SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wcq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3wcq FERREDOXIN
(Cyanidioschyzon
merolae) 		5 / 10 ARG A  41
GLY A  50
HIS A  91
THR A  77
ILE A  88
 None
 1.44A 1c9sG-3wcqA:
undetectable
1c9sH-3wcqA:
undetectable		 1c9sG-3wcqA:
25.25
1c9sH-3wcqA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3wcq FERREDOXIN
(Cyanidioschyzon
merolae) 		5 / 11 GLY A  50
HIS A  91
THR A  77
ILE A  88
ARG A  41
 None
 1.37A 1utdM-3wcqA:
undetectable
1utdN-3wcqA:
undetectable		 1utdM-3wcqA:
25.25
1utdN-3wcqA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 3wcq FERREDOXIN
(Cyanidioschyzon
merolae) 		4 / 6 THR A  83
CYH A  86
GLY A  55
ILE A  75
 None
 0.78A 3w9tF-3wcqA:
undetectable		 3w9tF-3wcqA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3wcq FERREDOXIN
(Cyanidioschyzon
merolae) 		4 / 7 TYR A  24
VAL A  57
ILE A  88
ILE A   4
 None
 0.84A 4lv9A-3wcqA:
undetectable		 4lv9A-3wcqA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3wcq FERREDOXIN
(Cyanidioschyzon
merolae) 		5 / 10 ARG A  41
GLY A  50
HIS A  91
THR A  77
ILE A  88
 None
 1.43A 5eeuH-3wcqA:
undetectable
5eeuI-3wcqA:
undetectable		 5eeuH-3wcqA:
25.25
5eeuI-3wcqA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3wcq FERREDOXIN
(Cyanidioschyzon
merolae) 		5 / 10 ARG A  41
GLY A  50
HIS A  91
THR A  77
ILE A  88
 None
 1.44A 5ef2D-3wcqA:
undetectable
5ef2E-3wcqA:
undetectable		 5ef2D-3wcqA:
25.25
5ef2E-3wcqA:
25.25