SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		4 / 6 ALA A  90
TRP A 273
LEU A 342
TRP A 346
 None
 1.17A 1gahA-3w9vA:
undetectable		 1gahA-3w9vA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 11 GLU A 142
GLY A  31
GLU A  68
LEU A  40
GLU A  41
 None
PO4  A 401 (-3.5A)
None
None
None
 1.33A 1mjqA-3w9vA:
undetectable
1mjqB-3w9vA:
undetectable		 1mjqA-3w9vA:
13.00
1mjqB-3w9vA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 12 GLY A  31
GLU A  68
LEU A  40
GLU A  41
ALA A  38
 PO4  A 401 (-3.5A)
None
None
None
None
 1.12A 1mjqC-3w9vA:
undetectable
1mjqD-3w9vA:
undetectable		 1mjqC-3w9vA:
13.00
1mjqD-3w9vA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 12 GLY A  31
GLU A  68
LEU A  40
GLU A  41
ALA A  38
 PO4  A 401 (-3.5A)
None
None
None
None
 1.12A 1mjqI-3w9vA:
undetectable
1mjqJ-3w9vA:
undetectable		 1mjqI-3w9vA:
13.00
1mjqJ-3w9vA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		4 / 4 SER A  88
VAL A 350
PHE A 319
VAL A  19
 None
 1.44A 1o86A-3w9vA:
undetectable		 1o86A-3w9vA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 11 ARG A 140
GLY A  33
GLU A 142
SER A  60
ILE A  37
 PO4  A 401 (-2.9A)
None
None
None
None
 1.45A 1odiE-3w9vA:
undetectable		 1odiE-3w9vA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 11 ARG A 140
GLY A  33
GLU A 142
SER A  60
ILE A  37
 PO4  A 401 (-2.9A)
None
None
None
None
 1.49A 1odiF-3w9vA:
undetectable		 1odiF-3w9vA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		3 / 3 ASP A 224
GLU A 243
ARG A 131
 None
 0.86A 1wopA-3w9vA:
undetectable		 1wopA-3w9vA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		4 / 7 ASP A 318
THR A  21
ILE A   2
PHE A 303
 None
 1.20A 2jc9A-3w9vA:
undetectable		 2jc9A-3w9vA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		4 / 8 TYR A 307
ARG A 374
THR A 313
GLN A 312
 None
 1.44A 2vxaF-3w9vA:
undetectable
2vxaG-3w9vA:
undetectable
2vxaI-3w9vA:
undetectable		 2vxaF-3w9vA:
12.54
2vxaG-3w9vA:
12.54
2vxaI-3w9vA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 10 GLU A 161
VAL A 186
ALA A 187
PHE A 171
PHE A 150
 GOL  A 402 ( 4.6A)
None
None
None
None
 1.37A 3a3yA-3w9vA:
undetectable		 3a3yA-3w9vA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 12 GLY A 101
GLY A 130
VAL A 115
PHE A 116
ILE A 208
 None
 0.92A 3eluA-3w9vA:
undetectable		 3eluA-3w9vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		3 / 3 SER A 144
GLY A 145
THR A 146
 PO4  A 401 (-2.7A)
PO4  A 401 (-3.6A)
PO4  A 401 (-3.6A)
 0.09A 3k9wA-3w9vA:
undetectable		 3k9wA-3w9vA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 12 VAL A  89
ALA A  90
GLY A 297
ALA A 248
LEU A  13
 None
 1.19A 3qxyA-3w9vA:
undetectable		 3qxyA-3w9vA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 11 VAL A  89
ALA A  90
GLY A 297
ALA A 248
LEU A  13
 None
 1.19A 3rc0A-3w9vA:
undetectable		 3rc0A-3w9vA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 12 VAL A  89
ALA A  90
GLY A 297
ALA A 248
LEU A  13
 None
 1.20A 3rc0B-3w9vA:
undetectable		 3rc0B-3w9vA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		3 / 3 ASP A 224
VAL A 105
ASN A 251
 None
 0.68A 4lmnA-3w9vA:
undetectable		 4lmnA-3w9vA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		4 / 7 VAL A 115
ILE A 208
ILE A  95
ALA A 230
 None
 0.79A 4lv9A-3w9vA:
undetectable		 4lv9A-3w9vA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 12 GLY A 325
TYR A  14
LEU A  20
TYR A  27
THR A 321
 None
 1.03A 5eskA-3w9vA:
undetectable		 5eskA-3w9vA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		4 / 6 TYR A 307
HIS A  56
ILE A 302
TYR A  72
 None
 1.22A 5ih0A-3w9vA:
undetectable		 5ih0A-3w9vA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		4 / 6 VAL A 368
LEU A  83
SER A 304
ILE A 302
 None
 0.98A 5jw1A-3w9vA:
undetectable		 5jw1A-3w9vA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		4 / 5 GLU A  68
GLY A  33
SER A  62
GLY A 145
 None
None
None
PO4  A 401 (-3.6A)
 1.06A 5kprA-3w9vA:
undetectable		 5kprA-3w9vA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_A_ACTA301_0
(ANTIBODY FAB HEAVY
CHAIN)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		4 / 4 THR A  91
VAL A  89
PRO A  10
THR A 299
 None
 1.37A 5mthA-3w9vA:
undetectable
5mthH-3w9vA:
undetectable		 5mthA-3w9vA:
19.06
5mthH-3w9vA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		4 / 7 THR A 180
LEU A 182
VAL A 138
TYR A 139
 None
 1.07A 5ov9A-3w9vA:
undetectable		 5ov9A-3w9vA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 12 PHE A 116
PHE A 150
VAL A 194
GLN A 136
VAL A 115
 None
 1.22A 5tudD-3w9vA:
undetectable		 5tudD-3w9vA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_B_ADNB401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 3w9v PHOSPHATE-BINDING
PROTEIN
(unidentified
prokaryotic
organism) 		5 / 12 GLY A 118
ILE A 135
ASP A 122
LEU A 182
ALA A 183
 None
 1.06A 6bq4B-3w9vA:
undetectable		 6bq4B-3w9vA:
11.97