SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3waj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 7 PHE A 168
SER A 155
ALA A 167
PHE A 151
 None
 1.02A 1fxvA-3wajA:
1.7
1fxvB-3wajA:
undetectable		 1fxvA-3wajA:
13.32
1fxvB-3wajA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 11 PHE A 405
ALA A 232
SER A 287
ILE A 290
ALA A 291
 None
 0.89A 1ha2A-3wajA:
2.9		 1ha2A-3wajA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		3 / 3 PHE A  68
TYR A 540
PRO A  70
 None
 1.04A 1mcnA-3wajA:
2.6
1mcnB-3wajA:
undetectable
1mcnP-3wajA:
undetectable		 1mcnA-3wajA:
14.30
1mcnB-3wajA:
14.30
1mcnP-3wajA:
0.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		3 / 3 ASP A 161
HIS A 162
HIS A 163
 ZN  A 901 (-2.7A)
SO4  A 902 (-3.8A)
ZN  A 901 (-3.3A)
 0.63A 1oe1A-3wajA:
undetectable		 1oe1A-3wajA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		3 / 3 ASP A 161
HIS A 162
HIS A 163
 ZN  A 901 (-2.7A)
SO4  A 902 (-3.8A)
ZN  A 901 (-3.3A)
 0.63A 1oe3A-3wajA:
undetectable		 1oe3A-3wajA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 7 LEU A 246
PHE A 228
ALA A 250
ILE A 221
 None
 0.67A 1oniB-3wajA:
undetectable
1oniC-3wajA:
undetectable		 1oniB-3wajA:
11.58
1oniC-3wajA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 6 TYR A 708
GLU A 727
PRO A 738
VAL A 745
 None
 1.37A 1q13A-3wajA:
undetectable		 1q13A-3wajA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 116
ILE A 164
PRO A 123
VAL A 124
ILE A 121
 None
 1.12A 1sduB-3wajA:
undetectable		 1sduB-3wajA:
7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  43
LEU A 157
ALA A 114
ILE A 115
ILE A  55
 None
 1.01A 1tw4A-3wajA:
undetectable		 1tw4A-3wajA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 6 TYR A 595
ALA A 626
SER A 586
ASN A 580
 None
 1.17A 1yvpB-3wajA:
2.2		 1yvpB-3wajA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 THR A  72
PRO A  70
TYR A 524
TYR A  50
LEU A  54
 None
 1.36A 1z9hA-3wajA:
2.2		 1z9hA-3wajA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 THR A  72
PRO A  70
TYR A 524
TYR A  50
LEU A  54
 None
 1.36A 1z9hB-3wajA:
undetectable		 1z9hB-3wajA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 THR A  72
PRO A  70
TYR A 524
TYR A  50
LEU A  54
 None
 1.36A 1z9hC-3wajA:
2.3		 1z9hC-3wajA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		3 / 3 THR A  72
PRO A  75
PRO A 565
 None
 0.79A 2d55C-3wajA:
undetectable		 2d55C-3wajA:
1.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		3 / 3 THR A  58
PRO A  63
TYR A  88
 None
 0.94A 2dxrA-3wajA:
undetectable		 2dxrA-3wajA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 11 ALA A 120
ILE A 164
ILE A 144
ALA A 433
ALA A 167
 None
 1.15A 2qhfA-3wajA:
undetectable		 2qhfA-3wajA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		3 / 3 ASP A 161
HIS A 162
HIS A 163
 ZN  A 901 (-2.7A)
SO4  A 902 (-3.8A)
ZN  A 901 (-3.3A)
 0.64A 2xxgA-3wajA:
undetectable		 2xxgA-3wajA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		3 / 3 ASP A 161
HIS A 162
HIS A 163
 ZN  A 901 (-2.7A)
SO4  A 902 (-3.8A)
ZN  A 901 (-3.3A)
 0.68A 2xxgC-3wajA:
undetectable		 2xxgC-3wajA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 7 VAL A 624
ILE A 574
GLY A 573
LEU A 603
 None
 0.66A 3bjwB-3wajA:
2.0		 3bjwB-3wajA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 7 VAL A 624
ILE A 574
GLY A 573
LEU A 603
 None
 0.69A 3bjwF-3wajA:
undetectable		 3bjwF-3wajA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 7 VAL A 624
ILE A 574
GLY A 573
LEU A 603
 None
 0.69A 3bjwH-3wajA:
2.4		 3bjwH-3wajA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 116
ILE A 164
PRO A 123
VAL A 124
ILE A 121
 None
 1.30A 3ekyB-3wajA:
undetectable		 3ekyB-3wajA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 11 ILE A 144
ALA A 140
TRP A 413
ALA A 137
ILE A 164
 None
 1.01A 3fc6A-3wajA:
undetectable		 3fc6A-3wajA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 239
ALA A 241
LEU A 174
LEU A 178
ILE A 221
 None
 1.02A 3gcsA-3wajA:
