SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wa8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_A_DVAA8_0 (GRAMICIDIN A)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	3 / 3	VAL A 73 TRP A 69 TRP A 159	None	1.33A	1c4dA-3wa8A: undetectable 1c4dB-3wa8A: undetectable	1c4dA-3wa8A: 7.38 1c4dB-3wa8A: 7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_J_CHDJ3060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.74A	1v54A-3wa8A: undetectable 1v54J-3wa8A: undetectable	1v54A-3wa8A: 13.36 1v54J-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_W_CHDW4060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.81A	1v54N-3wa8A: undetectable 1v54W-3wa8A: undetectable	1v54N-3wa8A: 13.36 1v54W-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V55_J_CHDJ3060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.77A	1v55A-3wa8A: undetectable 1v55J-3wa8A: undetectable	1v55A-3wa8A: 13.36 1v55J-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.73A	2dyrA-3wa8A: undetectable 2dyrJ-3wa8A: undetectable	2dyrA-3wa8A: 13.36 2dyrJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.77A	2dyrN-3wa8A: undetectable 2dyrW-3wa8A: undetectable	2dyrN-3wa8A: 13.36 2dyrW-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_J_CHDJ101_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.70A	2dysA-3wa8A: undetectable 2dysJ-3wa8A: undetectable	2dysA-3wa8A: 13.36 2dysJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_W_CHDW101_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.80A	2dysN-3wa8A: undetectable 2dysW-3wa8A: undetectable	2dysN-3wa8A: 13.36 2dysW-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIJ_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.77A	2eijA-3wa8A: undetectable 2eijJ-3wa8A: undetectable	2eijA-3wa8A: 13.36 2eijJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIJ_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 8	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.81A	2eijN-3wa8A: undetectable 2eijW-3wa8A: undetectable	2eijN-3wa8A: 13.36 2eijW-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.74A	2eikA-3wa8A: undetectable 2eikJ-3wa8A: undetectable	2eikA-3wa8A: 13.36 2eikJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 8	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.81A	2eikN-3wa8A: undetectable 2eikW-3wa8A: undetectable	2eikN-3wa8A: 13.36 2eikW-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.74A	2eilA-3wa8A: undetectable 2eilJ-3wa8A: undetectable	2eilA-3wa8A: 13.36 2eilJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 8	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.79A	2eilN-3wa8A: undetectable 2eilW-3wa8A: undetectable	2eilN-3wa8A: 13.36 2eilW-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZXW_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.73A	2zxwA-3wa8A: undetectable 2zxwJ-3wa8A: undetectable	2zxwA-3wa8A: 13.36 2zxwJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABL_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.71A	3ablA-3wa8A: undetectable 3ablJ-3wa8A: undetectable	3ablA-3wa8A: 13.36 3ablJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABL_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 8	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.75A	3ablN-3wa8A: undetectable 3ablW-3wa8A: undetectable	3ablN-3wa8A: 13.36 3ablW-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABM_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.71A	3abmA-3wa8A: undetectable 3abmJ-3wa8A: undetectable	3abmA-3wa8A: 13.36 3abmJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG3_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.76A	3ag3A-3wa8A: undetectable 3ag3J-3wa8A: undetectable	3ag3A-3wa8A: 13.36 3ag3J-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG3_W_CHDW1059_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 8	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.68A	3ag3N-3wa8A: undetectable 3ag3W-3wa8A: undetectable	3ag3N-3wa8A: 13.36 3ag3W-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_J_CHDJ60_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.68A	3asnA-3wa8A: undetectable 3asnJ-3wa8A: undetectable	3asnA-3wa8A: 13.36 3asnJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_W_CHDW1059_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 8	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.81A	3asnN-3wa8A: undetectable 3asnW-3wa8A: undetectable	3asnN-3wa8A: 13.36 3asnW-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_J_CHDJ60_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.70A	3asoA-3wa8A: undetectable 3asoJ-3wa8A: undetectable	3asoA-3wa8A: 13.36 3asoJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WEO_A_ACRA1001_2 (ALPHA-GLUCOSIDASE)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	ILE A 128 ILE A 157 MET A 145 TRP A 180	None	1.08A	3weoA-3wa8A: undetectable	3weoA-3wa8A: 12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KR3_A_GLYA701_0 (GLYCINE--TRNA LIGASE)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	ARG A 13 ARG A 104 GLU A 161 SER A 160	None None None HG A 302 ( 4.2A)	1.29A	4kr3A-3wa8A: undetectable	4kr3A-3wa8A: 15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	1.01A	5b1bA-3wa8A: undetectable 5b1bJ-3wa8A: undetectable	5b1bA-3wa8A: 13.36 5b1bJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IY5_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.82A	5iy5A-3wa8A: undetectable 5iy5J-3wa8A: undetectable	5iy5A-3wa8A: 13.36 5iy5J-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0S_B_SAMB501_0 (PEPTIDE N-METHYLTRANSFERASE)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	5 / 12	ILE A 155 SER A 74 GLN A 147 ILE A 110 ALA A 109	None	1.16A	5n0sB-3wa8A: undetectable	5n0sB-3wa8A: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OY0_2_PQN2843_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	5 / 12	ILE A 194 PHE A 184 ILE A 149 ALA A 109 ALA A 183	None	1.13A	5oy02-3wa8A: undetectable	5oy02-3wa8A: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1F_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 6	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.86A	5x1fA-3wa8A: undetectable 5x1fJ-3wa8A: undetectable	5x1fA-3wa8A: 13.36 5x1fJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDQ_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.93A	5xdqN-3wa8A: undetectable 5xdqW-3wa8A: undetectable	5xdqN-3wa8A: 13.36 5xdqW-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDX_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.84A	5xdxA-3wa8A: undetectable 5xdxJ-3wa8A: undetectable	5xdxA-3wa8A: 13.36 5xdxJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDX_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 8	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.93A	5xdxN-3wa8A: undetectable 5xdxW-3wa8A: undetectable	5xdxN-3wa8A: 13.36 5xdxW-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B0C_D_TA1D502_1 (TUBULIN BETA CHAIN)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	5 / 12	LEU A 138 LEU A 166 LEU A 142 GLY A 30 LEU A 31	None HG A 301 ( 3.9A) None None None	0.88A	6b0cD-3wa8A: undetectable	6b0cD-3wa8A: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMF_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.82A	6nmfA-3wa8A: undetectable 6nmfJ-3wa8A: undetectable	6nmfA-3wa8A: 13.36 6nmfJ-3wa8A: 15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3wa8	CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY (Meiothermus ruber)	4 / 7	LEU A 68 ARG A 164 THR A 105 LEU A 106	None	0.87A	6nmpA-3wa8A: undetectable 6nmpJ-3wa8A: undetectable	6nmpA-3wa8A: 13.36 6nmpJ-3wa8A: 15.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C4D_A_DVAA8_0","GRAMICIDIN A","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",3,"VAL A  73;TRP A  69;TRP A 159","None","1.33A","1c4dA-3wa8A:undetectable;1c4dB-3wa8A:undetectable","1c4dA-3wa8A:7.38;1c4dB-3wa8A:7.38"],["1V54_J_CHDJ3060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.74A","1v54A-3wa8A:undetectable;1v54J-3wa8A:undetectable","1v54A-3wa8A:13.36;1v54J-3wa8A:15.74"],["1V54_W_CHDW4060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.81A","1v54N-3wa8A:undetectable;1v54W-3wa8A:undetectable","1v54N-3wa8A:13.36;1v54W-3wa8A:15.74"],["1V55_J_CHDJ3060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.77A","1v55A-3wa8A:undetectable;1v55J-3wa8A:undetectable","1v55A-3wa8A:13.36;1v55J-3wa8A:15.74"],["2DYR_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.73A","2dyrA-3wa8A:undetectable;2dyrJ-3wa8A:undetectable","2dyrA-3wa8A:13.36;2dyrJ-3wa8A:15.74"],["2DYR_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.77A","2dyrN-3wa8A:undetectable;2dyrW-3wa8A:undetectable","2dyrN-3wa8A:13.36;2dyrW-3wa8A:15.74"],["2DYS_J_CHDJ101_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.70A","2dysA-3wa8A:undetectable;2dysJ-3wa8A:undetectable","2dysA-3wa8A:13.36;2dysJ-3wa8A:15.74"],["2DYS_W_CHDW101_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.80A","2dysN-3wa8A:undetectable;2dysW-3wa8A:undetectable","2dysN-3wa8A:13.36;2dysW-3wa8A:15.74"],["2EIJ_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.77A","2eijA-3wa8A:undetectable;2eijJ-3wa8A:undetectable","2eijA-3wa8A:13.36;2eijJ-3wa8A:15.74"],["2EIJ_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.81A","2eijN-3wa8A:undetectable;2eijW-3wa8A:undetectable","2eijN-3wa8A:13.36;2eijW-3wa8A:15.74"],["2EIK_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.74A","2eikA-3wa8A:undetectable;2eikJ-3wa8A:undetectable","2eikA-3wa8A:13.36;2eikJ-3wa8A:15.74"],["2EIK_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.81A","2eikN-3wa8A:undetectable;2eikW-3wa8A:undetectable","2eikN-3wa8A:13.36;2eikW-3wa8A:15.74"],["2EIL_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.74A","2eilA-3wa8A:undetectable;2eilJ-3wa8A:undetectable","2eilA-3wa8A:13.36;2eilJ-3wa8A:15.74"],["2EIL_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.79A","2eilN-3wa8A:undetectable;2eilW-3wa8A:undetectable","2eilN-3wa8A:13.36;2eilW-3wa8A:15.74"],["2ZXW_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.73A","2zxwA-3wa8A:undetectable;2zxwJ-3wa8A:undetectable","2zxwA-3wa8A:13.36;2zxwJ-3wa8A:15.74"],["3ABL_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.71A","3ablA-3wa8A:undetectable;3ablJ-3wa8A:undetectable","3ablA-3wa8A:13.36;3ablJ-3wa8A:15.74"],["3ABL_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.75A","3ablN-3wa8A:undetectable;3ablW-3wa8A:undetectable","3ablN-3wa8A:13.36;3ablW-3wa8A:15.74"],["3ABM_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.71A","3abmA-3wa8A:undetectable;3abmJ-3wa8A:undetectable","3abmA-3wa8A:13.36;3abmJ-3wa8A:15.74"],["3AG3_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.76A","3ag3A-3wa8A:undetectable;3ag3J-3wa8A:undetectable","3ag3A-3wa8A:13.36;3ag3J-3wa8A:15.74"],["3AG3_W_CHDW1059_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.68A","3ag3N-3wa8A:undetectable;3ag3W-3wa8A:undetectable","3ag3N-3wa8A:13.36;3ag3W-3wa8A:15.74"],["3ASN_J_CHDJ60_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.68A","3asnA-3wa8A:undetectable;3asnJ-3wa8A:undetectable","3asnA-3wa8A:13.36;3asnJ-3wa8A:15.74"],["3ASN_W_CHDW1059_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.81A","3asnN-3wa8A:undetectable;3asnW-3wa8A:undetectable","3asnN-3wa8A:13.36;3asnW-3wa8A:15.74"],["3ASO_J_CHDJ60_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.70A","3asoA-3wa8A:undetectable;3asoJ-3wa8A:undetectable","3asoA-3wa8A:13.36;3asoJ-3wa8A:15.74"],["3WEO_A_ACRA1001_2","ALPHA-GLUCOSIDASE","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"ILE A 128;ILE A 157;MET A 145;TRP A 180","None","1.08A","3weoA-3wa8A:undetectable","3weoA-3wa8A:12.28"],["4KR3_A_GLYA701_0","GLYCINE--TRNA LIGASE","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"ARG A  13;ARG A 104;GLU A 161;SER A 160","None;None;None; HG A 302 ( 4.2A)","1.29A","4kr3A-3wa8A:undetectable","4kr3A-3wa8A:15.36"],["5B1B_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","1.01A","5b1bA-3wa8A:undetectable;5b1bJ-3wa8A:undetectable","5b1bA-3wa8A:13.36;5b1bJ-3wa8A:15.74"],["5IY5_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.82A","5iy5A-3wa8A:undetectable;5iy5J-3wa8A:undetectable","5iy5A-3wa8A:13.36;5iy5J-3wa8A:15.74"],["5N0S_B_SAMB501_0","PEPTIDE N-METHYLTRANSFERASE","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",5,"ILE A 155;SER A  74;GLN A 147;ILE A 110;ALA A 109","None","1.16A","5n0sB-3wa8A:undetectable","5n0sB-3wa8A:21.11"],["5OY0_2_PQN2843_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",5,"ILE A 194;PHE A 184;ILE A 149;ALA A 109;ALA A 183","None","1.13A","5oy02-3wa8A:undetectable","5oy02-3wa8A:14.29"],["5X1F_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.86A","5x1fA-3wa8A:undetectable;5x1fJ-3wa8A:undetectable","5x1fA-3wa8A:13.36;5x1fJ-3wa8A:15.74"],["5XDQ_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.93A","5xdqN-3wa8A:undetectable;5xdqW-3wa8A:undetectable","5xdqN-3wa8A:13.36;5xdqW-3wa8A:15.74"],["5XDX_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.84A","5xdxA-3wa8A:undetectable;5xdxJ-3wa8A:undetectable","5xdxA-3wa8A:13.36;5xdxJ-3wa8A:15.74"],["5XDX_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.93A","5xdxN-3wa8A:undetectable;5xdxW-3wa8A:undetectable","5xdxN-3wa8A:13.36;5xdxW-3wa8A:15.74"],["6B0C_D_TA1D502_1","TUBULIN BETA CHAIN","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",5,"LEU A 138;LEU A 166;LEU A 142;GLY A  30;LEU A  31","None; HG A 301 ( 3.9A);None;None;None","0.88A","6b0cD-3wa8A:undetectable","6b0cD-3wa8A:18.59"],["6NMF_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.82A","6nmfA-3wa8A:undetectable;6nmfJ-3wa8A:undetectable","6nmfA-3wa8A:13.36;6nmfJ-3wa8A:15.74"],["6NMP_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3wa8","CRISPR-ASSOCIATED PROTEIN, CSE2 FAMILY","Meiothermus ruber",4,"LEU A  68;ARG A 164;THR A 105;LEU A 106","None","0.87A","6nmpA-3wa8A:undetectable;6nmpJ-3wa8A:undetectable","6nmpA-3wa8A:13.36;6nmpJ-3wa8A:15.74"]]