / 11 TYR A  77
SER A  79
THR A  91
LYS A 292
ASP A 681
GLU A 826
THR A 860
GLY A 861
 None
 0.72A 4zjoD-3w9hA:
59.0		 4zjoD-3w9hA:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		8 / 11 TYR A  77
THR A  91
SER A 134
LYS A 292
ASP A 681
GLU A 826
THR A 860
GLY A 861
 None
 0.77A 4zjoD-3w9hA:
59.0		 4zjoD-3w9hA:
99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJQ_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		9 / 11 SER A  79
LYS A 292
MET A 573
LEU A 668
ASP A 681
ASN A 719
GLU A 826
GLY A 861
MET A 862
 None
 0.86A 4zjqA-3w9hA:
58.7		 4zjqA-3w9hA:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJQ_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		9 / 11 SER A  79
SER A 134
LYS A 292
MET A 573
LEU A 668
ASP A 681
ASN A 719
GLU A 826
GLY A 861
 None
 0.97A 4zjqA-3w9hA:
58.7		 4zjqA-3w9hA:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 ASN A  81
SER A 134
MET A 573
PHE A 666
ARG A 815
GLU A 817
 None
 1.12A 4zjqD-3w9hA:
58.3		 4zjqD-3w9hA:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 SER A  79
ASN A  81
THR A  91
PHE A 664
ARG A 815
 None
 1.28A 4zjqD-3w9hA:
58.3		 4zjqD-3w9hA:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		6 / 12 SER A  79
ASN A  81
THR A  91
PHE A 664
ASP A 681
GLU A 826
 None
 0.92A 4zjqD-3w9hA:
58.3		 4zjqD-3w9hA:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		8 / 12 SER A  79
ASN A  81
THR A  91
SER A 134
LYS A 292
MET A 573
ILE A 626
ARG A 815
 None
 1.09A 4zjqD-3w9hA:
58.3		 4zjqD-3w9hA:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		9 / 12 SER A  79
ASN A  81
THR A  91
SER A 134
LYS A 292
MET A 573
ILE A 626
ASP A 681
GLU A 826
 None
 0.96A 4zjqD-3w9hA:
58.3		 4zjqD-3w9hA:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		8 / 12 SER A  79
ASN A  81
THR A  91
SER A 134
LYS A 292
MET A 573
PHE A 666
ARG A 815
 None
 1.15A 4zjqD-3w9hA:
58.3		 4zjqD-3w9hA:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		9 / 12 SER A  79
ASN A  81
THR A  91
SER A 134
LYS A 292
MET A 573
PHE A 666
ASP A 681
GLU A 826
 None
 0.94A 4zjqD-3w9hA:
58.3		 4zjqD-3w9hA:
99.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.83A 5e9qA-3w9hA:
undetectable		 5e9qA-3w9hA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.88A 5e9qC-3w9hA:
undetectable		 5e9qC-3w9hA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.83A 5ec8C-3w9hA:
undetectable		 5ec8C-3w9hA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.82A 5ehgA-3w9hA:
undetectable		 5ehgA-3w9hA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.82A 5ehiA-3w9hA:
undetectable		 5ehiA-3w9hA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.86A 5ehiC-3w9hA:
undetectable		 5ehiC-3w9hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.82A 5eifA-3w9hA:
undetectable		 5eifA-3w9hA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.87A 5eifC-3w9hA:
undetectable		 5eifC-3w9hA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.83A 5eiwA-3w9hA:
undetectable		 5eiwA-3w9hA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.83A 5ekxA-3w9hA:
undetectable		 5ekxA-3w9hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A 404
GLY A 985
PRO A 988
LEU A 989
LEU A 400
 None
 1.03A 5emlA-3w9hA:
undetectable		 5emlA-3w9hA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 MET A1011
THR A1015
LEU A1017
ALA A1018
GLY A 936
 None
 1.04A 5gs4A-3w9hA:
undetectable		 5gs4A-3w9hA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 8 GLN A 577
ASP A  83
GLY A 616
ASN A 623
 None
 0.88A 5hwaA-3w9hA:
1.6		 5hwaA-3w9hA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.81A 5ikmA-3w9hA:
undetectable		 5ikmA-3w9hA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 ALA A 654
PHE A 178
ILE A 277
PHE A 628
THR A 648
 None
 1.25A 5jlcA-3w9hA:
undetectable		 5jlcA-3w9hA:
19.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 5 LEU A 300
LYS A 334
HIS A 338
VAL A 341
 None
 0.96A 5jmnB-3w9hA:
60.0		 5jmnB-3w9hA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		3 / 3 VAL A 340
ARG A 468
PRO A  36
 None
 0.81A 5koxA-3w9hA:
2.5		 5koxA-3w9hA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.84A 5kqrA-3w9hA:
undetectable		 5kqrA-3w9hA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.84A 5kqsA-3w9hA:
undetectable		 5kqsA-3w9hA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.87A 5m5bA-3w9hA:
undetectable		 5m5bA-3w9hA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.85A 5njvA-3w9hA:
undetectable		 5njvA-3w9hA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.84A 5njvB-3w9hA:
undetectable		 5njvB-3w9hA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		4 / 7 GLN A1000
GLY A 994
ILE A 335
ASP A 633
 None
 1.11A 5vlmC-3w9hA:
undetectable		 5vlmC-3w9hA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 ALA A 999
GLY A 998
SER A 997
LEU A 989
PHE A 396
 None
 1.20A 5w7pA-3w9hA:
undetectable		 5w7pA-3w9hA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.87A 5wz1B-3w9hA:
undetectable		 5wz1B-3w9hA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.84A 5wz2A-3w9hA:
undetectable		 5wz2A-3w9hA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3w9h ACRIFLAVINE
RESISTANCE PROTEIN B
(Escherichia
coli) 		5 / 12 GLY A 290
GLY A 288
GLY A 179
ASP A 328
ILE A 291
 None
 0.83A 5wz2B-3w9hA:
undetectable		 5wz2B-3w9hA:
12.67