SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3we5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZY_D_BRLD478_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3we5	UBIQUITIN CONJUGATING ENZYME (Agrocybe aegerita)	5 / 12	LEU A 97 VAL A 110 LEU A 55 HIS A 91 TYR A 133	None	1.45A	3dzyD-3we5A: undetectable	3dzyD-3we5A: 18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PD4_C_AOQC4003_1 (CYTOCHROME B)	3we5	UBIQUITIN CONJUGATING ENZYME (Agrocybe aegerita)	5 / 12	GLY A 90 VAL A 86 ILE A 92 LEU A 55 TYR A 53	None	1.00A	4pd4C-3we5A: undetectable	4pd4C-3we5A: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PD4_C_AOQC4003_1 (CYTOCHROME B)	3we5	UBIQUITIN CONJUGATING ENZYME (Agrocybe aegerita)	5 / 12	GLY A 90 VAL A 86 ILE A 92 TYR A 53 LEU A 118	None	1.00A	4pd4C-3we5A: undetectable	4pd4C-3we5A: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YHA_F_MZMF302_1 (ALPHA-CARBONIC ANHYDRASE)	3we5	UBIQUITIN CONJUGATING ENZYME (Agrocybe aegerita)	5 / 10	ASP A 131 ASN A 130 HIS A 91 VAL A 134 ALA A 80	None	1.46A	4yhaF-3we5A: undetectable	4yhaF-3we5A: 20.42

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3DZY_D_BRLD478_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","3we5","UBIQUITIN CONJUGATING ENZYME","Agrocybe aegerita",5,"LEU A  97;VAL A 110;LEU A  55;HIS A  91;TYR A 133","None","1.45A","3dzyD-3we5A:undetectable","3dzyD-3we5A:18.08"],["4PD4_C_AOQC4003_1","CYTOCHROME B","3we5","UBIQUITIN CONJUGATING ENZYME","Agrocybe aegerita",5,"GLY A  90;VAL A  86;ILE A  92;LEU A  55;TYR A  53","None","1.00A","4pd4C-3we5A:undetectable","4pd4C-3we5A:17.65"],["4PD4_C_AOQC4003_1","CYTOCHROME B","3we5","UBIQUITIN CONJUGATING ENZYME","Agrocybe aegerita",5,"GLY A  90;VAL A  86;ILE A  92;TYR A  53;LEU A 118","None","1.00A","4pd4C-3we5A:undetectable","4pd4C-3we5A:17.65"],["4YHA_F_MZMF302_1","ALPHA-CARBONIC ANHYDRASE","3we5","UBIQUITIN CONJUGATING ENZYME","Agrocybe aegerita",5,"ASP A 131;ASN A 130;HIS A  91;VAL A 134;ALA A  80","None","1.46A","4yhaF-3we5A:undetectable","4yhaF-3we5A:20.42"]]