SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wb1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 3wb1 UNCHARACTERIZED
PROTEIN MJ0488
(Methanocaldococc
us
jannaschii) 		4 / 6 GLU A   5
ILE A 116
TYR A  99
GLY A  87
 SO4  A 201 ( 4.7A)
None
None
None
 0.86A 1maaB-3wb1A:
undetectable
1maaD-3wb1A:
undetectable		 1maaB-3wb1A:
13.66
1maaD-3wb1A:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 3wb1 UNCHARACTERIZED
PROTEIN MJ0488
(Methanocaldococc
us
jannaschii) 		5 / 9 ASP A 118
LEU A  91
VAL A  42
ILE A  41
ILE A  35
 None
 1.31A 1q6iA-3wb1A:
undetectable		 1q6iA-3wb1A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 3wb1 UNCHARACTERIZED
PROTEIN MJ0488
(Methanocaldococc
us
jannaschii) 		5 / 10 ASP A 118
LEU A  91
VAL A  42
ILE A  41
ILE A  35
 None
 1.23A 1q6iB-3wb1A:
undetectable		 1q6iB-3wb1A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 3wb1 UNCHARACTERIZED
PROTEIN MJ0488
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A  69
ASN A  46
ALA A  76
VAL A 115
ILE A  71
 None
 1.10A 3czhB-3wb1A:
undetectable		 3czhB-3wb1A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 3wb1 UNCHARACTERIZED
PROTEIN MJ0488
(Methanocaldococc
us
jannaschii) 		5 / 11 ALA A  64
ILE A  66
ILE A  54
LEU A 147
ILE A 100
 None
 0.95A 4dt8A-3wb1A:
undetectable		 4dt8A-3wb1A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 3wb1 UNCHARACTERIZED
PROTEIN MJ0488
(Methanocaldococc
us
jannaschii) 		5 / 10 ALA A  64
ILE A  66
ILE A  54
LEU A 147
ILE A 100
 None
 0.93A 4dt8B-3wb1A:
undetectable		 4dt8B-3wb1A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 3wb1 UNCHARACTERIZED
PROTEIN MJ0488
(Methanocaldococc
us
jannaschii) 		4 / 5 ARG A 102
SER A 112
SER A 129
SER A 127
 SO4  A 203 (-4.6A)
SO4  A 203 (-3.4A)
None
None
 1.25A 5hswA-3wb1A:
undetectable		 5hswA-3wb1A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3wb1 UNCHARACTERIZED
PROTEIN MJ0488
(Methanocaldococc
us
jannaschii) 		4 / 6 THR A  45
ASN A  47
ILE A 139
GLU A 140
 SO4  A 202 (-3.4A)
None
None
None
 1.27A 5uigA-3wb1A:
undetectable		 5uigA-3wb1A:
17.00