undetectable		 3gcsA-3wajA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 7 GLU A 166
TYR A 276
PHE A 427
TYR A 430
 SO4  A 902 ( 4.8A)
None
None
None
 1.28A 3ku9B-3wajA:
undetectable		 3ku9B-3wajA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		3 / 3 ASP A 302
GLU A 307
SER A 247
 None
 0.85A 3p2kA-3wajA:
undetectable		 3p2kA-3wajA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 6 VAL A 608
VAL A 771
ILE A 557
ARG A 694
 None
 1.10A 3pyyA-3wajA:
undetectable		 3pyyA-3wajA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 4 LEU A 127
GLY A 175
LEU A 178
GLU A 130
 None
 1.12A 3tgvB-3wajA:
undetectable		 3tgvB-3wajA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 8 TYR A 832
TRP A 509
TYR A 607
LEU A 507
 None
 1.15A 3wipG-3wajA:
undetectable
3wipH-3wajA:
undetectable		 3wipG-3wajA:
13.05
3wipH-3wajA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 8 LEU A 507
TYR A 832
TRP A 509
TYR A 607
 None
 1.16A 3wipF-3wajA:
undetectable
3wipJ-3wajA:
undetectable		 3wipF-3wajA:
13.05
3wipJ-3wajA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 ALA A 114
GLY A 116
GLY A 117
ILE A 156
GLY A 158
 None
 0.90A 4obwB-3wajA:
undetectable		 4obwB-3wajA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		3 / 3 TYR A 276
GLY A  83
PRO A  84
 None
 0.65A 4qwpA-3wajA:
undetectable		 4qwpA-3wajA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 760
TYR A 749
ILE A 665
GLY A 639
LEU A 754
 None
 1.22A 4zdyA-3wajA:
undetectable		 4zdyA-3wajA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 8 ASN A 160
PHE A 159
SER A 155
TRP A 165
 None
 1.34A 5amiB-3wajA:
undetectable		 5amiB-3wajA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 11 VAL A 793
VAL A 795
ILE A 864
ILE A 851
LEU A 868
 None
 0.95A 5e4dB-3wajA:
undetectable		 5e4dB-3wajA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 5 THR A 838
ALA A 797
THR A 798
HIS A 841
 None
 1.14A 5ecmA-3wajA:
undetectable		 5ecmA-3wajA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		3 / 3 VAL A 771
SER A 549
MET A 678
 None
 0.83A 5ikqA-3wajA:
0.1		 5ikqA-3wajA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 9 GLY A 116
ILE A 164
PRO A 123
VAL A 124
ILE A 121
 None
 1.16A 5kr0A-3wajA:
undetectable		 5kr0A-3wajA:
7.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 11 GLY A 116
ILE A 164
PRO A 123
VAL A 124
ILE A 121
 None
 1.27A 5kr2B-3wajA:
undetectable		 5kr2B-3wajA:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 8 VAL A 795
GLY A 784
LEU A 868
THR A 819
 None
 1.01A 5sxqA-3wajA:
undetectable		 5sxqA-3wajA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 8 VAL A 795
GLY A 784
LEU A 868
THR A 819
 None
 1.00A 5sxtA-3wajA:
undetectable		 5sxtA-3wajA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 8 ALA A 288
ILE A 225
ALA A 222
LEU A 226
 None
 0.78A 5te8B-3wajA:
0.7		 5te8B-3wajA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_C_HFGC1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 PHE A 807
ARG A 805
GLU A 615
PHE A 774
SER A 610
 None
 1.50A 5xiqC-3wajA:
undetectable		 5xiqC-3wajA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 158
PRO A 499
GLY A 498
ASN A 160
PHE A 111
 None
 1.34A 5yn6A-3wajA:
undetectable		 5yn6A-3wajA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_H_BEZH201_0
(NS3 PROTEASE)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 5 HIS A 683
SER A 768
TYR A 701
GLY A 769
 None
 1.18A 5yodH-3wajA:
2.3		 5yodH-3wajA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 171
LEU A 174
VAL A 437
ALA A 409
LEU A 410
 None
 1.06A 6ajiA-3wajA:
undetectable		 6ajiA-3wajA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 7 VAL A  36
PRO A 148
LEU A 488
LEU A 152
 None
 1.12A 6aycA-3wajA:
undetectable		 6aycA-3wajA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3waj TRANSMEMBRANE
OLIGOSACCHARYL
TRANSFERASE
(Archaeoglobus
fulgidus) 		4 / 5 LEU A 754
TYR A 755
ILE A 612
GLY A 638
 None
 1.08A 6hd6A-3wajA:
undetectable		 6hd6A-3wajA:
6.42