SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wad'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		4 / 7 LEU A  77
LEU A  79
MET A 106
GLN A  98
 None
 1.11A 1kt3A-3wadA:
undetectable		 1kt3A-3wadA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		4 / 4 ALA A 142
VAL A 116
ALA A 139
HIS A 147
 None
 1.20A 1q23A-3wadA:
undetectable		 1q23A-3wadA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		4 / 4 ALA A 142
VAL A 116
ALA A 139
HIS A 147
 None
 1.11A 1q23F-3wadA:
undetectable		 1q23F-3wadA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		5 / 11 LEU A 376
LEU A 256
ILE A 276
THR A 265
VAL A 299
 None
 1.19A 2qd3A-3wadA:
2.9		 2qd3A-3wadA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		4 / 4 GLN A 336
PRO A 335
VAL A 334
GLU A 390
 None
 1.43A 3huoA-3wadA:
undetectable		 3huoA-3wadA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		5 / 11 ILE A 338
ILE A 330
PHE A 353
ALA A 359
GLY A 333
 None
 0.87A 3kw4A-3wadA:
undetectable		 3kw4A-3wadA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		5 / 11 GLY A 231
ARG A  11
ALA A  42
LEU A  14
ALA A 119
 None
 0.96A 4l6v1-3wadA:
undetectable
4l6v6-3wadA:
undetectable		 4l6v1-3wadA:
21.20
4l6v6-3wadA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		5 / 11 GLY A 231
ARG A  11
ALA A  42
LEU A  14
ALA A 139
 None
 1.23A 4l6v1-3wadA:
undetectable
4l6v6-3wadA:
undetectable		 4l6v1-3wadA:
21.20
4l6v6-3wadA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		5 / 12 THR A 283
THR A 325
GLY A 231
PRO A 232
ALA A 233
 None
 1.19A 4ypmA-3wadA:
undetectable		 4ypmA-3wadA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		4 / 6 ARG A 245
ASP A 277
ARG A 377
ILE A 380
 None
 1.34A 5a06A-3wadA:
6.0		 5a06A-3wadA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		3 / 3 TRP A 129
ARG A 149
LEU A 184
 None
 0.79A 5dbyA-3wadA:
undetectable		 5dbyA-3wadA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		3 / 3 ARG A 247
PHE A 304
LEU A 239
 None
 0.94A 5x1bC-3wadA:
undetectable		 5x1bC-3wadA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		4 / 7 VAL A 349
VAL A 361
PRO A 340
GLY A 321
 None
 0.90A 5x80C-3wadA:
undetectable
5x80D-3wadA:
undetectable		 5x80C-3wadA:
18.03
5x80D-3wadA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		5 / 12 GLY A 347
VAL A 364
ILE A 392
ALA A 359
ALA A 358
 None
 0.99A 6c2mD-3wadA:
undetectable		 6c2mD-3wadA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		4 / 5 VAL A 148
LEU A 206
HIS A 226
THR A 405
 None
 1.48A 6dyoA-3wadA:
undetectable		 6dyoA-3wadA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 3wad GLYCOSYLTRANSFERASE
(Streptomyces
halstedii) 		3 / 3 ARG A 176
GLY A 169
GLU A 170
 None
 0.55A 6fgdA-3wadA:
undetectable		 6fgdA-3wadA:
23.19