SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wa5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3wa5 TSE3-SPECIFIC
IMMUNITY PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 GLY B  41
PHE B  42
PRO B  39
ASP B  23
 None
 1.10A 2aouB-3wa5B:
undetectable		 2aouB-3wa5B:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3wa5 TSE3-SPECIFIC
IMMUNITY PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 PHE B  42
PHE B  24
ALA B 137
ALA B 133
THR B 131
 None
 1.34A 2x2nA-3wa5B:
undetectable		 2x2nA-3wa5B:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3wa5 TSE3-SPECIFIC
IMMUNITY PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 PHE B  42
PHE B  24
ALA B 137
ALA B 133
THR B 131
 None
 1.27A 2x2nB-3wa5B:
undetectable		 2x2nB-3wa5B:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3wa5 TSE3-SPECIFIC
IMMUNITY PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 PHE B  42
PHE B  24
ALA B 137
ALA B 133
THR B 131
 None
 1.28A 2x2nC-3wa5B:
undetectable		 2x2nC-3wa5B:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3wa5 TSE3-SPECIFIC
IMMUNITY PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 PHE B  42
PHE B  24
ALA B 137
ALA B 133
THR B 131
 None
 1.36A 2x2nD-3wa5B:
undetectable		 2x2nD-3wa5B:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3wa5 TSE3-SPECIFIC
IMMUNITY PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL B  36
ARG B  89
PRO B 111
 None
 0.86A 5koxA-3wa5B:
undetectable		 5koxA-3wa5B:
16.14