SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wa1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 LEU A 164
ALA A 190
LEU A 188
SER A 159
 None
 1.03A 1ictB-3wa1A:
undetectable		 1ictB-3wa1A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		5 / 12 VAL A 157
LEU A 188
SER A 184
PHE A 177
THR A 173
 None
 1.13A 1kw0A-3wa1A:
undetectable		 1kw0A-3wa1A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		5 / 11 VAL A 157
LEU A 188
SER A 184
PHE A 177
THR A 173
 None
 1.17A 1mmtA-3wa1A:
undetectable		 1mmtA-3wa1A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		5 / 12 ASN A 352
HIS A 280
ASN A 354
ILE A 400
LEU A 219
 None
 1.15A 1r30B-3wa1A:
undetectable		 1r30B-3wa1A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 5 TYR A 360
SER A 394
THR A 401
ASN A 354
 None
 1.20A 1yvpA-3wa1A:
undetectable		 1yvpA-3wa1A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 TYR A 360
SER A 394
THR A 401
ASN A 354
 None
 1.17A 1yvpB-3wa1A:
undetectable		 1yvpB-3wa1A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		3 / 3 ASP A  77
TYR A  76
LYS A  45
 None
 1.17A 2othA-3wa1A:
undetectable		 2othA-3wa1A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		3 / 3 LEU A 204
PRO A 205
LEU A  30
 None
 0.49A 2qd5B-3wa1A:
undetectable		 2qd5B-3wa1A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 5 PRO A 109
ILE A 120
ARG A 122
ASP A 106
 None
 1.48A 2rhmB-3wa1A:
undetectable		 2rhmB-3wa1A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 LEU A 164
ALA A 190
LEU A 188
SER A 159
 None
 0.90A 3cfqA-3wa1A:
undetectable		 3cfqA-3wa1A:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		5 / 12 ILE A  96
ALA A  97
ASN A 193
ILE A  37
LEU A  44
 None
 1.12A 3dzuA-3wa1A:
undetectable		 3dzuA-3wa1A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 3hsnA-3wa1A:
undetectable
3hsnB-3wa1A:
undetectable		 3hsnA-3wa1A:
22.22
3hsnB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 3hsoA-3wa1A:
undetectable
3hsoB-3wa1A:
undetectable		 3hsoA-3wa1A:
22.22
3hsoB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 3jt4A-3wa1A:
undetectable
3jt4B-3wa1A:
undetectable		 3jt4A-3wa1A:
22.22
3jt4B-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.50A 3jt4A-3wa1A:
undetectable
3jt4B-3wa1A:
undetectable		 3jt4A-3wa1A:
22.22
3jt4B-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 3jt5A-3wa1A:
undetectable
3jt5B-3wa1A:
undetectable		 3jt5A-3wa1A:
22.22
3jt5B-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.49A 3jtaA-3wa1A:
undetectable
3jtaB-3wa1A:
undetectable		 3jtaA-3wa1A:
22.22
3jtaB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.49A 3jwtA-3wa1A:
undetectable
3jwtB-3wa1A:
undetectable		 3jwtA-3wa1A:
22.22
3jwtB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.48A 3jwuA-3wa1A:
undetectable
3jwuB-3wa1A:
undetectable		 3jwuA-3wa1A:
22.22
3jwuB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.46A 3jwvA-3wa1A:
undetectable
3jwvB-3wa1A:
undetectable		 3jwvA-3wa1A:
22.22
3jwvB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.50A 3jwvA-3wa1A:
undetectable
3jwvB-3wa1A:
undetectable		 3jwvA-3wa1A:
22.22
3jwvB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 3jx0A-3wa1A:
undetectable
3jx0B-3wa1A:
undetectable		 3jx0A-3wa1A:
22.22
3jx0B-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 3n2rA-3wa1A:
undetectable
3n2rB-3wa1A:
undetectable		 3n2rA-3wa1A:
22.22
3n2rB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.45A 3n5vA-3wa1A:
undetectable
3n5vB-3wa1A:
undetectable		 3n5vA-3wa1A:
