SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w9s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 3w9s OMPR FAMILY RESPONSE
REGULATOR IN
TWO-COMPONENT
REGULATORY SYSTEM
WITH BASS
(Klebsiella
pneumoniae) 		3 / 3 ASP A   8
LEU A  52
LEU A  54
 MG  A 202 (-2.6A)
BEF  A 201 (-4.5A)
None
 0.69A 1ikeA-3w9sA:
undetectable		 1ikeA-3w9sA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 3w9s OMPR FAMILY RESPONSE
REGULATOR IN
TWO-COMPONENT
REGULATORY SYSTEM
WITH BASS
(Klebsiella
pneumoniae) 		3 / 3 ASP A   8
LEU A  52
LEU A  54
 MG  A 202 (-2.6A)
BEF  A 201 (-4.5A)
None
 0.75A 1np1B-3w9sA:
undetectable		 1np1B-3w9sA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3w9s OMPR FAMILY RESPONSE
REGULATOR IN
TWO-COMPONENT
REGULATORY SYSTEM
WITH BASS
(Klebsiella
pneumoniae) 		5 / 12 TYR A  98
GLY A  90
THR A  79
SER A  64
ASP A  86
 None
None
BEF  A 201 (-3.7A)
None
None
 1.11A 1nt2A-3w9sA:
3.6		 1nt2A-3w9sA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 3w9s OMPR FAMILY RESPONSE
REGULATOR IN
TWO-COMPONENT
REGULATORY SYSTEM
WITH BASS
(Klebsiella
pneumoniae) 		5 / 10 LEU A 108
LEU A  76
SER A  46
LEU A  47
LYS A   2
 None
 1.25A 2ceoB-3w9sA:
undetectable		 2ceoB-3w9sA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 3w9s OMPR FAMILY RESPONSE
REGULATOR IN
TWO-COMPONENT
REGULATORY SYSTEM
WITH BASS
(Klebsiella
pneumoniae) 		4 / 6 ALA A  37
PHE A  62
ILE A   6
VAL A  30
 None
 0.89A 2cizA-3w9sA:
undetectable		 2cizA-3w9sA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 3w9s OMPR FAMILY RESPONSE
REGULATOR IN
TWO-COMPONENT
REGULATORY SYSTEM
WITH BASS
(Klebsiella
pneumoniae) 		4 / 8 GLY A  94
ALA A  95
ASP A  96
THR A  79
 None
None
None
BEF  A 201 (-3.7A)
 0.60A 3el0A-3w9sA:
undetectable		 3el0A-3w9sA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3w9s OMPR FAMILY RESPONSE
REGULATOR IN
TWO-COMPONENT
REGULATORY SYSTEM
WITH BASS
(Klebsiella
pneumoniae) 		4 / 8 ASP A   8
ASP A   9
ASP A  58
ASP A  86
 MG  A 202 (-2.6A)
None
None
None
 1.08A 3havA-3w9sA:
undetectable		 3havA-3w9sA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 3w9s OMPR FAMILY RESPONSE
REGULATOR IN
TWO-COMPONENT
REGULATORY SYSTEM
WITH BASS
(Klebsiella
pneumoniae) 		4 / 5 LEU A 108
LEU A  12
THR A  79
PRO A  55
 None
None
BEF  A 201 (-3.7A)
None
 1.01A 6ew0F-3w9sA:
undetectable		 6ew0F-3w9sA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 3w9s OMPR FAMILY RESPONSE
REGULATOR IN
TWO-COMPONENT
REGULATORY SYSTEM
WITH BASS
(Klebsiella
pneumoniae) 		4 / 6 LEU A 108
LEU A  12
THR A  79
PRO A  55
 None
None
BEF  A 201 (-3.7A)
None
 1.01A 6ew0G-3w9sA:
undetectable		 6ew0G-3w9sA:
19.08