SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wbd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G60_A_SAMA500_0
(ADENINE-SPECIFIC
METHYLTRANSFERASE
MBOIIA)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		5 / 12 PHE A  67
GLY A  69
SER A  70
THR A  77
ASN A  58
 None
 1.14A 1g60A-3wbdA:
undetectable		 1g60A-3wbdA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		5 / 7 GLY A 181
PRO A 180
THR A 185
ILE A 178
GLY A 183
 None
 1.11A 1usqA-3wbdA:
undetectable		 1usqA-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		4 / 6 GLY A 181
PRO A 180
ILE A 178
GLY A 183
 None
 0.82A 1usqB-3wbdA:
undetectable		 1usqB-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		4 / 6 GLY A 181
PRO A 180
ILE A 178
GLY A 183
 None
 0.82A 1usqC-3wbdA:
undetectable		 1usqC-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		4 / 6 GLY A 181
PRO A 180
ILE A 178
GLY A 183
 None
 0.83A 1usqD-3wbdA:
undetectable		 1usqD-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		4 / 6 GLY A 181
PRO A 180
ILE A 178
GLY A 183
 None
 0.82A 1usqE-3wbdA:
undetectable		 1usqE-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		5 / 7 GLY A 181
PRO A 180
THR A 185
ILE A 178
GLY A 183
 None
 1.10A 1usqF-3wbdA:
undetectable		 1usqF-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		5 / 7 GLY A 181
PRO A 180
THR A 185
ILE A 178
GLY A 183
 None
 1.13A 2jkjE-3wbdA:
undetectable		 2jkjE-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		5 / 7 GLY A 181
PRO A 180
THR A 185
ILE A 178
GLY A 183
 None
 1.13A 2jklA-3wbdA:
undetectable		 2jklA-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		5 / 7 GLY A 181
PRO A 180
THR A 185
ILE A 178
GLY A 183
 None
 1.14A 2jklC-3wbdA:
undetectable		 2jklC-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		5 / 7 GLY A 181
PRO A 180
THR A 185
ILE A 178
GLY A 183
 None
 1.13A 2jklD-3wbdA:
undetectable		 2jklD-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		5 / 7 GLY A 181
PRO A 180
THR A 185
ILE A 178
GLY A 183
 None
 1.13A 2jklE-3wbdA:
undetectable		 2jklE-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		5 / 7 GLY A 181
PRO A 180
THR A 185
ILE A 178
GLY A 183
 None
 1.13A 2jklF-3wbdA:
undetectable		 2jklF-3wbdA:
20.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PCP_B_1PCB227_1
(IMMUNOGLOBULIN)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		5 / 9 PHE A  94
GLY A  96
TYR A 101
HIS A 162
TYR A 160
 None
 1.11A 2pcpA-3wbdA:
22.6
2pcpB-3wbdA:
22.3		 2pcpA-3wbdA:
54.98
2pcpB-3wbdA:
35.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PCP_B_1PCB227_1
(IMMUNOGLOBULIN)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		6 / 9 TYR A  37
PHE A  94
GLY A  96
TYR A 101
TYR A 160
HIS A 162
 None
 0.64A 2pcpA-3wbdA:
22.6
2pcpB-3wbdA:
22.3		 2pcpA-3wbdA:
54.98
2pcpB-3wbdA:
35.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PCP_C_1PCC212_1
(IMMUNOGLOBULIN)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		6 / 10 HIS A  31
PHE A  94
GLY A  96
TYR A 101
HIS A 162
TYR A 160
 FLC  A2001 (-3.6A)
None
None
None
None
None
 1.11A 2pcpC-3wbdA:
22.6
2pcpD-3wbdA:
22.5		 2pcpC-3wbdA:
54.98
2pcpD-3wbdA:
35.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PCP_C_1PCC212_1
(IMMUNOGLOBULIN)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		7 / 10 HIS A  31
TYR A  37
PHE A  94
GLY A  96
TYR A 101
TYR A 160
HIS A 162
 FLC  A2001 (-3.6A)
None
None
None
None
None
None
 0.59A 2pcpC-3wbdA:
22.6
2pcpD-3wbdA:
22.5		 2pcpC-3wbdA:
54.98
2pcpD-3wbdA:
35.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		4 / 7 VAL A 139
ALA A 143
PRO A 136
THR A 238
 None
 0.94A 2q6oA-3wbdA:
undetectable		 2q6oA-3wbdA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		5 / 12 LEU A  78
GLN A  18
VAL A  83
LEU A 109
THR A 107
 None
 1.45A 2q7kA-3wbdA:
undetectable		 2q7kA-3wbdA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		4 / 5 ILE A 161
PRO A 180
TYR A 179
TYR A 160
 None
 1.04A 3d9lA-3wbdA:
undetectable
3d9lY-3wbdA:
undetectable		 3d9lA-3wbdA:
18.22
3d9lY-3wbdA:
4.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735
(Mus
musculus) 		4 / 4 PRO A 100
MET A 231
GLY A 226
VAL A 164
 None
 1.47A 6ak3A-3wbdA:
undetectable		 6ak3A-3wbdA:
15.85