SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3w9y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3w9y DISKS LARGE HOMOLOG
1
(Homo
sapiens) 		5 / 12 THR A 768
GLY A 812
GLU A 802
GLY A 804
VAL A 765
 None
 1.24A 1n2xA-3w9yA:
undetectable		 1n2xA-3w9yA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3w9y DISKS LARGE HOMOLOG
1
(Homo
sapiens) 		4 / 6 PHE A 800
HIS A 783
THR A 768
VAL A 785
 None
 1.19A 3lb3A-3w9yA:
undetectable		 3lb3A-3w9yA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3w9y DISKS LARGE HOMOLOG
1
(Homo
sapiens) 		4 / 6 PHE A 800
HIS A 783
THR A 768
VAL A 785
 None
 1.26A 3lb3B-3w9yA:
undetectable		 3lb3B-3w9yA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 3w9y DISKS LARGE HOMOLOG
1
(Homo
sapiens) 		3 / 3 ASP A 794
GLU A 789
SER A 817
 None
 0.79A 3p2kA-3w9yA:
undetectable		 3p2kA-3w9yA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 3w9y DISKS LARGE HOMOLOG
1
(Homo
sapiens) 		4 / 7 ARG A 773
TYR A 811
GLU A 776
ASP A 781
 None
 1.08A 4zz8A-3w9yA:
undetectable		 4zz8A-3w9yA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3w9y DISKS LARGE HOMOLOG
1
(Homo
sapiens) 		5 / 10 ILE A 909
ILE A 848
VAL A 906
ASN A 750
ILE A 741
 None
 1.24A 5lg3F-3w9yA:
undetectable		 5lg3F-3w9yA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3w9y DISKS LARGE HOMOLOG
1
(Homo
sapiens) 		5 / 10 ILE A 909
ILE A 848
VAL A 906
ASN A 750
ILE A 741
 None
 1.25A 5lg3G-3w9yA:
undetectable		 5lg3G-3w9yA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3w9y DISKS LARGE HOMOLOG
1
(Homo
sapiens) 		5 / 10 ILE A 909
ILE A 848
VAL A 906
ASN A 750
ILE A 741
 None
 1.23A 5lg3H-3w9yA:
undetectable		 5lg3H-3w9yA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_B_PFLB410_1
(PROTON-GATED ION
CHANNEL)		 3w9y DISKS LARGE HOMOLOG
1
(Homo
sapiens) 		5 / 9 ILE A 909
ILE A 910
VAL A 894
TYR A 903
ILE A 749
 None
 1.12A 5mvnB-3w9yA:
undetectable		 5mvnB-3w9yA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 3w9y DISKS LARGE HOMOLOG
1
(Homo
sapiens) 		5 / 10 ILE A 909
ILE A 910
VAL A 894
TYR A 903
ILE A 749
 None
 1.13A 5mvnD-3w9yA:
undetectable		 5mvnD-3w9yA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3w9y DISKS LARGE HOMOLOG
1
(Homo
sapiens) 		4 / 7 ILE A 902
GLN A 905
VAL A 906
ILE A 741
 None
 0.80A 6cduF-3w9yA:
undetectable
6cduG-3w9yA:
undetectable		 6cduF-3w9yA:
20.92
6cduG-3w9yA:
20.92