SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wau'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_GLYA1292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	4 / 8	SER A 302 LYS A 251 TYR A 246 PHE A 369	None	1.20A	1eqbA-3wauA: undetectable 1eqbB-3wauA: undetectable	1eqbA-3wauA: 22.27 1eqbB-3wauA: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_B_GLYB2292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	4 / 8	TYR A 246 PHE A 369 SER A 302 LYS A 251	None	1.23A	1eqbA-3wauA: undetectable 1eqbB-3wauA: undetectable	1eqbA-3wauA: 22.27 1eqbB-3wauA: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_C_GLYC3292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	4 / 8	SER A 302 LYS A 251 TYR A 246 PHE A 369	None	1.21A	1eqbC-3wauA: undetectable 1eqbD-3wauA: undetectable	1eqbC-3wauA: 22.27 1eqbD-3wauA: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_D_GLYD4292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	4 / 8	TYR A 246 PHE A 369 SER A 302 LYS A 251	None	1.23A	1eqbC-3wauA: undetectable 1eqbD-3wauA: undetectable	1eqbC-3wauA: 22.27 1eqbD-3wauA: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1G50_B_ESTB1600_1 (ESTROGEN RECEPTOR)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	5 / 12	GLU A 314 LEU A 323 ARG A 35 ILE A 250 GLY A 274	None	1.23A	1g50B-3wauA: undetectable	1g50B-3wauA: 21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1G50_C_ESTC2600_1 (ESTROGEN RECEPTOR)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	5 / 11	GLU A 314 LEU A 323 ARG A 35 ILE A 250 GLY A 274	None	1.23A	1g50C-3wauA: undetectable	1g50C-3wauA: 21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TLS_B_C2FB266_0 (THYMIDYLATE SYNTHASE)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	5 / 12	ILE A 142 LEU A 86 GLY A 75 VAL A 100 ALA A 101	None	1.05A	1tlsB-3wauA: undetectable	1tlsB-3wauA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XZ5_A_ACHA1211_0 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	4 / 7	SER A 219 GLN A 190 ILE A 241 SER A 188	None	1.22A	2xz5A-3wauA: undetectable 2xz5B-3wauA: undetectable	2xz5A-3wauA: 19.13 2xz5B-3wauA: 19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UPR_A_1KXA277_1 (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	5 / 10	ILE A 107 VAL A 349 TYR A 340 TYR A 83 ILE A 329	None	1.26A	3uprA-3wauA: undetectable	3uprA-3wauA: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VRJ_A_1KXA301_1 (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN 10-MER PEPTIDE)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	5 / 12	ILE A 107 VAL A 349 TYR A 340 TYR A 83 ILE A 329	None	1.28A	3vrjA-3wauA: undetectable 3vrjC-3wauA: undetectable	3vrjA-3wauA: 22.08 3vrjC-3wauA: 3.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DRJ_A_RAPA201_2 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4 SERINE/THREONINE-PRO TEIN KINASE MTOR)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	4 / 8	LEU A 12 PHE A 4 ASP A 53 TYR A 52	None	1.07A	4drjB-3wauA: undetectable	4drjB-3wauA: 13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FQS_A_LYAA302_1 (THYMIDYLATE SYNTHASE)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	5 / 12	ILE A 77 LEU A 86 GLY A 75 VAL A 100 ALA A 101	None	1.22A	4fqsA-3wauA: undetectable	4fqsA-3wauA: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FQS_B_LYAB302_1 (THYMIDYLATE SYNTHASE)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	5 / 12	ILE A 77 LEU A 86 GLY A 75 VAL A 100 ALA A 101	None	