22.22
3n5vB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.48A 3n5vA-3wa1A:
undetectable
3n5vB-3wa1A:
undetectable		 3n5vA-3wa1A:
22.22
3n5vB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.44A 3n5yA-3wa1A:
undetectable
3n5yB-3wa1A:
undetectable		 3n5yA-3wa1A:
22.22
3n5yB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.48A 3n5yA-3wa1A:
undetectable
3n5yB-3wa1A:
undetectable		 3n5yA-3wa1A:
22.22
3n5yB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.45A 3n5zA-3wa1A:
undetectable
3n5zB-3wa1A:
undetectable		 3n5zA-3wa1A:
22.22
3n5zB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.49A 3n5zA-3wa1A:
undetectable
3n5zB-3wa1A:
undetectable		 3n5zA-3wa1A:
22.22
3n5zB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 3nlvA-3wa1A:
undetectable
3nlvB-3wa1A:
undetectable		 3nlvA-3wa1A:
22.22
3nlvB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.49A 3nlxA-3wa1A:
undetectable
3nlxB-3wa1A:
undetectable		 3nlxA-3wa1A:
22.22
3nlxB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.47A 3nlyA-3wa1A:
undetectable
3nlyB-3wa1A:
undetectable		 3nlyA-3wa1A:
22.22
3nlyB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.47A 3pnfA-3wa1A:
undetectable
3pnfB-3wa1A:
undetectable		 3pnfA-3wa1A:
22.22
3pnfB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.50A 3q99A-3wa1A:
undetectable
3q99B-3wa1A:
undetectable		 3q99A-3wa1A:
22.22
3q99B-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 3tylA-3wa1A:
undetectable
3tylB-3wa1A:
undetectable		 3tylA-3wa1A:
22.22
3tylB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 3tymA-3wa1A:
undetectable
3tymB-3wa1A:
undetectable		 3tymA-3wa1A:
22.22
3tymB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.48A 3ufoA-3wa1A:
undetectable
3ufoB-3wa1A:
undetectable		 3ufoA-3wa1A:
22.22
3ufoB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 3ufsA-3wa1A:
undetectable
3ufsB-3wa1A:
undetectable		 3ufsA-3wa1A:
22.22
3ufsB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 3ufvA-3wa1A:
undetectable
3ufvB-3wa1A:
undetectable		 3ufvA-3wa1A:
22.22
3ufvB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		3 / 3 LEU A 204
PRO A 205
LEU A  30
 None
 0.35A 3w1wB-3wa1A:
undetectable		 3w1wB-3wa1A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 4c39A-3wa1A:
undetectable
4c39B-3wa1A:
undetectable		 4c39A-3wa1A:
22.22
4c39B-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 4capA-3wa1A:
undetectable
4capB-3wa1A:
undetectable		 4capA-3wa1A:
22.22
4capB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.46A 4ctrA-3wa1A:
undetectable
4ctrB-3wa1A:
undetectable		 4ctrA-3wa1A:
22.22
4ctrB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.48A 4cttA-3wa1A:
undetectable
4cttB-3wa1A:
undetectable		 4cttA-3wa1A:
22.22
4cttB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.50A 4ctwA-3wa1A:
undetectable
4ctwB-3wa1A:
undetectable		 4ctwA-3wa1A:
22.22
4ctwB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 4cx6A-3wa1A:
undetectable
4cx6B-3wa1A:
undetectable		 4cx6A-3wa1A:
22.22
4cx6B-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.47A 4d32A-3wa1A:
undetectable
4d32B-3wa1A:
undetectable		 4d32A-3wa1A:
22.22
4d32B-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		3 / 3 ASP A 100
ARG A  99
ASP A  80
 None
 0.72A 4fp9A-3wa1A:
undetectable		 4fp9A-3wa1A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		3 / 3 ASP A 100
ARG A  99
ASP A  80
 None
 0.73A 4fp9C-3wa1A:
undetectable		 4fp9C-3wa1A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		3 / 3 ASP A 100
