SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wdy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		3 / 3 THR A 248
PRO A  98
THR A  96
 None
 0.88A 1a7yB-3wdyA:
undetectable		 1a7yB-3wdyA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		3 / 3 THR A  96
THR A 248
PRO A  98
 None
 0.81A 1fjaC-3wdyA:
undetectable		 1fjaC-3wdyA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		3 / 3 THR A  96
THR A 248
PRO A  98
 None
 0.81A 1fjaD-3wdyA:
undetectable		 1fjaD-3wdyA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		3 / 3 THR A 248
PRO A  98
THR A  96
 None
 0.88A 1i3wE-3wdyA:
undetectable		 1i3wE-3wdyA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		4 / 8 GLY A 195
GLU A 235
TRP A 199
HIS A  79
 None
 1.09A 1maaD-3wdyA:
undetectable		 1maaD-3wdyA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA8_0
(GRAMICIDIN A)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		4 / 4 GLY A  95
VAL A  93
TRP A  97
GLY A 119
 None
None
CBI  A 301 (-4.7A)
None
 1.35A 1ng8A-3wdyA:
undetectable		 1ng8A-3wdyA:
4.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB8_0
(GRAMICIDIN A)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		4 / 4 GLY A  95
VAL A  93
TRP A  97
GLY A 119
 None
None
CBI  A 301 (-4.7A)
None
 1.35A 1ng8B-3wdyA:
undetectable		 1ng8B-3wdyA:
4.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		3 / 3 THR A 248
PRO A  98
THR A  96
 None
 0.85A 1unmF-3wdyA:
undetectable		 1unmF-3wdyA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		3 / 3 THR A  96
THR A 248
PRO A  98
 None
 0.82A 1unmF-3wdyA:
undetectable		 1unmF-3wdyA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		3 / 3 THR A  96
THR A 248
PRO A  98
 None
 0.74A 209dC-3wdyA:
undetectable		 209dC-3wdyA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		3 / 3 ASP A 276
ASN A 277
THR A  96
 None
 0.68A 2pymB-3wdyA:
undetectable		 2pymB-3wdyA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		3 / 3 ASP A 276
ASN A 277
THR A  96
 None
 0.71A 2q63B-3wdyA:
undetectable		 2q63B-3wdyA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_B_ACTB501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		4 / 6 ARG A 292
VAL A  83
ILE A 186
TYR A 294
 None
 1.13A 2yfbB-3wdyA:
undetectable		 2yfbB-3wdyA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		5 / 12 LEU A 243
VAL A  69
LEU A  71
ILE A 116
LEU A 291
 None
 0.98A 3cjtC-3wdyA:
undetectable		 3cjtC-3wdyA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		5 / 12 LEU A 243
VAL A  69
LEU A  71
ILE A 116
LEU A 291
 None
 0.97A 3cjtO-3wdyA:
undetectable		 3cjtO-3wdyA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		5 / 12 TRP A 286
ARG A 203
LEU A 291
THR A 102
ILE A 114
 None
 1.42A 3mneA-3wdyA:
undetectable		 3mneA-3wdyA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		4 / 7 ILE A 186
VAL A  83
ARG A 292
TYR A 294
 None
 1.07A 3p6hA-3wdyA:
undetectable		 3p6hA-3wdyA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		3 / 3 TYR A  52
MET A  53
ILE A 244
 None
 0.88A 4c8bB-3wdyA:
undetectable		 4c8bB-3wdyA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L64_A_C2FA802_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		4 / 7 SER A  68
TYR A  32
VAL A  55
TRP A 286
 None
 1.48A 4l64A-3wdyA:
undetectable		 4l64A-3wdyA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		5 / 12 GLY A 119
HIS A 127
ASP A 115
THR A 248
SER A  68
 None
None
CBI  A 301 (-3.7A)
None
None
 1.21A 4pooA-3wdyA:
undetectable		 4pooA-3wdyA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		5 / 12 GLY A  28
ASP A  24
PRO A  25
GLU A  72
TRP A  97
 None
None
None
None
CBI  A 301 (-4.7A)
 1.05A 5bw4A-3wdyA:
undetectable		 5bw4A-3wdyA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		3 / 3 ARG A  70
THR A  26
ASP A  24
 None
 0.94A 5g5gA-3wdyA:
undetectable
5g5gB-3wdyA:
undetectable		 5g5gA-3wdyA:
18.50
5g5gB-3wdyA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		4 / 8 TRP A 220
PHE A 200
GLU A 206
THR A 102
 None
 1.38A 5hqaA-3wdyA:
undetectable		 5hqaA-3wdyA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		4 / 8 ASP A 221
PHE A 201
SER A 197
SER A 205
 None
 1.13A 5l1fA-3wdyA:
undetectable
5l1fB-3wdyA:
undetectable		 5l1fA-3wdyA:
17.16
5l1fB-3wdyA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3wdy BETA-1,3-1,4-GLUCANA
SE
(Paecilomyces
sp.
'thermophila') 		4 / 8 ASP A 252
HIS A 127
GLU A 118
ASP A 115
 CBI  A 301 (-4.5A)
None
CBI  A 301 (-3.0A)
CBI  A 301 (-3.7A)
 1.00A 6mn4A-3wdyA:
undetectable		 6mn4A-3wdyA:
22.26