1.20A	4fqsB-3wauA: undetectable	4fqsB-3wauA: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZT_A_ACTA202_0 (RETINOL-BINDING PROTEIN 2)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	4 / 6	TYR A 204 THR A 135 LEU A 195 TRP A 141	None	1.30A	4qztA-3wauA: undetectable	4qztA-3wauA: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GTR_A_ESTA601_1 (ESTROGEN RECEPTOR)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	5 / 12	GLU A 314 LEU A 323 ARG A 35 ILE A 250 GLY A 274	None	1.10A	5gtrA-3wauA: undetectable	5gtrA-3wauA: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJB_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	5 / 12	LEU A 357 PRO A 259 PHE A 307 TYR A 339 LEU A 134	None	1.33A	5ljbA-3wauA: undetectable	5ljbA-3wauA: 15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U98_D_1KXD301_1 (HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	5 / 10	ILE A 107 VAL A 349 TYR A 340 TYR A 83 ILE A 329	None	1.27A	5u98D-3wauA: undetectable	5u98D-3wauA: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA305_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	3 / 3	THR A 42 MET A 347 HIS A 348	None	0.88A	5uunA-3wauA: undetectable	5uunA-3wauA: 22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C2M_C_SUEC1203_0 (NS3 PROTEASE)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	5 / 12	ASP A 131 GLY A 91 SER A 96 ALA A 99 VAL A 100	M1P A 404 (-2.9A) None None None None	0.87A	6c2mC-3wauA: undetectable	6c2mC-3wauA: 12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_C_GMJC301_1 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	4 / 6	TRP A 225 LEU A 269 GLN A 190 GLU A 257	None	1.25A	6djzC-3wauA: undetectable	6djzC-3wauA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMF_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3wau	4-O-BETA-D-MANNOSYL- D-GLUCOSE PHOSPHORYLASE (Bacteroides fragilis)	4 / 6	ILE A 354 LEU A 357 MET A 290 THR A 291	None	1.14A	6nmfN-3wauA: undetectable 6nmfW-3wauA: undetectable	6nmfN-3wauA: 22.67 6nmfW-3wauA: 9.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQB_A_GLYA1292_0","SERINE HYDROXYMETHYLTRANSFERASE","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",4,"SER A 302;LYS A 251;TYR A 246;PHE A 369","None","1.20A","1eqbA-3wauA:undetectable;1eqbB-3wauA:undetectable","1eqbA-3wauA:22.27;1eqbB-3wauA:22.27"],["1EQB_B_GLYB2292_0","SERINE HYDROXYMETHYLTRANSFERASE","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",4,"TYR A 246;PHE A 369;SER A 302;LYS A 251","None","1.23A","1eqbA-3wauA:undetectable;1eqbB-3wauA:undetectable","1eqbA-3wauA:22.27;1eqbB-3wauA:22.27"],["1EQB_C_GLYC3292_0","SERINE HYDROXYMETHYLTRANSFERASE","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",4,"SER A 302;LYS A 251;TYR A 246;PHE A 369","None","1.21A","1eqbC-3wauA:undetectable;1eqbD-3wauA:undetectable","1eqbC-3wauA:22.27;1eqbD-3wauA:22.27"],["1EQB_D_GLYD4292_0","SERINE HYDROXYMETHYLTRANSFERASE","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",4,"TYR A 246;PHE A 369;SER A 302;LYS A 251","None","1.23A","1eqbC-3wauA:undetectable;1eqbD-3wauA:undetectable","1eqbC-3wauA:22.27;1eqbD-3wauA:22.27"],["1G50_B_ESTB1600_1","ESTROGEN RECEPTOR","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",5,"GLU A 314;LEU A 323;ARG A  35;ILE A 250;GLY A 274","None","1.23A","1g50B-3wauA:undetectable","1g50B-3wauA:21.23"],["1G50_C_ESTC2600_1","ESTROGEN RECEPTOR","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",5,"GLU A 314;LEU A 323;ARG A  35;ILE A 