SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w9r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 3w9r ABSCISIC ACID
RECEPTOR PYL9
(Arabidopsis
thaliana) 		5 / 12 THR A  17
VAL A 128
LEU A 173
TYR A 122
VAL A  53
 None
None
None
A8S  A 201 (-4.4A)
None
 1.29A 3frqA-3w9rA:
undetectable		 3frqA-3w9rA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3w9r ABSCISIC ACID
RECEPTOR PYL9
(Arabidopsis
thaliana) 		3 / 3 TYR A 160
LEU A 126
ARG A 167
 None
 0.71A 3sufB-3w9rA:
undetectable		 3sufB-3w9rA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3w9r ABSCISIC ACID
RECEPTOR PYL9
(Arabidopsis
thaliana) 		4 / 4 VAL A 146
LEU A  28
ASN A 121
ASP A 148
 None
 1.33A 5vcyA-3w9rA:
undetectable		 5vcyA-3w9rA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 3w9r ABSCISIC ACID
RECEPTOR PYL9
(Arabidopsis
thaliana) 		4 / 8 GLY A  73
ARG A  55
VAL A  71
ASP A  57
 None
 0.96A 5vlmA-3w9rA:
undetectable		 5vlmA-3w9rA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3w9r ABSCISIC ACID
RECEPTOR PYL9
(Arabidopsis
thaliana) 		3 / 3 GLY A 115
THR A  93
GLU A  82
 None
 0.52A 6b58A-3w9rA:
undetectable		 6b58A-3w9rA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 3w9r ABSCISIC ACID
RECEPTOR PYL9
(Arabidopsis
thaliana) 		4 / 5 THR A 127
THR A  35
HIS A  25
GLY A  14
 None
 1.16A 6gbnC-3w9rA:
undetectable		 6gbnC-3w9rA:
19.35