SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wd6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3VLN_A_ASCA904_0 (GLUTATHIONE S-TRANSFERASE OMEGA-1)	3wd6	OMEGA-CLASS GLUTATHIONE S-TRANSFERASE (Bombyx mori)	4 / 6	ARG A 43 PRO A 79 GLU A 91 SER A 92	None GSH A 306 (-4.3A) GSH A 306 (-3.0A) GSH A 306 (-2.6A)	0.28A	3vlnA-3wd6A: 29.0	3vlnA-3wd6A: 38.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PTJ_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	3wd6	OMEGA-CLASS GLUTATHIONE S-TRANSFERASE (Bombyx mori)	3 / 3	ASP A 141 LYS A 135 LEU A 132	None	0.93A	4ptjA-3wd6A: undetectable	4ptjA-3wd6A: 21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PTJ_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	3wd6	OMEGA-CLASS GLUTATHIONE S-TRANSFERASE (Bombyx mori)	3 / 3	ASP A 171 LYS A 120 LEU A 93	PEG A 305 (-3.8A) None None	1.04A	4ptjA-3wd6A: undetectable	4ptjA-3wd6A: 21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TIW_A_OAQA302_0 (SULFOTRANSFERASE)	3wd6	OMEGA-CLASS GLUTATHIONE S-TRANSFERASE (Bombyx mori)	5 / 12	ILE A 83 VAL A 94 LEU A 30 THR A 44 LEU A 48	None	1.26A	5tiwA-3wd6A: undetectable	5tiwA-3wd6A: 23.61

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3VLN_A_ASCA904_0","GLUTATHIONE S-TRANSFERASE OMEGA-1","3wd6","OMEGA-CLASS GLUTATHIONE S-TRANSFERASE","Bombyx mori",4,"ARG A  43;PRO A  79;GLU A  91;SER A  92","None;GSH A 306 (-4.3A);GSH A 306 (-3.0A);GSH A 306 (-2.6A)","0.28A","3vlnA-3wd6A:29.0","3vlnA-3wd6A:38.67"],["4PTJ_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","3wd6","OMEGA-CLASS GLUTATHIONE S-TRANSFERASE","Bombyx mori",3,"ASP A 141;LYS A 135;LEU A 132","None","0.93A","4ptjA-3wd6A:undetectable","4ptjA-3wd6A:21.51"],["4PTJ_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","3wd6","OMEGA-CLASS GLUTATHIONE S-TRANSFERASE","Bombyx mori",3,"ASP A 171;LYS A 120;LEU A  93","PEG A 305 (-3.8A);None;None","1.04A","4ptjA-3wd6A:undetectable","4ptjA-3wd6A:21.51"],["5TIW_A_OAQA302_0","SULFOTRANSFERASE","3wd6","OMEGA-CLASS GLUTATHIONE S-TRANSFERASE","Bombyx mori",5,"ILE A  83;VAL A  94;LEU A  30;THR A  44;LEU A  48","None","1.26A","5tiwA-3wd6A:undetectable","5tiwA-3wd6A:23.61"]]