250;GLY A 274","None","1.23A","1g50C-3wauA:undetectable","1g50C-3wauA:21.23"],["1TLS_B_C2FB266_0","THYMIDYLATE SYNTHASE","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",5,"ILE A 142;LEU A  86;GLY A  75;VAL A 100;ALA A 101","None","1.05A","1tlsB-3wauA:undetectable","1tlsB-3wauA:22.22"],["2XZ5_A_ACHA1211_0","SOLUBLE ACETYLCHOLINE RECEPTOR","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",4,"SER A 219;GLN A 190;ILE A 241;SER A 188","None","1.22A","2xz5A-3wauA:undetectable;2xz5B-3wauA:undetectable","2xz5A-3wauA:19.13;2xz5B-3wauA:19.13"],["3UPR_A_1KXA277_1","HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",5,"ILE A 107;VAL A 349;TYR A 340;TYR A  83;ILE A 329","None","1.26A","3uprA-3wauA:undetectable","3uprA-3wauA:22.28"],["3VRJ_A_1KXA301_1","HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN;10-MER PEPTIDE","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",5,"ILE A 107;VAL A 349;TYR A 340;TYR A  83;ILE A 329","None","1.28A","3vrjA-3wauA:undetectable;3vrjC-3wauA:undetectable","3vrjA-3wauA:22.08;3vrjC-3wauA:3.46"],["4DRJ_A_RAPA201_2","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP4;SERINE\/THREONINE-PROTEIN KINASE MTOR","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",4,"LEU A  12;PHE A   4;ASP A  53;TYR A  52","None","1.07A","4drjB-3wauA:undetectable","4drjB-3wauA:13.62"],["4FQS_A_LYAA302_1","THYMIDYLATE SYNTHASE","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",5,"ILE A  77;LEU A  86;GLY A  75;VAL A 100;ALA A 101","None","1.22A","4fqsA-3wauA:undetectable","4fqsA-3wauA:21.20"],["4FQS_B_LYAB302_1","THYMIDYLATE SYNTHASE","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",5,"ILE A  77;LEU A  86;GLY A  75;VAL A 100;ALA A 101","None","1.20A","4fqsB-3wauA:undetectable","4fqsB-3wauA:21.20"],["4QZT_A_ACTA202_0","RETINOL-BINDING PROTEIN 2","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",4,"TYR A 204;THR A 135;LEU A 195;TRP A 141","None","1.30A","4qztA-3wauA:undetectable","4qztA-3wauA:16.25"],["5GTR_A_ESTA601_1","ESTROGEN RECEPTOR","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",5,"GLU A 314;LEU A 323;ARG A  35;ILE A 250;GLY A 274","None","1.10A","5gtrA-3wauA:undetectable","5gtrA-3wauA:21.20"],["5LJB_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",5,"LEU A 357;PRO A 259;PHE A 307;TYR A 339;LEU A 134","None","1.33A","5ljbA-3wauA:undetectable","5ljbA-3wauA:15.63"],["5U98_D_1KXD301_1","HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",5,"ILE A 107;VAL A 349;TYR A 340;TYR A  83;ILE A 329","None","1.27A","5u98D-3wauA:undetectable","5u98D-3wauA:22.28"],["5UUN_A_ACTA305_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",3,"THR A  42;MET A 347;HIS A 348","None","0.88A","5uunA-3wauA:undetectable","5uunA-3wauA:22.42"],["6C2M_C_SUEC1203_0","NS3 PROTEASE","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",5,"ASP A 131;GLY A  91;SER A  96;ALA A  99;VAL A 100","M1P A 404 (-2.9A);None;None;None;None","0.87A","6c2mC-3wauA:undetectable","6c2mC-3wauA:12.36"],["6DJZ_C_GMJC301_1","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",4,"TRP A 225;LEU A 269;GLN A 190;GLU A 257","None","1.25A","6djzC-3wauA:undetectable","6djzC-3wauA:20.40"],["6NMF_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3wau","4-O-BETA-D-MANNOSYL-D-GLUCOSE PHOSPHORYLASE","Bacteroides fragilis",4,"ILE A 354;LEU A 357;MET A 290;THR A 291","None","1.14A","6nmfN-3wauA:undetectable;6nmfW-3wauA:undetectable","6nmfN-3wauA:22.67;6nmfW-3wauA:9.82"]]