ARG A  99
ASP A  80
 None
 0.64A 4fp9F-3wa1A:
undetectable		 4fp9F-3wa1A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.47A 4fvzA-3wa1A:
undetectable
4fvzB-3wa1A:
undetectable		 4fvzA-3wa1A:
22.22
4fvzB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.43A 4jsfA-3wa1A:
undetectable
4jsfB-3wa1A:
undetectable		 4jsfA-3wa1A:
22.22
4jsfB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.48A 4jsgA-3wa1A:
undetectable
4jsgB-3wa1A:
undetectable		 4jsgA-3wa1A:
21.47
4jsgB-3wa1A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.49A 4jsgA-3wa1A:
undetectable
4jsgB-3wa1A:
undetectable		 4jsgA-3wa1A:
21.47
4jsgB-3wa1A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.48A 4jsiA-3wa1A:
undetectable
4jsiB-3wa1A:
undetectable		 4jsiA-3wa1A:
22.22
4jsiB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 4jsjA-3wa1A:
undetectable
4jsjB-3wa1A:
undetectable		 4jsjA-3wa1A:
22.22
4jsjB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		3 / 3 VAL A 374
GLY A 376
LYS A 372
 None
 0.70A 4k50E-3wa1A:
undetectable		 4k50E-3wa1A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 4k5dA-3wa1A:
undetectable
4k5dB-3wa1A:
undetectable		 4k5dA-3wa1A:
22.22
4k5dB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 4kciA-3wa1A:
undetectable
4kciB-3wa1A:
undetectable		 4kciA-3wa1A:
22.22
4kciB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 4kcjA-3wa1A:
undetectable
4kcjB-3wa1A:
undetectable		 4kcjA-3wa1A:
22.22
4kcjB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 4kcnA-3wa1A:
undetectable
4kcnB-3wa1A:
undetectable		 4kcnA-3wa1A:
22.22
4kcnB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 4 LYS A  57
ASN A 160
ASP A 165
ASP A  80
 None
 1.34A 4o1eB-3wa1A:
undetectable		 4o1eB-3wa1A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ILE A 242
GLY A 102
ILE A  74
ILE A  85
 None
 0.74A 4o8fB-3wa1A:
undetectable		 4o8fB-3wa1A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		5 / 12 LEU A 170
GLN A 134
ILE A 119
ILE A  96
PHE A 132
 None
 1.00A 4rp8C-3wa1A:
undetectable		 4rp8C-3wa1A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 4uh5A-3wa1A:
undetectable
4uh5B-3wa1A:
undetectable		 4uh5A-3wa1A:
21.93
4uh5B-3wa1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.50A 4upoA-3wa1A:
undetectable
4upoB-3wa1A:
undetectable		 4upoA-3wa1A:
22.22
4upoB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 4uppA-3wa1A:
undetectable
4uppB-3wa1A:
undetectable		 4uppA-3wa1A:
22.22
4uppB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 4v3vA-3wa1A:
undetectable
4v3vB-3wa1A:
undetectable		 4v3vA-3wa1A:
22.22
4v3vB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.42A 4v3wA-3wa1A:
undetectable
4v3wB-3wa1A:
undetectable		 4v3wA-3wa1A:
22.22
4v3wB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 4v3yA-3wa1A:
undetectable
4v3yB-3wa1A:
undetectable		 4v3yA-3wa1A:
22.22
4v3yB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.44A 5ad4A-3wa1A:
undetectable
5ad4B-3wa1A:
undetectable		 5ad4A-3wa1A:
22.22
5ad4B-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.49A 5ad4A-3wa1A:
undetectable
5ad4B-3wa1A:
undetectable		 5ad4A-3wa1A:
22.22
5ad4B-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.45A 5fvpA-3wa1A:
undetectable
5fvpB-3wa1A:
undetectable		 5fvpA-3wa1A:
22.22
5fvpB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 5fvrA-3wa1A:
undetectable
5fvrB-3wa1A:
undetectable		 5fvrA-3wa1A:
22.22
5fvrB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 5fvsA-3wa1A:
