SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wdq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 3wdq BETA-MANNANASE
(Symbiotic
protist
of
Reticulitermes
speratus) 		4 / 8 TYR A 308
LEU A  54
GLY A  57
ASP A  58
 None
 1.01A 1rmtC-3wdqA:
undetectable		 1rmtC-3wdqA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 3wdq BETA-MANNANASE
(Symbiotic
protist
of
Reticulitermes
speratus) 		5 / 12 LEU A 334
THR A 329
PHE A 304
MET A 286
ILE A  48
 None
 1.26A 2jjpA-3wdqA:
undetectable		 2jjpA-3wdqA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3wdq BETA-MANNANASE
(Symbiotic
protist
of
Reticulitermes
speratus) 		5 / 12 GLY A 203
ILE A 237
GLY A 194
ALA A 192
ALA A 233
 None
NA  A 403 (-4.6A)
None
None
None
 0.91A 3sudC-3wdqA:
undetectable		 3sudC-3wdqA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 3wdq BETA-MANNANASE
(Symbiotic
protist
of
Reticulitermes
speratus) 		3 / 3 GLU A 191
ALA A 192
PHE A 197
 None
 0.52A 4v1fA-3wdqA:
undetectable		 4v1fA-3wdqA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 3wdq BETA-MANNANASE
(Symbiotic
protist
of
Reticulitermes
speratus) 		3 / 3 GLU A 191
ALA A 192
PHE A 197
 None
 0.50A 4v1fC-3wdqA:
undetectable		 4v1fC-3wdqA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3wdq BETA-MANNANASE
(Symbiotic
protist
of
Reticulitermes
speratus) 		3 / 3 ARG A 281
ILE A 253
PHE A 278
 None
 0.73A 5kirA-3wdqA:
undetectable		 5kirA-3wdqA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3wdq BETA-MANNANASE
(Symbiotic
protist
of
Reticulitermes
speratus) 		6 / 12 LEU A  79
PRO A  77
ILE A 118
GLY A 117
ASP A 339
ILE A  48
 None
 1.39A 6emuA-3wdqA:
undetectable		 6emuA-3wdqA:
20.22