SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wc3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 8 GLY A 168
GLY A  82
PHE A  83
GLY A 135
 None
 0.74A 1d0vA-3wc3A:
undetectable		 1d0vA-3wc3A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 4 THR A 288
LEU A 291
VAL A 294
LEU A 298
 GOL  A 506 (-4.7A)
GOL  A 506 ( 4.4A)
None
None
 0.77A 1fbmB-3wc3A:
undetectable		 1fbmB-3wc3A:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 4 THR A 288
LEU A 291
VAL A 294
LEU A 298
 GOL  A 506 (-4.7A)
GOL  A 506 ( 4.4A)
None
None
 0.90A 1fbmD-3wc3A:
undetectable		 1fbmD-3wc3A:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 ALA A 178
ALA A 177
PHE A  87
ALA A  86
ILE A 332
 None
 1.01A 1fm6U-3wc3A:
undetectable		 1fm6U-3wc3A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 ALA A 178
ALA A 177
PHE A  87
ILE A 332
LEU A 280
 None
 0.93A 1fm6U-3wc3A:
undetectable		 1fm6U-3wc3A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 8 GLY A 168
GLY A  82
PHE A  83
GLY A 135
 None
 0.78A 1jhaA-3wc3A:
undetectable		 1jhaA-3wc3A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 4 THR A 288
LEU A 291
VAL A 294
LEU A 298
 GOL  A 506 (-4.7A)
GOL  A 506 ( 4.4A)
None
None
 0.96A 1mz9D-3wc3A:
undetectable		 1mz9D-3wc3A:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 8 VAL A  79
ARG A 324
GLU A 431
ASP A  77
 None
GOL  A 509 (-3.1A)
GOL  A 505 ( 3.1A)
None
 1.01A 1s3zA-3wc3A:
undetectable
1s3zB-3wc3A:
undetectable		 1s3zA-3wc3A:
14.69
1s3zB-3wc3A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 7 TYR A  73
ASP A 143
ASP A  77
HIS A 378
 None
None
None
GOL  A 505 (-4.3A)
 1.49A 1t03A-3wc3A:
undetectable		 1t03A-3wc3A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 ALA A 178
ALA A 177
PHE A  87
ALA A  86
LEU A 280
 None
 1.06A 1xdkE-3wc3A:
undetectable		 1xdkE-3wc3A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 10 ALA A 178
ALA A 177
PHE A  87
ALA A  86
ILE A 332
 None
 1.04A 2aclC-3wc3A:
undetectable		 2aclC-3wc3A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 7 GLY A 259
ASP A 289
TYR A 256
THR A 282
 None
None
None
GOL  A 506 (-4.0A)
 1.03A 2aouB-3wc3A:
undetectable		 2aouB-3wc3A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 7 GLY A 321
PRO A 414
ASP A 415
THR A 310
 None
None
GOL  A 507 (-4.4A)
None
 1.17A 2aouB-3wc3A:
undetectable		 2aouB-3wc3A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 6 THR A  89
TYR A 183
TRP A 241
THR A 175
 None
 1.41A 2qmjA-3wc3A:
0.3		 2qmjA-3wc3A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 10 ILE A 116
LEU A  29
LEU A  92
GLY A 442
ALA A 445
 None
 1.16A 2xf3A-3wc3A:
undetectable		 2xf3A-3wc3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 10 VAL A 185
LEU A  29
LEU A  92
GLY A 442
ALA A 445
 None
 1.27A 2xf3A-3wc3A:
undetectable		 2xf3A-3wc3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 8 VAL A 185
LEU A  29
GLY A 442
ALA A 445
 None
 0.91A 2xfsA-3wc3A:
undetectable		 2xfsA-3wc3A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 8 VAL A 185
LEU A  29
GLY A 442
ALA A 445
 None
 0.91A 2xh9A-3wc3A:
undetectable		 2xh9A-3wc3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		3 / 3 GLU A  39
ASP A 435
TYR A 226
 None
GOL  A 509 ( 4.3A)
TRS  A 503 (-4.2A)
 0.79A 2yvlB-3wc3A:
undetectable		 2yvlB-3wc3A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 6 TYR A 256
ALA A 255
LEU A 252
ALA A 285
 None
 0.92A 3b6hA-3wc3A:
undetectable		 3b6hA-3wc3A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 5 ASN A  63
ALA A 166
LEU A 171
GLY A 135
 None
 0.96A 3dl9A-3wc3A:
undetectable		 3dl9A-3wc3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 ALA A 177
PHE A  87
ALA A  86
VAL A 335
ILE A 332
 None
 1.02A 3e00A-3wc3A:
undetectable		 3e00A-3wc3A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 ALA A 178
ALA A 177
PHE A  87
ALA A  86
ILE A 332
 None
 0.95A 3e00A-3wc3A:
undetectable		 3e00A-3wc3A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 10 ALA A 177
PHE A  87
ALA A  86
VAL A 335
ILE A 332
 None
 1.10A 3falA-3wc3A:
undetectable		 3falA-3wc3A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 11 ALA A 178
ALA A 177
PHE A  87
ALA A  86
ILE A 332
 None
 1.02A 3fc6A-3wc3A:
undetectable		 3fc6A-3wc3A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		3 / 3 GLU A 232
GLY A 259
THR A 260
 None
 0.56A 3iazA-3wc3A:
undetectable		 3iazA-3wc3A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 GLY A  82
