SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wbx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 8 TRP A  81
TRP A  30
ALA A  55
LEU A  57
 None
 1.02A 2o01A-3wbxA:
undetectable		 2o01A-3wbxA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 11 VAL A  52
LEU A  27
GLY A  28
PRO A  34
THR A  37
 None
 1.03A 3bjwB-3wbxA:
undetectable		 3bjwB-3wbxA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 11 VAL A  52
LEU A  27
GLY A  28
PRO A  34
THR A  37
 None
 1.04A 3bjwE-3wbxA:
undetectable		 3bjwE-3wbxA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 VAL A  52
LEU A  27
GLY A  28
PRO A  34
THR A  37
 None
 1.03A 3bjwF-3wbxA:
undetectable		 3bjwF-3wbxA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 11 VAL A  52
LEU A  27
GLY A  28
PRO A  34
THR A  37
 None
 1.06A 3bjwH-3wbxA:
undetectable		 3bjwH-3wbxA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 PHE A  75
GLY A  26
SER A  51
ILE A 221
ASP A  53
 None
 1.19A 3iv6B-3wbxA:
undetectable		 3iv6B-3wbxA:
23.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R43_A_ID8A332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.55A 3r43A-3wbxA:
35.9		 3r43A-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R6I_A_JMSA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.55A 3r6iA-3wbxA:
36.1		 3r6iA-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R7M_A_SUZA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 10 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.51A 3r7mA-3wbxA:
36.0		 3r7mA-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R8G_A_IZPA409_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		6 / 9 LEU A  57
TYR A  58
HIS A 112
MET A 115
ASN A 144
PRO A 274
 None
 1.29A 3r8gA-3wbxA:
36.0		 3r8gA-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R94_A_FLRA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A  57
TYR A  58
HIS A 112
MET A 115
ASN A 144
 None
 1.09A 3r94A-3wbxA:
36.0		 3r94A-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R94_A_FLRA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A  57
TYR A  58
MET A 115
ASN A 144
PRO A 274
 None
 1.40A 3r94A-3wbxA:
36.0		 3r94A-3wbxA:
35.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 5 ILE A 205
PRO A 216
LYS A 207
GLY A 206
 None
 1.16A 3tkdB-3wbxA:
undetectable		 3tkdB-3wbxA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 5 ILE A 232
SER A 235
LYS A 234
GLY A  28
 None
None
SO4  A 301 (-4.2A)
None
 1.09A 3tkdB-3wbxA:
undetectable		 3tkdB-3wbxA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 5 ILE A 205
PRO A 216
LYS A 207
GLY A 206
 None
 1.17A 3tkdA-3wbxA:
undetectable		 3tkdA-3wbxA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 5 ILE A 232
SER A 235
LYS A 234
GLY A  28
 None
None
SO4  A 301 (-4.2A)
None
 1.08A 3tkdA-3wbxA:
undetectable		 3tkdA-3wbxA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 5 SER A 143
ILE A 153
GLY A 141
PRO A 161
 None
 1.05A 3uboB-3wbxA:
3.2		 3uboB-3wbxA:
23.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A  57
TYR A  58
MET A 115
ASN A 144
PRO A 274
 None
 1.41A 3ug8A-3wbxA:
36.0		 3ug8A-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A  57
TYR A  58
TRP A  81
ASN A 144
PRO A 274
 None
 0.86A 3ug8A-3wbxA:
36.0		 3ug8A-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.52A 3ug8A-3wbxA:
36.0		 3ug8A-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 7 TYR A  58
ASN A 144
GLU A 167
PRO A 274
 None
 0.99A 3ugrA-3wbxA:
35.8		 3ugrA-3wbxA:
35.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 6 PRO A 116
ASN A  82
ASN A 144
GLU A 146
 None
 0.98A 3zqtA-3wbxA:
undetectable		 3zqtA-3wbxA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 6 ALA A 217
GLY A 195
LEU A 200
VAL A 199
 None
SO4  A 301 (-3.6A)
None
None
 0.94A 4dubB-3wbxA:
undetectable		 4dubB-3wbxA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		3 / 3 GLU A 243
LYS A 239
ASN A 244
 None
 1.10A 4y1dA-3wbxA:
undetectable
4y1dD-3wbxA:
undetectable		 4y1dA-3wbxA:
23.18
4y1dD-3wbxA:
14.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.52A 4yvpB-3wbxA:
35.0		 4yvpB-3wbxA:
35.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVV_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 9 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.52A 4yvvA-3wbxA:
35.6		 4yvvA-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVV_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 9 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.52A 4yvvB-3wbxA:
35.6		 4yvvB-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVX_A_GMRA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.51A 4yvxA-3wbxA:
35.5		 4yvxA-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVX_B_GMRB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.51A 4yvxB-3wbxA:
35.5		 4yvxB-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZFC_A_GCZA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 9 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.52A 4zfcA-3wbxA:
35.5		 4zfcA-3wbxA:
35.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZFC_B_GCZB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 9 LEU A  57
TYR A  58
TRP A  81
HIS A 112
ASN A 144
 None
 0.51A 4zfcB-3wbxA:
35.7		 4zfcB-3wbxA:
35.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 5 THR A  54
ALA A  55
THR A  78
TYR A 109
 None
 1.05A 5ecmA-3wbxA:
undetectable		 5ecmA-3wbxA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 6 THR A  54
ALA A  55
THR A  78
TYR A 109
 None
 0.98A 5ecoA-3wbxA:
undetectable		 5ecoA-3wbxA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		4 / 9 PHE A 172
THR A 188
ASN A 164
ILE A 166
 None
 0.88A 5lg3I-3wbxA:
undetectable		 5lg3I-3wbxA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3wbx PUTATIVE
2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE
(Gluconobacter
oxydans) 		5 / 11 GLU A  39
GLY A  67
SER A  51
VAL A  29
ALA A  44
 None
 1.01A 5o96G-3wbxA:
undetectable		 5o96G-3wbxA:
22.18