undetectable
5fvsB-3wa1A:
undetectable		 5fvsA-3wa1A:
22.22
5fvsB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 5fvtA-3wa1A:
undetectable
5fvtB-3wa1A:
undetectable		 5fvtA-3wa1A:
22.22
5fvtB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.46A 5fvwA-3wa1A:
undetectable
5fvwB-3wa1A:
undetectable		 5fvwA-3wa1A:
21.93
5fvwB-3wa1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.49A 5fvwA-3wa1A:
undetectable
5fvwB-3wa1A:
undetectable		 5fvwA-3wa1A:
21.93
5fvwB-3wa1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 5fvxA-3wa1A:
undetectable
5fvxB-3wa1A:
undetectable		 5fvxA-3wa1A:
21.93
5fvxB-3wa1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 5fw0A-3wa1A:
undetectable
5fw0B-3wa1A:
undetectable		 5fw0A-3wa1A:
22.22
5fw0B-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.48A 5untA-3wa1A:
undetectable
5untB-3wa1A:
undetectable		 5untA-3wa1A:
22.22
5untB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.40A 5unvA-3wa1A:
undetectable
5unvB-3wa1A:
undetectable		 5unvA-3wa1A:
22.22
5unvB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.43A 5unvA-3wa1A:
undetectable
5unvB-3wa1A:
undetectable		 5unvA-3wa1A:
22.22
5unvB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.38A 5vujA-3wa1A:
undetectable
5vujB-3wa1A:
undetectable		 5vujA-3wa1A:
22.22
5vujB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE A 311
GLU A 267
ARG A 388
VAL A 385
 None
 1.45A 5vujA-3wa1A:
undetectable
5vujB-3wa1A:
undetectable		 5vujA-3wa1A:
22.22
5vujB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 5vukA-3wa1A:
undetectable
5vukB-3wa1A:
undetectable		 5vukA-3wa1A:
22.22
5vukB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.48A 5vumA-3wa1A:
undetectable
5vumB-3wa1A:
undetectable		 5vumA-3wa1A:
22.22
5vumB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 5vunA-3wa1A:
undetectable
5vunB-3wa1A:
undetectable		 5vunA-3wa1A:
22.22
5vunB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 5vuoA-3wa1A:
undetectable
5vuoB-3wa1A:
undetectable		 5vuoA-3wa1A:
22.22
5vuoB-3wa1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.49A 5vuwA-3wa1A:
undetectable
5vuwB-3wa1A:
undetectable		 5vuwA-3wa1A:
21.93
5vuwB-3wa1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ALA A 309
GLY A 342
GLY A 290
THR A 337
 None
 0.80A 5ybbB-3wa1A:
undetectable		 5ybbB-3wa1A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.46A 6auqA-3wa1A:
undetectable
6auqB-3wa1A:
undetectable		 6auqA-3wa1A:
12.61
6auqB-3wa1A:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 6auwA-3wa1A:
undetectable
6auwB-3wa1A:
undetectable		 6auwA-3wa1A:
12.61
6auwB-3wa1A:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 6auzA-3wa1A:
undetectable
6auzB-3wa1A:
undetectable		 6auzA-3wa1A:
13.86
6auzB-3wa1A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG A 388
VAL A 385
PHE A 311
GLU A 267
 None
 1.50A 6av1A-3wa1A:
undetectable
6av1B-3wa1A:
undetectable		 6av1A-3wa1A:
13.86
6av1B-3wa1A:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		5 / 11 ASP A 106
PHE A 105
LEU A  84
LEU A 158
ARG A  82
 None
 1.47A 6fgcA-3wa1A:
undetectable		 6fgcA-3wa1A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 5 TYR A 150
VAL A 104
PHE A 146
GLY A 136
 None
 1.40A 6hd4A-3wa1A:
undetectable		 6hd4A-3wa1A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3wa1 BINB PROTEIN
(Lysinibacillus
sphaericus) 		4 / 8 TYR A 265
ALA A 366
VAL A 385
ARG A 367
 None
 1.04A 6hu9a-3wa1A:
undetectable
6hu9e-3wa1A:
undetectable		 6hu9a-3wa1A:
20.79
6hu9e-3wa1A:
14.85