VAL A  79
ALA A  75
ALA A 433
GLU A 431
 None
None
TRS  A 503 ( 4.7A)
None
GOL  A 505 ( 3.1A)
 0.98A 3mteB-3wc3A:
undetectable		 3mteB-3wc3A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 7 SER A 383
TRP A 147
PHE A 396
GLU A 395
 None
 1.41A 3n5tA-3wc3A:
undetectable
3n5tB-3wc3A:
undetectable		 3n5tA-3wc3A:
19.88
3n5tB-3wc3A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 LEU A  58
GLU A  39
GLY A  42
ASP A  43
LEU A  44
 None
None
None
NA  A 502 (-3.3A)
None
 1.23A 3ou6C-3wc3A:
undetectable		 3ou6C-3wc3A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		6 / 12 GLY A 238
ALA A 181
ALA A 180
LEU A 235
PHE A 258
LEU A 242
 None
 1.50A 3p2kA-3wc3A:
undetectable		 3p2kA-3wc3A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG8_B_TOYB305_1
(APH(2'')-ID)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 ASN A 434
SER A 381
HIS A 379
ASP A  77
GLU A 151
 None
 1.32A 3sg8B-3wc3A:
0.0		 3sg8B-3wc3A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 8 ASN A 434
SER A 381
HIS A 379
ASP A  77
GLU A 151
 None
 1.24A 3sg9B-3wc3A:
undetectable		 3sg9B-3wc3A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 7 ALA A 255
TYR A 243
ARG A 244
ALA A 285
 None
 1.04A 3twpB-3wc3A:
undetectable		 3twpB-3wc3A:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 7 ALA A 239
TYR A 243
ARG A 244
ALA A 285
 None
 1.11A 3twpC-3wc3A:
undetectable		 3twpC-3wc3A:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 7 ALA A 255
TYR A 243
ARG A 244
ALA A 285
 None
 0.86A 3twpC-3wc3A:
undetectable		 3twpC-3wc3A:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 ASP A  60
ALA A 159
ASN A  63
ASP A  77
ARG A 157
 None
 1.50A 3wemA-3wc3A:
undetectable		 3wemA-3wc3A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 ASP A  60
ALA A 159
ASN A  63
ASP A  77
ARG A 157
 None
 1.48A 3wenA-3wc3A:
undetectable		 3wenA-3wc3A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 ASP A  60
ALA A 159
ASN A  63
ASP A  77
ARG A 157
 None
 1.49A 3weoA-3wc3A:
undetectable		 3weoA-3wc3A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 9 GLY A  70
GLY A  71
ASN A 434
SER A  56
GLY A  42
 None
 1.27A 3ztvA-3wc3A:
undetectable		 3ztvA-3wc3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		3 / 3 TYR A 277
THR A 260
GLU A 234
 None
None
CA  A 501 (-2.2A)
 0.77A 4df3A-3wc3A:
undetectable		 4df3A-3wc3A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		3 / 3 TYR A 277
THR A 260
GLU A 234
 None
None
CA  A 501 (-2.2A)
 0.80A 4df3B-3wc3A:
undetectable		 4df3B-3wc3A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 7 TRP A 147
PHE A 396
GLU A 395
SER A 383
 None
 1.43A 4k5jA-3wc3A:
undetectable
4k5jB-3wc3A:
undetectable		 4k5jA-3wc3A:
20.08
4k5jB-3wc3A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 ALA A 222
GLY A 135
GLY A  82
PHE A  81
GLY A 138
 None
 1.14A 4n48B-3wc3A:
undetectable		 4n48B-3wc3A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		3 / 3 GLU A  37
ARG A  40
GLN A 108
 None
 0.86A 4rtbA-3wc3A:
undetectable		 4rtbA-3wc3A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 9 ALA A 177
ALA A 180
SER A 201
ALA A 245
ALA A 240
 None
 1.34A 4twdA-3wc3A:
1.9
4twdB-3wc3A:
2.0
4twdC-3wc3A:
undetectable
4twdD-3wc3A:
undetectable
4twdE-3wc3A:
undetectable		 4twdA-3wc3A:
18.34
4twdB-3wc3A:
18.34
4twdC-3wc3A:
18.34
4twdD-3wc3A:
18.34
4twdE-3wc3A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB203_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 9 TYR A 134
GLY A  62
GLY A  65
VAL A 128
ASP A  67
 None
 1.42A 5f8yB-3wc3A:
undetectable		 5f8yB-3wc3A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		5 / 12 GLY A  95
PHE A 440
ALA A 445
ILE A 450
ALA A 449
 None
 0.99A 5n0tB-3wc3A:
undetectable		 5n0tB-3wc3A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 5 ALA A 180
SER A 201
TYR A 205
TYR A 251
 None
 1.43A 5yodF-3wc3A:
undetectable		 5yodF-3wc3A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		6 / 12 ALA A 178
ALA A 177
PHE A  87
ALA A  86
ILE A 332
LEU A 280
 None
 1.02A 6a5zL-3wc3A:
undetectable		 6a5zL-3wc3A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		6 / 12 ALA A 178
ALA A 177
PHE A  87
ALA A  86
ILE A 332
LEU A 280
 None
 1.05A 6a60D-3wc3A:
undetectable		 6a60D-3wc3A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3wc3 ENDO-1,
4-BETA-GLUCANASE
(Eisenia
fetida) 		4 / 6 GLY A  95
TRP A  94
ALA A 181
LEU A 184
 None
 0.98A 6fosA-3wc3A:
undetectable		 6fosA-3wc3A:
11.69